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Antimicrobial physical method

An anti-microbial and anti-microbial film technology, applied in the direction of resisting vector-borne diseases, electrotherapy, anti-inflammatory agents, etc., can solve the problem of bacterial biofilms without preventive and therapeutic effects.

Active Publication Date: 2014-02-12
NMS TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] An object of the present invention is to provide a physical antimicrobial method, solve the problem of drug-resistant bacteria caused by current antibacterial drugs by physical methods, and solve the problem that classical antibacterial methods have no preventive and therapeutic effects on bacterial biofilms

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0083] The schematic diagram of embodiment 1 physical antimicrobial film

[0084] figure 1 A schematic diagram of a physical antimicrobial membrane according to one embodiment of the present invention is shown. figure 1 1 is the body surface, which can be skin (including mucous membrane) or various other items, figure 1 2 is a physical antimicrobial film, which has a positive charge and is glued or adsorbed to the surface of 1. figure 1 Middle 3 is optional other functional films.

[0085] It should be understood that although the physical antimicrobial film is shown as a planar configuration, it can be of various curved configurations.

Embodiment 2

[0086] The preparation of embodiment 2 organosilicon double quaternary ammonium salts

Embodiment 2a

[0087] The preparation of embodiment 2a organosilicon double quaternary ammonium salt 1

[0088]

[0089] Silicone double quaternary ammonium salt 1, where R, R' is C 12 h 25 , X - for Cl -

[0090] (1) Synthesis of double long-chain alkyl quaternary ammonium salts with hydroxyl-containing linking groups

[0091] Add 0.2 mol of dodecyldimethylamine and 40 ml of isopropanol-water mixed solvent (the volume ratio of isopropanol to water is 10:1) into the three-necked bottle. The contents were heated to 50° C. with stirring, then 0.21 mol of epichlorohydrin was added dropwise thereto, and the reaction was allowed to proceed for 3 hours to obtain glycidyldodecyldimethylammonium chloride.

[0092] Another 0.2 mol of dodecyldimethylamine was slowly added to the reaction mixture obtained in the previous step, and at the same time, 10% hydrochloric acid was added dropwise to keep the pH value of the reaction mixture at 9. After the addition was complete, the reaction mixture w...

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Abstract

The invention discloses an antimicrobial physical method. An effect of killing or inhibiting microorganisms can be realized when the antimicrobial physical method is applied to a human body, or an animal or the surface of an object. The antimicrobial physical method is safe to the human body, and drug resistance caused by antibacterial agents can not be produced.

Description

technical field [0001] The present invention relates to an anti-microbial physical method, in particular to an anti-microbial positively charged nano film and the anti-microbial physical method using the nano film on human body and other objects. Background technique [0002] Physical antimicrobial method is a traditional method used to prevent the infection and spread of pathogenic microorganisms. Common physical antimicrobial methods include high temperature, high pressure and ultraviolet sterilization. However, these traditional physical antimicrobial methods are harmful when used directly on the human body, so they are basically used for the disinfection of articles and spaces, and are not used on the human body. Antimicrobial methods for the human body generally rely on various antimicrobial drugs. [0003] At present, the antimicrobial methods applied to the human body are all chemical and biological methods, in which antimicrobial drugs are antimicrobial by hinderin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K45/00A61K31/695A61K9/70A61K9/14A61P31/00A61L2/232A61L2/16A61L101/32
CPCA61K31/695A61K9/14A61N1/40A61K9/70A61N1/00A61L2/16A61K45/06A61L2/232A61K9/7015F04C2270/0421A61P17/00A61P17/02A61P29/00A61P31/00A61P31/02A61P31/04A61P31/10A61P31/12A61P31/14A61P31/18A61P31/20A61P31/22A61P33/00A61P35/00A61P41/00A61P7/04C07F7/025A61K2300/00A61K9/16A61K31/14Y02A50/30A01N55/00
Inventor 蔡友良
Owner NMS TECH
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