A traditional Chinese medicine preparation for treating chronic kidney disease with deficiency of both qi and yin and its preparation method

Abstract

The invention discloses a traditional Chinese medicine preparation for treating qi-yin deficiency syndrome of a chronic kidney disease. The traditional Chinese medicine preparation comprises the following raw materials in parts by weight: 8-12 parts of dried radix rehmanniae, 8-12 parts of poria cocos, 8-12 parts of Chinese yam, 6-10 parts of dogwood, 8-12 parts of astragalus membranaceus, 8-12 parts of codonopsis pilosula, 8-12 parts of semen coicis, 8-12 parts of corn stigma, 12-18 parts of lalang grass rhizome, 8-12 parts of madder, 8-12 parts of herba cepbalanoplosis segeti, 8-12 parts of fructus rosae laevigatae and 8-12 parts of semen euryales. The preparation method comprises the following steps: during preparation, firstly, decocting various raw materials for three times according to the required ratio; mixing decoctions of three times; filtering and concentrating into thick paste of which the relative density is 1.2-1.3; and adding auxiliary materials, pelletizing and drying to prepare the traditional Chinese medicine preparation. The traditional Chinese medicine preparation has the efficacies of tonifying the kidneys and spleen, securing essence and clearing dampness, and tonifying qi and nourishing yin, and has a significant curative effect on hematuresis, proteinuria and abnormal renal function caused by chronic kidney diseases when the kidney function is protected.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and specifically relates to a traditional Chinese medicine preparation for treating chronic kidney disease with deficiency of both qi and yin and a preparation method thereof, and is particularly suitable for treating chronic kidney disease with deficiency of both qi and yin on the basis of protecting kidney function. Hematuria, proteinuria and abnormal renal function. Background technique [0002] In 2012, Kidney Disease: Improving Global Outcomes (KDIGO) clinical practice guidelines for the evaluation and management of chronic kidney disease (KDIGO) defined chronic kidney disease (CKD) as kidney damage or glomerular filtration rate in 2012. (GFR)<GFR<60ml / (min·1.73m 2 ) persists for more than 3 months. Clinically, it includes chronic glomerulonephritis, nephrotic syndrome, IgA nephropathy, chronic interstitial nephritis, various secondary kidney diseases, and chronic renal fa...

AI Technical Summary

Problems solved by technology

In 2012, led by Professor Wang Haiyan from the Nephrology Department of Peking University First Hospital, the results of a cross-sectional study involving 13 provinces, municipalities, and autonomous regions across the country "China Chronic Kidney Disease Epidemiological Survey" showed that the prevalence of CKD among people over the age of 18 in my country The rate is 10.8%. Based on this estimate, the existing CKD patients in my country will reach 120 million, but the awareness rate is only 12.5%.

[0005] Chinese patent: The patent authorization announcement number is CN1057465C, and the invention patent on October 18, 2000 discloses a medicine for treating chronic kidney disease and a preparation method thereof, which consists of the following medicines in parts by weight: Radix Astragali 8-16 , Angelica 1‐9, Ginseng 4‐12, Rehmannia 8‐16, Atractylodes 4‐12, Poria 4‐12, Alisma 4‐12, Danpi 4‐12, Coptidis 4‐12, Cinnamon 4‐12, Fangji 4‐12, Ophiopogon japonicus 4‐12, Schisandra 4‐12, this formula has the functions of invigorating qi and nourishing yin, drying damp and clearing heat, mainly for chronic renal failure and chronic renal insufficiency caused by deficiency of both qi and yin and accumulation of damp heat. Treatment of proteinuria such as glomerulonephritis and nephrotic syndrome, but no clear curative effect on hematuria and abnormal renal function

This formula has the functions of nourishing the kidney and strengthening the spleen, nourishing blood and removing blood stasis, detoxification and reducing turbidity. It is mainly based on nourishing the kidney, strengthening the spleen and nourishing blood, and pays attention to removing stasis, detoxifying and reducing turbidity to promote the excretion of toxins in the body, but ignores dampness. Gujing, that is, the recovery of spleen and kidney qi and the solidification of fine substances are not enhanced from the source, and there is no targeted treatment for hematuria and proteinuria that often occur in patients with chronic kidney disease

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