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Natural medicine composition

A technology of natural medicines and compositions, applied in drug combinations, antitumor drugs, pharmaceutical formulations, etc.

Inactive Publication Date: 2014-04-02
张宗升
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that has the effect of alleviating diarrhea against cancer chemotherapy

Method used

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  • Natural medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0030] The first step: preparation of various extracts

[0031] (1) Preparation of the concentrated extract of Phellodendron Schisandra decocted in water

[0032] According to the compatibility ratio of 1-5:1, take Cortex Phellodendron and Schisandra chinensis, soak in distilled water, heat and decoct, filter, add distilled water to the dregs, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate, and use an ultrafiltration membrane Filter, dry under reduced pressure, that is.

[0033] (2) Preparation of Phellodendron Phellodendri Ethyl Acetate Extract

[0034] Phellodendron cortex is crushed, soaked in 95% alcohol for 3 times, combined with ethanol extract, brown extract obtained by distillation under reduced pressure, dispersed in water, extracted with water, diethyl ether and ethyl acetate in sequence, part of ethyl acetate is distilled under reduced pressure, and dried to obtain phellodendron acetic acid ethyl ester extract.

[0035] (3) ...

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Abstract

The invention relates to a natural medicine composition which comprises concentration extracts obtained by decocting golden cypress and Chinese magnoliavine fruit by using water, a golden cypress ethyl acetate extract and Chinese magnoliavine fruit polysaccharide at a ratio of (1-6):(5-7):(3-7). The natural medicine composition has a treatment effect on cancer chemotherapy-induced diarrhea.

Description

technical field [0001] The present invention relates to a kind of natural medicine composition, more specifically relate to a kind of natural medicine composition that is composed of Phellodendron Schizandra decoction concentrated extract, Phellodendron chinensis ethyl acetate extract and Schisandra polysaccharide, the preparation method of the natural medicine composition and Use of the natural medicine composition for preparing medicines for reducing cancer chemotherapy-associated diarrhea. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs are cytotoxic anti-tumor drugs, which can cause diarrhea and other side effects when used alone or in combination. Diarrhea after tumor chemotherapy is also called c...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/79A61K36/756A61P35/00A61P1/12A61K31/715
Inventor 张宗升
Owner 张宗升
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