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A model building method for rapid detection of borneol quality by near-infrared spectroscopy

A technology of near-infrared spectroscopy and model building, which is applied in the field of model building for rapid detection of borneol quality by near-infrared spectroscopy, can solve problems such as models without borneol quality, and achieve benefits to health, rapid detection, and prevention of fake and inferior products Effect

Active Publication Date: 2016-06-08
HENAN UNIV OF CHINESE MEDICINE
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Problems solved by technology

[0004] With the in-depth research on the chemical substances of traditional Chinese medicine, and the continuous development of optics, computer technology, chemometrics and near-infrared spectroscopy, it can be expected that near-infrared spectroscopy will have a broader application prospect in the field of traditional Chinese medicine analysis. The modernization of research and production plays an important role in promoting, but so far there is no public report on the use of near-infrared spectroscopy to establish a model for rapid detection of borneol quality to solve the quality detection of borneol

Method used

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  • A model building method for rapid detection of borneol quality by near-infrared spectroscopy
  • A model building method for rapid detection of borneol quality by near-infrared spectroscopy
  • A model building method for rapid detection of borneol quality by near-infrared spectroscopy

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Embodiment 1

[0034] 1) Collect borneol samples, collect the original spectrum, and obtain the average spectrum:

[0035] Collect 57 batches of borneol samples of different batch numbers, grind them into fine powder, pass through a 100-mesh sieve, and scan with a near-infrared spectrometer. The collection method of the near-infrared spectrometer is diffuse reflection, and the resolution is 8cm -1, the number of scans is 32, and the scan range is 12000-4000cm -1 , the ambient temperature is 18-28°C, and the scanning is carried out according to the above conditions. Each batch of samples is scanned repeatedly 6 times, the original spectrum is collected, and the average spectrum is calculated. The original NIR average spectrum of 57 batches of borneol fine powder is shown in figure 1 ;

[0036] 2) Establishment of the moisture consistency test model of borneol:

[0037] 2.1 Determination of borneol moisture, refer to the detection method under the item [Moisture] of Chinese Pharmacopoeia 201...

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Abstract

The invention relates to a method for establishing a model for rapidly detecting the quality of synthetic borneol through near infrared reflectance spectroscopy. By means of the method, the problems about detection of authenticity of synthetic borneol variety and quality of synthetic borneol can be effectively solved. According to the technical scheme, the method comprises steps as follows: 1), a synthetic borneol sample is collected, original spectrums are collected, and the average spectrum is acquired; 2), a synthetic borneol water content consistency check model is established; 3), a first synthetic borneol identification consistency model is established; 4), a second synthetic borneol identification consistency model is established; and 5), a quantitative analysis model of borneol in synthetic borneol is established. According to the method, rapid detection of the quality of synthetic borneol is effectively guaranteed, fake and shoddy products are prevented, large-scale industrial production of synthetic borneol and body health of people are facilitated, and the method has an actual application value, can accurately detect the authenticity and quality of synthetic borneol, is good in use effect and is an innovation method for detecting authenticity of synthetic borneol variety and quality of synthetic borneol.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a method for establishing a model for rapidly detecting the quality of borneol by near-infrared spectroscopy. Background technique [0002] Borneol, also known as machine-made borneol, is mainly composed of synthetic borneol, which is obtained by chemical synthesis from turpentine oil or camphor. It is a mixture of L-borneol and D-borneol (racemic borneol). Borneol is mostly used as "introduction and adjuvant" of Chinese patent medicines such as capsules, tablets, powders, and pills. Jue, qi depression violent Jue, middle-evil coma, aphtha carbuncle, red eyes and so on. Traditional Chinese medicine uses natural borneol as medicine, but because natural borneol is still limited by resources, the borneol most used in traditional Chinese medicine compound is synthetic borneol. In recent years, it has been found that adulterated products such as camphor, Glauber's salt, and alum often appear...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N21/359G01N21/3563
Inventor 段晓颖张晓东周艳梅陶明殷飞曹英杰刘瑞新
Owner HENAN UNIV OF CHINESE MEDICINE
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