Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Pleuropterus multiflorus extract and dipsacus asperoides extract for secreting insulin-like growth factor and promoting bone structure growth, and method for preparing same

A growth factor and bone growth technology, applied in the field of water-soluble extraction and refined products, can solve the problem of not having the conditions for commercialization, and achieve the effects of low price and convenient use

Active Publication Date: 2015-01-14
洪相根
View PDF7 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The IGF-1 secretion function of the composition in the above prior art is not ready for commercialization, and its function needs to be improved

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Pleuropterus multiflorus extract and dipsacus asperoides extract for secreting insulin-like growth factor and promoting bone structure growth, and method for preparing same
  • Pleuropterus multiflorus extract and dipsacus asperoides extract for secreting insulin-like growth factor and promoting bone structure growth, and method for preparing same
  • Pleuropterus multiflorus extract and dipsacus asperoides extract for secreting insulin-like growth factor and promoting bone structure growth, and method for preparing same

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0087] First, the dried Bai He Shou Wu is processed into powder or flakes with a size of 4 mm.

[0088] Then, in an extraction box equipped with a jacket, mix and dry 90° C. water of 8 times the weight of Radix Polygonum multiflorum and the processed Radix Radix Polygonum edulis, and stir for 8 hours to extract the water-soluble extract of Radix Fructus Radix. 70°C.

[0089] Then add 3 weight percent α-amylase of dried Radix Polygoni Radix to the extraction box containing the Radix Radix Polygoni Radix Extract, and set the fermentation temperature to 70° C. and the fermentation time to 6 hours to carry out the extraction of the Radix Radix Polygoni multiflori extract. Fermentation.

[0090] After the fermentation of the white Polygonum multiflorum extract is completed, the temperature of the extract is raised to above 95°C, and then cooling water is immediately injected into the jacket of the extraction box to rapidly cool the extracted fermentation liquid, thereby stopping t...

Embodiment 2

[0097] First, the dried chops are processed into powders or flakes with a size of 4 mm.

[0098] Then, in an extraction box equipped with a jacket, 90°C water of 8 times the weight of the dry discontinuity and the processed discontinuity were mixed together, and after stirring for 8 hours to extract the discontinuous water-soluble extract, the temperature of the extract was cooled to 70°C .

[0099] Then put the 3 weight percent α-amylase of the dry and discontinuous α-amylase into the extraction box equipped with the discontinuous extract, and set the fermentation temperature to 70° C. and the fermentation time to 6 hours to carry out the extraction of the discontinuous extract. Fermentation.

[0100] After the fermentation of the interrupted extract is completed, the temperature of the extract is raised to above 95°C, and then cooling water is immediately injected into the jacket of the extraction tank to rapidly cool the extract and fermentation, thereby stopping the activ...

experiment example 2

[0128] In this experimental example, experiments were carried out on the secretion ability of insulin-like growth factor (IGF-1) and the promoting effect of bone growth of the extracts of white Polygonum multiflorum and the water-soluble glycosides produced in the examples and comparative examples.

[0129] The analyzer used a microplate reader (LAB SYSTEM, USA), an enzyme immunoassay (rat IGF-1, catalogugue # DSL 10-2900, Diagnostic Systems Laboratories, USA), and the data analysis and statistical system used a Prism system ( ver, Graphpad Software Inc, USA).

[0130] As experimental animals, SD rats (Sprague Dawley rats) were used. For the long-term administration experiment, 3-week-old animals were used, and for the IGF-1 evaluation experiment, 9-week-old animals were used. All animals were male, and 30 animals were used in each experiment (10 animals in the control group, 10 animals in the example, and 10 animals in the comparative example). The feeding conditions of the...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The present invention relates to a purified aqueous extract material and to a method for preparing same, wherein the purified aqueous extract material includes, as a major ingredient, a glycoside ingredient of Pleuropterus multiflorus and Dipsacus asperoides which have the effect of secreting an insulin-like growth factor and promoting bone structure growth.

Description

technical field [0001] The present invention relates to a water-soluble extract and refined product which has the functions of enhancing insulin-like growth factor secretion and promoting bone growth, and the main components of Polygonum multiflorum and sudan glycosides, and a manufacturing method thereof. Background technique [0002] Growth hormone is a protein hormone secreted by the anterior pituitary gland of humans and animals. For humans, growth hormone consists of 191 amino acids, and in order to secrete it, the pituitary gland needs to be stimulated with a growth hormone secretion-promoting hormone. [0003] The main function of growth hormone in the body is to make peripheral tissues such as the liver produce insulin-like growth factor (Insulin-like Growth Factor-1, IGF-1), which acts on cartilage tissue to stimulate growth, and through metabolic effects Enhances protein synthesis, thereby increasing muscle mass while accelerating fatty acid oxidation, thereby redu...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/29A23L1/30A23L2/39A23L2/74A23L33/00
CPCA23V2002/00A23L1/3002A61K36/185A61K36/70A23L33/105A23V2200/306A23V2250/21A61K2300/00A61K2236/00A61P19/08A61P3/00A23L33/00A23L2/39A23L2/74A61K36/27A61K36/53
Inventor 洪相根
Owner 洪相根
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com