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A whitening traditional Chinese medicine composition and its application in cosmetics

A technology of composition and cosmetics, applied in cosmetics, drug combinations, cosmetic preparations, etc., can solve the problems of hydroquinone, such as strong irritation, easy discoloration, and poor effect, and achieve good safety, good cost performance, and obvious inhibitory effect Effect

Active Publication Date: 2016-04-20
广州一一生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But there are many defects in these whitening agents, such as hydroquinone is very irritating, vitamin C and SOD are very unstable, kojic acid also has certain irritation and easy discoloration, arbutin has a single effect and poor effect, etc.

Method used

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  • A whitening traditional Chinese medicine composition and its application in cosmetics
  • A whitening traditional Chinese medicine composition and its application in cosmetics
  • A whitening traditional Chinese medicine composition and its application in cosmetics

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Extract (I) and preparation method of the Chinese medicine composition of embodiment 1

[0018] Take by weighing 38g of Chinese medicine raw materials Angelica sinensis, 24g of Baiji, 14g of desmodium, 10g of sage, and 14g of licorice, pulverize the above-mentioned Chinese medicine composition, sieve, and add a volume fraction of 50% according to the liquid-material mass ratio of 15:1 After soaking for 2 hours, use a high-pressure homogeneous extractor to extract at room temperature under a pressure of 80 MPa. After the extract is centrifuged, it is adsorbed with AB-8 macroporous resin, and the volume fraction is 30%, 60% , 90% ethanol for multiple elutions, collect the eluate, concentrate under reduced pressure to 50 g of the extract, then add 50 g of butanediol to dissolve, filter, and obtain the extract of 100 g of the Chinese medicine composition.

Embodiment 2

[0019] Extract (II) and preparation method of the Chinese medicine composition of embodiment 2

[0020] Take by weighing 40g of Chinese medicine raw materials Angelica sinensis, 28g of Baiji, 12g of desmodium, 10g of sage, and 10g of licorice, pulverize the above-mentioned Chinese medicine composition, sieve, and add a volume fraction of 60% according to the liquid-material mass ratio of 18:1 After soaking for 1.5 hours, use a high-pressure homogeneous extractor to extract at room temperature under a pressure of 75 MPa. After the extract is centrifuged, it is adsorbed with D101 macroporous resin, and the volume fractions are 20%, 50%, and 95% ethanol was eluted multiple times, the eluate was collected, concentrated under reduced pressure to 50 g of extract, then 50 g of butanediol was added to dissolve, filtered, and 100 g of the extract of the traditional Chinese medicine composition was obtained.

Embodiment 3

[0023] The preparation of embodiment 3 whitening skin care milk

[0024] Table 1 shows the formula of whitening skin care milk containing the traditional Chinese medicine extract composition, and the consumption of each substance is represented by mass fraction.

[0025] Table 1

[0026]

[0027] The preparation method of whitening skin care milk: cyclomethicone, cyclopentasiloxane, isopropyl palmitate, glyceryl caprylate, monoglyceride, stearic acid in the formula table , methylparaben, and propylparaben are mixed, heated to 80°C, melted and stirred evenly, and used as the oil phase; 1,2-propanediol, allantoin, traditional Chinese medicine extract composition, triethanolamine in the formula table , deionized water, heated to 85 ° C, stirred and dissolved evenly, as the water phase. Add the oil phase and water phase to the emulsification pot, stir evenly, emulsify and homogenize for 6 minutes, stir and cool to 50°C, add essence, stir evenly, cool to 38°C, it is whitening ...

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Abstract

The invention discloses a traditional Chinese medicine composition with a whitening effect. The traditional Chinese medicine composition is characterized by consisting of the following raw materials: 30-50 percent of Chinese angelica, 25-35 percent of rhizoma bletillae, 10-15 percent of Lysimachia christinae Hance, 10-15 percent of sage and 5-10 percent of liquorice. The preparation method comprises the following steps: grinding the traditional Chinese medicine composition, screening, adding an extraction solvent according to a liquid material mass ratio of 10:1-30:1, soaking for 1-2 hours, performing normal temperature extraction under the pressure of 50-100MPa by using a high-pressure homogenizing extractor, performing centrifugal separation on the extracting solution, adsorbing by using a macroporous resin, repeatedly eluting by using 10-95 percent of ethanol, collecting the eluent, performing reduced pressure concentration until the mass ratio of the extracting solution to the traditional Chinese medicine is 1:0.5-1:10; and adding butanediol with the same mass as the extracting concentrate, filtering and preparing the extract of the traditional Chinese medicine composition. The extract of the traditional Chinese medicine composition prepared by the method has the effects of strongly inhibiting melanogenesis, eliminating free radicals and realizing sun protection, is used in cosmetics and achieves the effect of whitening the skin.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to the application of a whitening traditional Chinese medicine composition and its extract in cosmetics. Background technique [0002] Since ancient times, whiteness has been regarded as beauty in China. As the saying goes, "one white covers all ugliness", fair skin is the lifelong pursuit of all women. In addition to natural dark skin, from the perspective of traditional Chinese medicine, not white is often a manifestation of poor health, imbalance of viscera and blood, and a sub-healthy state, often showing symptoms such as chloasma and freckles on the face. For the treatment of facial spots, there are methods such as laser or intense pulsed light therapy, external drug therapy, etc.; wherein laser or intense pulsed light therapy is very harmful to the skin and is not commonly used; cosmetic whitening is the most commonly used method at present. [0003] There are maj...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/97A61K36/898A61Q19/02A61Q19/08A61Q17/04A61P17/18
Inventor 龚盛昭龚德明何远伦
Owner 广州一一生物技术有限公司
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