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Traditional Chinese medicine composition and its extract and preparation for promoting liver disease recovery

A composition and extract technology, applied in the field of medicine, can solve the problems of high treatment cost, large toxic and side effects, etc., and achieve the effects of stable and controllable quality, low cost and definite curative effect

Inactive Publication Date: 2017-04-12
THE FIRST AFFILIATED HOSPITAL OF THIRD MILITARY MEDICAL UNIVERSITY OF PLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] In the face of liver disease, a common and extremely harmful disease, although modern medicine can effectively control the symptoms of liver disease, it has serious side effects and expensive treatment costs

Method used

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  • Traditional Chinese medicine composition and its extract and preparation for promoting liver disease recovery
  • Traditional Chinese medicine composition and its extract and preparation for promoting liver disease recovery
  • Traditional Chinese medicine composition and its extract and preparation for promoting liver disease recovery

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Embodiment 1, the preparation of the extract of the traditional Chinese medicine composition that promotes liver disease rehabilitation

[0028] Weigh 120g wolfberry, 120g yam, 60g hawthorn and 60g fried malt, decoct with 10 times the weight of water for 2.5 hours, filter, collect the extract, decoct the dregs with 8 times the weight of water for 1.5 hours, filter, The extracts are collected, combined twice, and concentrated to an extract with a relative density of 1.10-1.20 (60° C.), so as to obtain the extract of the traditional Chinese medicine composition for promoting liver disease recovery.

Embodiment 2

[0029] Embodiment 2, the preparation of the extract of the traditional Chinese medicine composition that promotes liver disease rehabilitation

[0030] Weigh 120g wolfberry, 120g yam, 60g hawthorn and 60g fried malt, decoct with 12 times the weight of water for 3 hours, filter, collect the extract, and decoct the dregs with 10 times the weight of water for 2 hours, filter, The extracts are collected, combined twice, concentrated to an extract with a relative density of 1.10-1.15 (60° C.), and the extract of the traditional Chinese medicine composition for promoting liver disease recovery is obtained.

Embodiment 3

[0031] Embodiment 3, the preparation of the extract of the traditional Chinese medicine composition that promotes liver disease rehabilitation

[0032] Weigh 140g of wolfberry, 140g of yam, 70g of hawthorn and 50g of fried malt, crush them into coarse powder, impregnate with 50vol% ethanol for 24 hours, percolate at a speed of 1-5ml per minute, and collect 1 times the total weight of medicinal materials The percolation liquid is recovered under reduced pressure to ethanol and concentrated to an extract with a relative density of 1.15-1.25 (60° C.) to obtain the extract of a traditional Chinese medicine composition for promoting liver disease recovery.

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Abstract

The invention discloses a traditional Chinese medicinal composition, an extract and a preparation for promoting rehabilitation of liver diseases. The traditional Chinese medicinal composition comprises the following traditional Chinese medicinal materials in parts by weight: 100-150 parts of fructus lycii, 100-150 parts of yam, 50-100 parts of hawthorn and 50-100 parts of fried malt, and is prepared by virtue of the following steps: decocting the traditional Chinese medicinal materials, or percolating and extracting the traditional Chinese medicinal materials with an ethanol aqueous solution, or performing reflux extraction to prepare an extract, thereby obtaining the extract of the traditional Chinese medicinal composition; preparing various preparations for clinical application from the extract and medicinal auxiliaries by virtue of a conventional medicinal preparation method, wherein four traditional Chinese medicinal materials which are affinal drug and diet are selected, the fructus lycii is a monarch drug, the yam is a ministerial drug, the hawthorn is an adjuvant drug, and the fried malt is a conductant drug, so that the formula is reasonable so as to play roles in nourishing liver, strengthening spleen, tonifying kidney, and activating blood circulation to remove stasis and eliminate toxicity. The traditional Chinese medicinal composition can be used for enhancing the immunity of patients with liver diseases and promoting endotoxin inactivation and inhibiting excessive release of body inflammatory factors, has the characteristics of exact curative effect, no toxic or side effect, stable and controllable quality, low cost and the like, and has excellent application prospect in the field of liver disease rehabilitation.

Description

technical field [0001] The invention belongs to the technical field of medicine and relates to a pharmaceutical composition. Background technique [0002] The improvement of modern people's living standards, the influence of various factors such as living habits, diet structure and environment, make the incidence of liver disease increase year by year, and present a younger trend, which has become a common concern and research focus in the medical field. Common liver diseases include hepatitis, cirrhosis, liver abscess, and primary liver cancer. Among them, hepatitis is mainly chronic hepatitis, which can be divided into chronic viral hepatitis, autoimmune hepatitis, drug-induced hepatitis, genetic diseases and other chronic hepatitis of unknown cause according to etiology. Viral hepatitis is most common with hepatitis B. According to statistics, more than 280 million people around the world carry hepatitis B surface antigen. China is a high-incidence area of ​​hepatitis ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8998A61P1/16A61P37/04
Inventor 陈剑鸿龚茜芬夏培元王显凤蔡永青孙凤军
Owner THE FIRST AFFILIATED HOSPITAL OF THIRD MILITARY MEDICAL UNIVERSITY OF PLA
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