Test method of banned azo-dye in cigarette paper

Abstract

The invention discloses a test method of a banned azo-dye in cigarette paper and belongs to the technical field of physical and chemical inspection of harmful substance residues in lined paper, tipping paper and carton packaging paper for cigarettes. The test method is characterized by comprising the following steps: cutting a cigarette paper sample, adding a reduction solution, reducing an azo substance into aromatic amine by sodium hydrosulfite in a citric acid buffer solution, extracting aromatic amine from the solution by a liquid-liquid extraction method, concentrating, redissolving by methanol, testing by a liquid chromatography-tandem mass spectrometry combined instrument, and quantifying by an internal standard method. According to the method, the deficiencies of a sample treatment method in the prior art are overcome, and a sample pre-treatment method and instrument test conditions are optimized for the tipping paper, the lined paper and the carton packaging paper for the cigarettes; as a solid-phase extraction column does not need to be passed, cumbersome purification and concentration steps such as rotary evaporation are not required, and the method has the advantages of accuracy for operation, high recovery rate, quickness, simplicity, convenience, high sensitivity and the like.

Description

[0001] technical field [0002] The invention belongs to the technical field of physical and chemical inspection of harmful substance residues in inner liner paper, tipping paper and carton wrapping paper for cigarettes, and mainly relates to the determination technology of azo dyes in inner liner paper, tipping paper and carton wrapping paper for cigarettes Specifically, azo substances are reduced to aromatic amines by sodium dithionite in a citric acid buffer solution, and then the aromatic amines in the solution are extracted by liquid-liquid extraction. Determination was performed with a combined instrument, and the internal standard method was used for quantification. [0003] Background technique [0004] In the production process of cigarette paper, including lining paper, tipping paper, carton wrapping paper, etc., it is necessary to add various chemicals such as bleaching agents, processing aids, printing inks, antiseptics, etc. Improve its packaging performance a...

AI Technical Summary

Problems solved by technology

These methods all require cumbersome pretreatment processes, and the recovery rate of some aromatic amines is low

GC and HPLC methods have low requirements on instruments and equipment, but are easily affected by impurity interference, resulting in false positives

Moreover, aromatic amines are highly polar and have poor thermal stability. When analyzed by GC-MS method, the sensitivity is not high and the chromatographic peak shape is poor.

Images