Plasmon enhancement type Raman spectrum detection chip as well as detection device applying same

Abstract

The invention provides a plasmon enhancement type Raman spectrum detection chip as well as a detection device applying the same. The plasmon enhancement type Raman spectrum detection chip comprises a bearing element and an alloy film, wherein the bearing element is made from a transparent material; the alloy film is formed on one surface of the bearing element; linearly polarized light passing through the bearing element is subjected to total reflection on an interface between the bearing element and the alloy film; an evanescent field generated along with the total reflection penetrates through the alloy film, and excites plasmon on the surface, which is far away from a transparent substrate, of the ally film so as to enhance a Raman spectrum. According to the chip and the detection device, the plasmon enhancement type Raman spectrum detection chip is made from the alloy film which replaces commonly used pure gold films and pure silver films, so that a Raman enhancement factor is higher than that when the pure gold film is adopted and the relatively low cost can be leaded.

Description

technical field [0001] The invention relates to the technical field of molecular spectrum detection, in particular to a plasmon-enhanced Raman spectrum detection chip and a detection device using the same. Background technique [0002] Raman spectroscopy detection technology is mainly used to measure molecular vibration and rotational spectrum, and then obtain information such as material composition, structure and content. Because the Raman scattering cross section of molecules is generally very small, when the concentration of the substance to be detected is low, the Raman signal is extremely weak, and the signal-to-noise ratio is small, so it is difficult to be detected. In order to overcome this shortcoming and lower the detection limit of Raman detection technology, researchers have proposed many methods to enhance Raman signals, including: electronic resonance enhancement, chemical enhancement, localized surface plasmon enhancement, propagating surface plasmon Exciton...

AI Technical Summary

Problems solved by technology

Although pure silver film has the advantage of high Raman enhancement factor, its chemical properties are not stable enough, it is easy to be oxidized and vulcanized, so it is not easy to store and has poor repeatability

Pure gold film has stable chemical properties and is easy to store for a long time, but the cost is high, the adhesion to the glass substrate is poor, and the enhancement factor is lower than that of the silver film, especially the strong force on biomolecules will affect the Raman signal of the molecule itself

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