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Application of jaceosidin in preparation of drugs used for treating or preventing chronic kidney injury

A technology of palm cyanidin and chronic kidney injury, applied in the field of application of palm cyanidin in the preparation of medicines for treating or preventing chronic kidney injury

Active Publication Date: 2014-03-26
陕西映诺嘉生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Palm cyanidin is a single compound extracted from Artemisia argyi [Tang Shengan, Sun Liang, Zhai Huiyuan, Duan Hongquan, Zhang Yanwen. Research on the chemical constituents of Artemisia argyi. Journal of Tianjin Medical University, 2011, 17(4): 461-463.], Palm cyanidins have anti-inflammatory effects [Clavin M, Gorzalczany S, Macho A, E, Ferraro G, Acevedo C, Martino V. Anti-inflammatory activity of flavonoids from Eupatorium amottianum. JEthnopharmaco1.2007; 112(3): 585-589.], but brown cyanidin in the preparation of prevention or treatment of chronic kidney injury Pharmacological effects on renal fibrosis have not been reported

Method used

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  • Application of jaceosidin in preparation of drugs used for treating or preventing chronic kidney injury
  • Application of jaceosidin in preparation of drugs used for treating or preventing chronic kidney injury
  • Application of jaceosidin in preparation of drugs used for treating or preventing chronic kidney injury

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Effect test

preparation example 1

[0017] Palm cyanidin is prepared according to Preparation Example 1

[0018] Glutathione (Shandong Luye Pharmaceutical Co., Ltd., specification: 300mg / bottle, batch number: 20120706)

[0019] Creatinine and blood urea nitrogen kit (Beijing Zhongsheng Technology Company, batch number: 120606)

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PUM

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Abstract

The invention relates to application of jaceosidin in preparation of drugs used for treating or preventing chronic kidney injury, specifically to application of jaceosidin in preparation of drugs used for treating or preventing chronic renal failure, renal fibrosis and diabetic nephropathy. In the above-mentioned application, the dosage range of applied jaceosidin is 10 to 500 mg, preferably, 10 to 250 mg. Jaceosidin exists in the form of a tablet, a pill, a granule, a capsule, syrup or the like, preferably, the tablet.

Description

technical field [0001] The present invention relates to the application of palm cyanidin in the preparation of medicine for treating or preventing chronic kidney injury, in particular to the application of palm cyanidin in the preparation of medicine for treating or preventing chronic renal failure, renal fibrosis and diabetic nephropathy . Background technique [0002] Folium Artemisiae Argyi is derived from the dried leaves of Artemisia argyi Levl. et Vant., which is a commonly used clinical traditional Chinese medicine. Palm cyanidin is a single compound extracted from Artemisia argyi [Tang Shengan, Sun Liang, Zhai Huiyuan, Duan Hongquan, Zhang Yanwen. Research on the chemical constituents of Artemisia argyi. Journal of Tianjin Medical University, 2011, 17(4): 461-463.], Palm cyanidins have anti-inflammatory effects [Clavin M, Gorzalczany S, Macho A, E, Ferraro G, Acevedo C, Martino V. Anti-inflammatory activity of flavonoids from Eupatorium amottianum. JEthnopharmaco1...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/352A61P13/12A61P3/10
Inventor 蒋王林亢泽春栾海云许勇
Owner 陕西映诺嘉生物科技有限公司
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