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Traditional Chinese medicine extract with antitumor activity as well as preparation method and use thereof

A technology of anti-tumor activity and tumor drugs, which is applied in the field of extracts and preparations of Scutellaria chinensis, can solve problems such as unsatisfactory drug treatment effects, achieve good anti-tumor effects, and speed up the research process

Active Publication Date: 2014-02-05
四川梓橦宫药业股份有限公司
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Problems solved by technology

[0003] As one of the important means of treating tumors, drug therapy has achieved certain results, but it is still unsatisfactory for most types of tumors, especially for solid tumors with a high incidence rate. Therefore, discovery and research New and effective anti-tumor drugs are a major topic and long-term task in the field of biomedical research

Method used

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  • Traditional Chinese medicine extract with antitumor activity as well as preparation method and use thereof

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Experimental program
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Effect test

Embodiment

[0022] 1. Extraction of leaves

[0023] Take 1 kg of fresh leaves of Majiazi, add 8-10 times the amount of 95% ethanol to soak for 1-2 days (function: 1, inactivate the active enzyme system in the fresh leaves, and avoid damage to the active ingredients; 2, make the fresh leaves Hardness increases, which is more conducive to the next crushing process), crush the fresh leaves, and then add 10 times the amount of 95% ethanol (60~100% ethanol extraction) and soak for 3 days to extract alcohol-soluble components. Collect the extract, pressurize and recover the ethanol at 30-40°C until there is no alcohol smell, and further freeze-dry the obtained extract concentrate to obtain the alcohol extract of fresh leaves of Semen japonica.

[0024] Dry the extraction residue, add 8 to 10 times the amount of water and soak for 3 days to extract the water-soluble components, collect the extract, and freeze-dry to obtain the water extract of the fresh leaves of Saccharomyces japonicus.

[002...

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Abstract

The invention discloses a traditional Chinese medicine extract with an antitumor activity. The traditional Chinese medicine extract is extracted from paliurus ramosissimus leaves. The invention also discloses a method for preparing the traditional Chinese medicine extract by alcohol extraction with an ethanol solution, and use of the traditional Chinese medicine extract in preparing a medicament for treating tumors. The traditional Chinese medicine extract has good inhibition effects on tumors.

Description

technical field [0001] The invention relates to the field of extraction and application of traditional Chinese medicines, in particular to an extract of vegetal vetch with anti-tumor activity and its preparation method and application. Background technique [0002] Tumor is a common and frequently-occurring disease that endangers human health most seriously. Traditional Chinese medicine treatment of tumors has a unique effect in stabilizing tumors, regulating body functions, increasing immunity, improving clinical symptoms, reducing toxic and side effects of radiotherapy and chemotherapy, and prolonging survival time with tumors. At present, traditional Chinese medicine in the motherland has made remarkable achievements in the treatment of tumors. It is a very meaningful exploration to vigorously carry out research on the treatment of tumors with traditional Chinese medicine. Plants are not only one of the important sources of new antineoplastic drugs, such as the discovery...

Claims

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Application Information

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IPC IPC(8): A61K36/72A61P35/00A61K127/00
Inventor 徐超群袁志翔阮佳李东晓詹雁谭镭
Owner 四川梓橦宫药业股份有限公司
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