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Compound salidroside oral liquid used for livestock and poultry, and preparation method thereof

A technology of sedroside oral liquid and salidroside, which is applied in the field of drug preparation to achieve the effects of less pollution, no residual price, and easy industrialization

Inactive Publication Date: 2014-06-04
TIANJIN JUNHEXIN TECH DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Salidroside extraction technology has been used in human medicine, but veterinary medicine has not yet been used. Ginseng stem and leaf saponin granules have not been developed and produced in China. Therefore, there is an urgent need to develop a series of new sources of traditional Chinese medicine and drugs for new indications. To make up for the gap in the domestic veterinary drug market in traditional Chinese medicine, to open up a new way to enhance the immunity and disease resistance of livestock and poultry

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0015] Embodiment 1: The compound salidroside oral liquid of the present invention comprises the following components according to the ratio in parts by weight: 2 parts of salidroside; 3 parts of total saponins from ginseng stems and leaves; 1 part of purple daisy extract; 804 parts of Tween ; 15 parts of ethanol, 50 parts of water for injection. The preparation method of compound salidroside oral liquid comprises the following steps:

[0016] (1) Add rhodiola rosea, total saponins from ginseng stems and leaves, and purple daisy extract to 1 / 2 of the total amount of ethanol, and stir until completely dissolved;

[0017] (2) Add Tween to 1 and stir for 5 minutes;

[0018] (3) Add remaining amount of ethanol to 2 and stir;

[0019] (4) Add water for injection to the full amount, and add 0.5% activated carbon for injection (g / V) under stirring to obtain the compound salidroside oral liquid.

Embodiment 2

[0020] Embodiment 2: The compound salidroside oral liquid of the present invention comprises the following components according to the ratio in parts by weight: 3 parts of salidroside; 5 parts of total saponins from ginseng stems and leaves; 2 parts of purple daisy extract; 806 parts of Tween ; 20 parts of ethanol, 60 parts of water for injection. The preparation method of compound salidroside oral liquid comprises the following steps:

[0021] (1) Add rhodiola rosea, total saponins from ginseng stems and leaves, and purple daisy extract to 1 / 2 of the total amount of ethanol, and stir until completely dissolved;

[0022] (2) Add Tween to 1 and stir for 5 minutes;

[0023] (3) Add remaining amount of ethanol to 2 and stir;

[0024] (4) Add water for injection to the full amount, and add 0.5% activated carbon for injection (g / V) under stirring to obtain the compound salidroside oral liquid.

Embodiment 3

[0025] Embodiment 3: The compound salidroside oral liquid of the present invention comprises the following components according to the ratio in parts by weight: 4 parts of salidroside; 8 parts of total saponins from ginseng stems and leaves; 3 parts of purple daisy extract; 8010 parts of Tween ; 25 parts of ethanol, 75 parts of water for injection. The preparation method of compound salidroside oral liquid comprises the following steps:

[0026] (1) Add rhodiola rosea, total saponins from ginseng stems and leaves, and purple daisy extract to 1 / 2 of the total amount of ethanol, and stir until completely dissolved;

[0027] (2) Add Tween to 1 and stir for 5 minutes;

[0028] (3) Add remaining amount of ethanol to 2 and stir;

[0029] (4) Add water for injection to the full amount, and add 0.5% activated carbon for injection (g / V) under stirring to obtain the compound salidroside oral liquid.

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Abstract

The invention discloses a compound salidroside oral liquid used for livestock and poultry, and a preparation method thereof. The compound salidroside oral liquid comprises, by weight, 2 to 4 parts of salidroside, 3 to 8 parts of ginseng stem and leaf total saponins, 1 to 3 parts of purple daisy extractive, 4 to 10 parts of tween 80, 15 to 25 parts of ethanol, and 50 to 75 parts of injection water. The compound salidroside oral liquid is mainly used for treating bacterial infection, escherichia coli infection, respiratory diseases, virus infection, and mixed infection of livestock and poultry in adjacent periods of livestock and poultry breeding, is safe and green, and is high in efficiency; no residue is left; and cost is moderate. Significant efficiency of the compound salidroside oral liquid in treating escherichia coli infection and respiratory diseases of livestock and poultry reaches 92.0%, and effective ratio reaches 96.0%. The compound salidroside oral liquid is reasonable in compatibility, high in clarity and oral bioavailability, and is convenient for industrialization; and dust and pollution are less.

Description

technical field [0001] The invention belongs to the technical field of medicine preparation, in particular to a compound salidroside oral liquid and a preparation method thereof. Background technique [0002] With the rapid development of China's livestock and poultry breeding industry and the continuous development of veterinary drug research, the application of antibiotics in the treatment of various diseases and infections of livestock and poultry has become common, but due to the abuse of antibiotics and cross-resistance, the immunity of livestock and poultry bodies has declined , the decline in production capacity, and the residue of drugs have caused some animal-derived foods to directly cause harm to people's health. With the use of precious traditional Chinese medicines, some rare Chinese medicinal materials have become expensive and protected. China is a big country of traditional Chinese medicine, with With a history of more than 2,000 years, how to better use Chin...

Claims

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Application Information

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IPC IPC(8): A61K36/258A61K36/41A61K9/08A61P31/04A61P11/00A61P31/12A61K31/7032
Inventor 裴毅
Owner TIANJIN JUNHEXIN TECH DEV
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