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Application of fructus forsythia extract in preparation of health food or cosmetic with UVA (Ultraviolet A) radiation resistance and anti-aging effect

A technology of forsythia extract and health food, applied in the direction of food ingredients containing natural extracts, cosmetics, cosmetic preparations, etc., can solve the problems of anti-inflammation and anti-aging research that have not been found yet, and achieve high extraction efficiency, The effect of low preparation cost and full utilization of resources

Active Publication Date: 2014-02-12
INFINITUS (CHINA) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] Because radiation causes inflammation, and inflammation can cause aging, at present, plant forsythia extract is used in various medicine and health care, but the research on using forsythia extract for anti-radiation, anti-inflammation and anti-aging has not yet been completed. Find

Method used

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  • Application of fructus forsythia extract in preparation of health food or cosmetic with UVA (Ultraviolet A) radiation resistance and anti-aging effect
  • Application of fructus forsythia extract in preparation of health food or cosmetic with UVA (Ultraviolet A) radiation resistance and anti-aging effect
  • Application of fructus forsythia extract in preparation of health food or cosmetic with UVA (Ultraviolet A) radiation resistance and anti-aging effect

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] The preferred preparation method of the forsythia extract provided in this embodiment comprises the following steps:

[0044] A: Pretreatment: wash the raw material forsythia with water, crush it, sieve it to 30-60 mesh, and weigh 1 kg;

[0045] B: Extraction: Ultrasonic extraction with 8-10 kg of ethanol aqueous solution with a volume percentage of 40-80% ethanol twice, each time for 20-40 minutes, filtered, combined extracts, and concentrated extracts to obtain 3-5 kg ​​concentrated Liquid, add 6-20 kilograms of water to dilute the concentrated solution in the concentrated solution, filter, obtain 9-25 kilograms of B filtrate;

[0046] C: Sample loading: put the filtrate from B onto a PIPO-02 (separation material weighing 200-600 grams) macroporous resin separation column with a column volume of 200-600 ml, the same volume and a double-column section connected in series;

[0047] D: Separation, elute 800-4800 ml with 5-12% ethanol aqueous solution by volume, remove t...

Embodiment 2

[0050] The preferred preparation method of the forsythia extract provided in this embodiment comprises the following steps:

[0051] A: Pretreatment: wash the raw material forsythia with water, crush it, sieve it to 30-60 mesh, and weigh 10 kg;

[0052] B: Extraction: Ultrasonic extraction with 80-100 kg of ethanol aqueous solution with a volume percentage of 40-80% ethanol twice, each time for 20-40 minutes, filtered, combined extracts, concentrated to obtain 30-50 kg of concentrated solution, in Add 60-200 kg of water to the concentrated liquid to dilute the concentrated liquid, and filter to obtain 90-250 kg of B filtrate;

[0053] C: Sample loading: put the filtrate from B onto a PIPO-02 separation column with a column volume of 2000-6000 ml (the weight of the separation material is 2000-6000 grams), the same volume and a double-column section connected in series;

[0054] D: Separation, elute 8,000-48,000 ml with ethanol aqueous solution with ethanol volume percentage of...

Embodiment 3

[0057] The preferred preparation method of the forsythia extract provided in this embodiment comprises the following steps:

[0058] A: Pretreatment: wash the raw material forsythia with water, crush it, sieve it to 30-60 mesh, and weigh 100 kg;

[0059] B: Extraction: Use 800-1000 kg of 40-80% ethanol to ultrasonically extract twice, each time for 20-40 minutes, filter, combine, concentrate to obtain 300-500 kg of extract, add 600-2000 kg of water to dilute the extract, and filter , obtain 900-2500 kilograms of B filtrate;

[0060] C: Sample loading: put the filtrate from B onto a PIPO-02 separation column with a column volume of 2000-6000 ml (the weight of the separation material is 2000-6000 grams), the same volume and a double-column section connected in series;

[0061] D: Separation, elute 80-480 liters with 5-12% ethanol, remove the former impurities, elute with 25-45%% ethanol water, collect 40-240 liters, and obtain D separation liquid;

[0062] E: Concentration and...

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Abstract

The invention discloses application of fructus forsythia extract in preparation of health food or a cosmetic with UVA (Ultraviolet A) radiation resistance and anti-aging effect. The fructus forsythia extract in the invention has UVA radiation resistance, can remarkably alleviate cellular damages caused by UV (Ultraviolet) radiation, has obvious inhibiting effect on expression of macrophage inflammatory factors at the same time, and can bring anti-inflammatory and anti-ageing effect into play. According to the application, UV radiation resistance and anti-ageing effect of the fructus forsythia extract can be illuminated from cellular and molecular cell. Besides, the invention further discloses an optimized preparation method of the fructus forsythia extract with the UVA radiation resistance and the anti-ageing effect.

Description

technical field [0001] The invention belongs to the technical field of forsythia, in particular to the application of forsythia extract in preparing health food or cosmetics with anti-UVA radiation and anti-aging effects. technical background [0002] In recent years, active ingredients derived from plants have been increasingly used in compositions for the purposes of medicine, treatment and beauty. [0003] Aging is a physiological phenomenon, and its physiological manifestation is the decline of the functions of various organs, leading to the occurrence of various aging diseases. And the most intuitive evidence is the aging of the skin. At the molecular level, it is manifested as cellular senescence, which is a gradual event that accompanies the aging of the body. Aging not only leads to the degradation of the body's physiological functions, but also the gradual degradation of the body's immune system. In the process of human aging, not only due to its own physiologica...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L1/30A61K8/97A61Q19/08A61Q17/04A23L33/105
CPCA23L33/105A23V2002/00A61K8/97A61Q17/04A61Q19/08A23V2200/30A23V2200/302A23V2250/21
Inventor 赵宏伟王一飞吴志韻袁晓邹士玉马忠华
Owner INFINITUS (CHINA) CO LTD
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