New use of Flatstem Milkvetch Seed
A technology of Shayuanzi and purpose, which is applied in the field of medicine, can solve the problem that there is no application for diabetic nephropathy, and achieve the effects of reducing the level of serum creatinine, improving the quality of life and reducing the excretion of proteinuria.
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[0018] The following describes but does not limit the present invention through the description of specific embodiments of the present invention.
[0019] The new application of the sand garden seed provided by the invention is to treat diabetic nephropathy, and obviously reduce the excretion of proteinuria.
[0020] 1. Pharmacological experiment
[0021] Shayuanzi is decocted according to the conventional method: Soak Shayuanzi for 30 minutes, decoct for 20 minutes, and the decoction is filtered and concentrated to contain 40mg of crude drug per 0.5ml.
[0022] The db / db mice were randomly divided into normal control group, model group and sand garden subgroup. 6 rats in each group, the Shayuanzi group was given the water decoction of Shayuanzi for 12 weeks, the normal control group and the model group were given the normal saline 0.5ml / 20g / day, and the Shayuanzi group was given the concentrated solution of Shayuanzi 0.5ml / 20g / day . The urinary albumin / creatinine ratio (AC...
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