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Preparation of Feining Concentrated Pills

The technology of a concentrated pill and a pill making machine is applied in the field of preparation of Feining concentrated pills, which can solve the problems of low content of active ingredients, long disintegration time, large dosage and the like, and achieves fast dissolution speed, small dosage and high content. Effect

Inactive Publication Date: 2016-03-23
LIAONING PENGJIAN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, there are granules, capsules, tablets, and water pills in the preparations of Hunhuncao. Compared with concentrated pills, these dosage forms have the disadvantages of large dosage, inconvenient taking, long disintegration time, slow dissolution, low content of active ingredients, and slow onset of action.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] The present invention discloses the preparation of Feining concentrated pills. The preparation of the Feining concentrated pills includes the following steps:

[0020] A. Select 200Kg of Revenant Grass as a raw material, and add the Revenant Grass raw material into a 3T ultrasonic extraction tank;

[0021] B. Add 2000Kg of water to the ultrasonic extraction tank, and soak the raw material of Resurrection Herb for 2 hours;

[0022] C. Extract at an ultrasonic frequency of 60KHz and a temperature of 45°C, and extract three times, wherein the first extraction time is 1 hour, and the second and third extractions are 0.5 hours;

[0023] D. Combine the extracts, decoct, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.23 to 1.28 (at 60°C) to obtain the extract. Place the extract at 75°C and dry until the water content is 6%. After that, the extract After the paste is pulverized, pass through a 100-mesh sieve to obtain the herba extract p...

Embodiment 2

[0028] A. Select 180Kg of Revenant Grass as a raw material, and add the Revenant Grass raw material into a 3T ultrasonic extraction tank;

[0029] B. Add 2000Kg of water to the ultrasonic extraction tank, and soak the raw material of Resurrection Herb for 8 hours;

[0030] C. Extract at an ultrasonic frequency of 120KHz and a temperature of 75°C, and extract three times, wherein the first extraction time is 2 hours, and the second and third extractions are 1 hour;

[0031] D. Combine the extracts, decoct, filter, and concentrate the filtrate under reduced pressure to 1.23-1.28 (at 60°C) to obtain the extract. Place the extract at 85°C to dry until the moisture is 2%, and then crush the extract After passing through a 100-mesh sieve, the Herba Herba extract powder is obtained;

[0032] E, form mixed powder after mixing 1Kg Herba Herba Extract powder with 0.5Kg starch, 0.5Kg microcrystalline cellulose, 0.5Kg carboxymethyl starch sodium;

[0033] F, the production of concentrat...

Embodiment 3

[0036] A. Select 200Kg of Revenant Grass as a raw material, and add the Revenant Grass raw material into a 3T ultrasonic extraction tank;

[0037] B. Add 2800Kg of water to the ultrasonic extraction tank, and soak the raw material of Herb Resurrection for 4 hours;

[0038] C. Extract at an ultrasonic frequency of 80KHz and a temperature of 55°C, and extract three times, wherein the first extraction time is 1.5 hours, and the second and third extractions are 0.7 hours;

[0039] D. Combine the extracts, decoct, filter, and concentrate the filtrate under reduced pressure to a relative density of 1.23 to 1.28 (at 60°C) to obtain the extract. Place the extract at 80°C to dry until the moisture is 4%, and then extract After the paste is pulverized, pass through a 100-mesh sieve to obtain the herba extract powder;

[0040] E, form mixed powder after mixing 20Kg Herba Herba Extract powder with 10Kg starch, 1.5Kg microcrystalline cellulose, 1.3Kg sodium carboxymethyl starch;

[0041]...

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Abstract

The invention discloses a preparation method of a lung-soothing concentration pill. The preparation method comprises the following steps: taking hempleaf groundsel herb as raw materials, adding water to soak the hempleaf groundsel herb, performing extraction through an ultrasonic extraction tank, and merging the extracts for decoction, filtering and concentration to obtain an extractum; drying and crushing extractum to sieve by a 100-mesh sieve, so as to obtain hempleaf groundsel herb extractum powder; mixing with starch, microcrystalline cellulose and sodium carboxymethyl starch to form mixture powder; preparing the concentration pill by a centrifugal coating palletizing machine. The concentration pill has the benefits of reducing fever, eliminating phlegm, relieving cough and relieving asthma, can be used for lungs infection, chronic bronchitis, asthmatoid bronchitis, acute respiratory tract infection and the like. According to the invention, as ultrasonic extraction is adopted, the dissolving-out amount of effective component of materials to be extracted can be improved in unit time, and the prepared concentration pill is high in effective component content, small in taking dose and small in local irritation.

Description

【Technical field】 [0001] The invention relates to a preparation method of Feining concentrated pills, in particular to a preparation method of Feining concentrated pills with the functions of clearing away heat and eliminating phlegm, antitussive and calming kicks. 【Background technique】 [0002] Cough and asthma is a common respiratory disease that seriously endangers human health. It is caused by external adverse stimuli or visceral malnutrition, resulting in damage to the lungs, spleen and kidneys, resulting in inflammation, causing increased thick secretions. With repeated attacks, thick secretions The secretion can form a sputum plug. [0003] Senciocannabifolius Less is the aerial part of Senciocannabifolius Less, and its main active ingredients include caffeic acid and chlorogenic acid. Studies have shown that Hunhuncao has the effects of clearing away heat and eliminating phlegm, relieving cough and relieving asthma. For pulmonary infection, chronic bronchitis, ast...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/28A61K36/28A61P11/14A61P11/06A61P11/10A61P11/00
Inventor 陈越主萍张丹夏桂云欧雪梅梁跃裴颖吴佳杜艳
Owner LIAONING PENGJIAN PHARMA CO LTD
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