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Traditional Chinese medicine preparation for controlling pullorosis salmonellosis and preparation method thereof

A technology of Salmonella and traditional Chinese medicine preparations, which is applied in the direction of antibacterial drugs, pharmaceutical formulas, and medical preparations containing active ingredients. It can solve the problems of low active ingredients, instability, and unstable comprehensive curative effect, and achieve uniform particles and consistent color. , quality controllable effect

Inactive Publication Date: 2014-03-12
SICHUAN AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the application of traditional veterinary Chinese medicine, there are still many problems in the wide application of veterinary Chinese herbal medicine in my country, such as the large volume of compound Chinese medicine, low and unstable active ingredients, and unstable comprehensive curative effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Preparation of Polygonum cuspidatum extract: Take Polygonum cuspidatum and extract with 5 times the amount of 60% ethanol under reflux for 2 times, each time for 1.5 hours, the extraction temperature is 95°C, combine the extracts, concentrate and dry under reduced pressure to obtain Polygonum cuspidatum extract.

[0025] Preparation of myrobalan extract: Take myrobalan and extract it twice with 20 times the amount of distilled water, each time for 1.5 hours, the extraction temperature is 100°C, combine the extracts, concentrate and dry under reduced pressure to extract myrobalan thing.

[0026] The preparation of viola radix extract: take viola chinensis and grind it with 20 times the amount of 60% ethanol, soak it for 24 hours, ultrasonically extract it for 45 minutes, filter, repeat the extraction of the filter residue 1-2 times, combine the extracts, concentrate and dry under reduced pressure to obtain Viola extract.

[0027] Mix Polygonum cuspidatum extract, Myroba...

Embodiment 2

[0029] Preparation of Polygonum cuspidatum extract: take Polygonum cuspidatum and extract with 8 times the amount of 70% ethanol under reflux for 3 times, each time for 1.5 hours, the extraction temperature is 80°C, combine the extracts, concentrate and dry under reduced pressure to obtain Polygonum cuspidatum extract.

[0030] Preparation of myrobalan extract: Take myrobalan and extract it twice with 15 times the amount of distilled water, 1.5 hours each time, the extraction temperature is 100°C, combine the extracts, concentrate and dry under reduced pressure to extract myrobalan things.

[0031] The preparation of viola radix extract: take Viola radix and crush it with 15 times the amount of 70% ethanol, soak it for 24 hours, ultrasonically extract it for 30 minutes, filter, repeat the extraction of the filter residue 1-2 times, combine the extracts, concentrate and dry under reduced pressure to obtain Myrobalan extract.

[0032] Mix Polygonum cuspidatum extract, Myrobalan...

Embodiment 3

[0034] Preparation of Polygonum cuspidatum extract: After crushing Polygonum cuspidatum, reflux extraction with 10 times the amount of 80% ethanol for 3 times, 1.5 hours each time, extraction temperature was 90°C, combined extracts, concentrated and dried under reduced pressure to obtain Polygonum cuspidatum extract.

[0035] Preparation of myrobalan extract: take chebula and extract it twice with 15 times the amount of distilled water, each time for 1.5 hours, the extraction temperature is 100°C, combine the extracts, concentrate and dry under reduced pressure to obtain the extract of myrobalan .

[0036] The preparation of viola radix extract: take viola chinensis and grind it with 15 times the amount of 80% ethanol, soak it for 24 hours, ultrasonically extract it for 45 minutes, filter, repeat the extraction of the filter residue 1-2 times, combine the extracts, concentrate and dry under reduced pressure to obtain Myrobalan extract.

[0037] Mix Polygonum cuspidatum extrac...

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PUM

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Abstract

The invention provides a traditional Chinese medicine preparation for controlling pullorosis salmonellosis. The traditional Chinese medicine preparation is characterized by being prepared from the following extracts in parts by weight: 3 to 5 parts of polygonum cuspidatum extract, 1 to 2 parts of fructus chebulae extract, and 1 to 2 parts of herba violae extract. The prepared traditional Chinese medicine compound particles are uniform in size, consistent in color and luster, and free of moisture adsorption, caking, deliquescence and other phenomena, meet the requirements of Chinese Pharmacopoeia, and are controllable in quality. The pharmacodynamics study shows that the traditional Chinese medicine preparation can be used for preventing and treating pullorosis salmonellosis.

Description

technical field [0001] The invention relates to a traditional Chinese medicine compound preparation for preventing and treating pullorum salmonellosis and a preparation method thereof. Background technique [0002] Salmonellosis is a general term for various animal diseases caused by Salmonella bacteria. Salmonella is a large group of parasites in the intestinal tract of humans and animals. Most Salmonella are pathogenic to humans and animals, mainly through the digestive tract. The clinical manifestations are different from animals, and it is one of the main pathogens of human food poisoning. Salmonella most often invades juvenile and young animals, causing sepsis, gastroenteritis and other local inflammation of tissues, and causing sporadic or localized infection in adult animals. Salmonellosis, pregnant female animals with septicemia can show abortion, such as chickens, pigs, horses, sheep, dogs, etc. are all susceptible animals. [0003] The irrational use of antibiotic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/86A61K9/16A23K1/16A23K1/18A61P31/04
CPCY02A50/30
Inventor 殷中琼贾仁勇代如意徐娇李莉宋旭
Owner SICHUAN AGRI UNIV
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