Preparation method of polyurethane bandage with functions of sterilization and itch relief and bandage manufactured by method
A sterilization and antipruritic, polyurethane technology, applied in the field of medical and sanitary products, can solve the problems of expensive raw materials of polyurethane bandages, insufficient breathability of the bandages, redness and itching of the skin, etc., and achieves the effects of low manufacturing cost, prevention of redness, swelling and itching, and light weight.
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Embodiment 1
[0036] ① Preparation of polyurethane prepolymer
[0037] Add 100 parts of 4,4'-diphenylmethane diisocyanate, 0.5 parts of benzoyl chloride stabilizer and 2.5 parts of silicone defoamer After stirring at 45°C for 30 minutes, slowly add 20 parts of polypropylene glycol with a molecular weight of 800-1100, continue heating and stirring for 60 minutes, then add 35 parts of polypropylene glycol with a molecular weight of 1800-2200 dropwise, and add the catalyst dimethylethanolamine after 2 hours of reaction 3 parts, lubricant silicone oil 5 parts, continue heating and stirring for 15 minutes to obtain polyurethane prepolymer.
[0038] ②Preparation of chitosan microspheres with bactericidal and antipruritic drugs
[0039] Dissolve 50 parts of chitosan in 5% acetic acid solution with a mass fraction of 5%, stir until completely dissolved, centrifuge and coagulate to obtain the chitosan solution; after standing for 36 hours, filter under reduced pressure, wash with absolute ethanol u...
Embodiment 2
[0043] ① Preparation of polyurethane prepolymer
[0044] In a four-port reactor with a stirrer and a thermometer that feeds high-purity nitrogen, add 100 parts of 2,4'-diphenylmethane diisocyanate, 1.8 parts of benzoyl chloride and 3.2 parts of silicone defoamer. After stirring at 30°C for 30 minutes, slowly add 18 parts of polytetrahydrofuran diol with a molecular weight of 800-1100, continue heating and stirring for 90 minutes, then add 40 parts of polypropylene glycol with a molecular weight of 1800-2200 dropwise, and add the catalyst triethylene glycol after 2.5 hours of reaction. 1-8 parts of diamine, 3-10 parts of silicone oil lubricant, and continue heating and stirring for 50 minutes to obtain a polyurethane prepolymer.
[0045] ②Preparation of chitosan quaternary ammonium salt with bactericidal and antipruritic functions
[0046] In 10 parts of acetone medium, add 5 parts of mass fraction of 30% sodium hydroxide as an acid-binding agent, add 5 parts of quaternizing a...
Embodiment 3
[0050] ① Preparation of polyurethane prepolymer
[0051] In a four-port reactor with a stirrer and a thermometer that is fed with high-purity nitrogen, add 100 parts of 4,4'-diphenylmethane diisocyanate, 4.2 parts of propionyl chloride and 3.5 parts of silicone defoamer. After stirring at ℃ for 30 minutes, slowly add 30 parts of polyether triol with a molecular weight of 300-600, continue heating and stirring for 70 minutes, then add 10 parts of polytetrahydrofuran diol with a molecular weight of 1800-2200 dropwise, react for 1.5 hours, and then add an organotin catalyst 3 parts of dibutyltin dilaurate and 5 parts of silicone oil lubricant in the mixture, and continue heating and stirring for 45 minutes to obtain a polyurethane prepolymer.
[0052] ②Preparation of chitosan microspheres with bactericidal and antipruritic drugs
[0053] Dissolve 50 parts of chitosan in 15% acetic acid solution, stir until completely dissolved, obtain chitosan solution, and centrifuge to coagula...
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