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Method for determining moisture of soft capsule rubber

A soft capsule and rubber technology, applied in the field of pharmaceutical processing and testing, and food, can solve problems such as affecting work efficiency, trouble for operators, and short time, and achieve the effects of reasonable and ingenious design, improved work efficiency, and convenient operation.

Inactive Publication Date: 2015-02-18
JIANGSU ZODIAC MARINE BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the prior art, some enterprises directly use moisture meter and other devices to measure the moisture content of the rubber. However, although the moisture meter is accurate in measurement and the time is short, the required temperature is high, and the purchase of equipment is expensive. high cost
[0004] In addition, the general operation of the existing laboratory is to take a certain amount of soft capsules and cut the capsule rubber, but when the capsule rubber is cut, the contents (usually oily liquid) in the capsule will easily flow to and stick to the surface. to the operator's lab coat or arm, thereby causing unnecessary trouble to the operator and affecting work efficiency

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0016] The technical solutions of the present invention will be described in further detail below in conjunction with specific embodiments.

[0017] The present embodiment provides a kind of method for measuring soft capsule rubber skin moisture, and it comprises the steps:

[0018] (1) suck out the content in the soft capsule with a suction piece to obtain an empty soft capsule rubber; wherein, the suction piece can be a syringe, or other devices that can suck out the content, so that the inside of the capsule can be The material is easy to flow and stick to the operator's lab coat or arm, which improves work efficiency.

[0019] (2) Cut the above-mentioned soft capsule rubber with a knife, and wipe off the residual content on the inner and outer surfaces with a solvent; specifically, the solvent used generally adopts ethanol or petroleum ether, because the contents are generally oily liquids, and ethanol or petroleum Ether has a good dissolution effect on these contents and...

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PUM

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Abstract

The invention discloses a method for determining the moisture of soft capsule rubber. The method comprises the following steps: (1) extracting content in a rubber capsule by virtue of a suction element to obtain hollow soft capsule rubber; (2) splitting the soft capsule rubber by virtue of a knife, and wiping the residual content on the inner and outer surfaces by virtue of a solvent; and (3) precisely weighing a certain weight of rubber, putting into a flat weighing bottle with constant weight, drying until reaching constant weight, and calculating weight loss on drying of the rubber, namely the moisture of the soft capsule rubber, according to the reduced weight and the weight of the rubber before being dried. According to the method disclosed by the invention, the practice that the capsule rubber is directly cut off in the traditional method and the content in the capsule easily flows to and sticks to a laboratory coat or arms of an operator is abandoned; and the content is firstly extracted and then is subjected to rubber moisture determination, so that the method is reasonable and ingenious in design, simple, effective, and convenient to operate; and the work efficiency can be effectively improved, and thus the moisture content of the rubber is quickly determined.

Description

technical field [0001] The invention relates to a method for measuring the water content of soft capsule rubber, which belongs to the field of food and medicine processing and testing. Background technique [0002] The capsule is the outer layer of the soft capsule. The raw material composition, water content, and preparation process of the rubber have a great influence on the properties of the rubber, such as plasticity, elasticity, wall thickness, disintegration time limit, and viscosity (too sticky will cause the capsules to stick to each other). influences. The main characteristics of rubber are strong plasticity and high elasticity, and its elasticity is related to the weight ratio of gelatin, plasticizer and water. Depending on the type of gelatin used, the amount of water also affects the properties of the rubber to varying degrees. Therefore, it is extremely important and significant to accurately measure the moisture content in the soft capsule rubber. [0003] I...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N5/04
Inventor 聂毅
Owner JIANGSU ZODIAC MARINE BIOTECH
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