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Medicine for treating prostatitis and preparation method thereof

A technology for prostatic hyperplasia and drugs, which is applied in the directions of pharmaceutical formulas, drug combinations, and medical preparations containing active ingredients, etc., can solve problems such as difficult to determine prostatitis, difficult clinical classification, and emphasis on antibiotic drug treatment.

Active Publication Date: 2014-07-02
连云港市赣榆区综合检验检测中心
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The number of pathogens detected by conventional methods is only a minority, and it is not easy to determine which patients are suffering from non-bacterial prostatitis
Evidence of autoimmunity can be detected in some patients, but accurate clinical classification is difficult
The clinical manifestations of this disease are complex symptom groups, the commonly used diagnostic methods in the past are not detailed enough, and the treatment has a certain degree of blindness, often emphasizing the treatment of antibiotics

Method used

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  • Medicine for treating prostatitis and preparation method thereof
  • Medicine for treating prostatitis and preparation method thereof
  • Medicine for treating prostatitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Example 1: Experimental research on general anti-inflammatory effect

[0024] (1) Effect on cotton ball granuloma in rats

[0025] 1. Purpose of the test: To observe the inhibitory effect on rat connective tissue hyperplasia induced by cotton ball implantation.

[0026] , test drug

[0027] The Chinese medicine composition of the present invention's implementation 5 is mixed with distilled water to a concentration of 18% before use.

[0028] Hydrocortisone, specification 5mg / ml

[0029] 3. Test animals

[0030] Fifty adult healthy SD male rats with a body weight of 190±20 g were selected.

[0031] ,experiment method

[0032] Fifty healthy SD male rats were randomly divided into 5 groups, 10 in each group. Respectively: normal control group, positive control group (with hydrocortisone intramuscular injection 5mg / kg), large dose group of Chinese medicine composition of the present invention (4.0g crude drug kg -1 ); Chinese medicine composition ...

Embodiment 2

[0059] Example 2: Effects on Rat Hemorheology

[0060] 1. The purpose of the experiment: This experiment mainly explores the effect on the hemorheology of rats.

[0061] , test drug

[0062] The Chinese medicine composition of the present invention's implementation 7 is mixed with distilled water to a concentration of 18% when used.

[0063] Positive drug: Qianliexin Capsules, prepared with distilled water to a concentration of 18% before use.

[0064] Testosterone propionate, specification: 25mg / ml, diluted with olive oil to a concentration of 10mg / ml before use.

[0065] , experimental animals and experimental materials

[0066] Male SD rats, 60, weighing 237.9±30.1 grams. Hemorheometer: Beijing Prism Instrument Center; Model: LBY-N 6

[0067] 4. Experimental method

[0068] A total of 60 healthy male SD rats were selected, and 10 were randomly selected as the normal group. The other 50 were anesthetized with 4% chloral hydrate, and the bilateral test...

Embodiment 3

[0080] Embodiment 3: Effect on rat experimental benign prostatic hyperplasia pathological model

[0081] 1. Purpose of the experiment : This experiment mainly discusses the curative effect of treating benign prostatic hyperplasia.

[0082] , test drug

[0083] Test drug:

[0084] The Chinese medicine composition of the present invention's implementation 8 is mixed with distilled water to a concentration of 18% before use.

[0085] Positive drug: Qianliexin Capsules, prepared with distilled water to a concentration of 18% before use.

[0086] Testosterone Propionate: Specification: 25mg / ml.

[0087] 3. Experimental animals

[0088] SD rats, male, 60, body weight 238.1±30.3.

[0089] ,experimental method

[0090] A total of 60 healthy male SD rats were selected, and 10 were randomly selected as the normal group. The other 50 were anesthetized with 4% chloral hydrate, and the bilateral testes were removed under aseptic conditions, and then the skin was sutu...

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Abstract

The invention belongs to traditional Chinese medicine field, relates to a traditional Chinese medicine composition, in particular relates to a traditional Chinese medicine composition for treating prostatitis and a preparation method and a usage thereof. The traditional Chinese medicine composition is prepared from the following raw materials in part by weight: 1 to 8 parts of ligusticum, 1 to 8 parts of biond magnolia flower, 1 to 8 parts of cynomorium songaricum, 1 to 8 parts of dodder, 1 to 8 parts of flatstem milkvetch seed, 1 to 8 parts of raspberry, 1 to 8 parts of cherokee rose fruit, 1 to 8 parts of long pepper, 1 to 8 parts of clove, 1 to 8 parts of polygala root, 1 to 8 parts of obscured homalomena rhizome, and 1 to 8 parts of juncus. The traditional Chinese medicine composition is capable of treating prostatitis, prostatic hyperplasia, diabetic nephropathy and renal insufficiency.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine and relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating prostatitis, a preparation method and application thereof. Background technique [0002] Prostatitis is a common disease of the male reproductive system. Among male urological patients, the group under 50 years old occupies the first place, and the group over 51 years old occupies the second place. Its incidence rate is as high as 6%. Prostatitis accounted for 8% of the population. Its etiology and pathogenesis have not been fully elucidated. Only a minority of pathogens are detected by conventional methods, and it is not easy to determine which patients are suffering from non-bacterial prostatitis. Evidence related to autoimmunity can be detected in some patients, but it is difficult to carry out accurate clinical classification. The clinical manifesta...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/888A61P13/08A61P3/10A61P13/12
Inventor 赵永君范立王乐
Owner 连云港市赣榆区综合检验检测中心
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