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Pharmaceutical composition for treating postpartum perineal mucosal lesions

A composition and mucosal technology, applied in the directions of drug combinations, sexual diseases, pharmaceutical formulations, etc., can solve problems such as unfavorable long-term prognosis, irritation of mucosa, mucosal irritation, etc., to reduce the type and dosage of drugs, increase local stimulation, and promote absorption. Effect

Inactive Publication Date: 2013-09-18
朱月英
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But in fact, the basic pathology of the disease is as follows: postpartum estrogen levels drop rapidly, causing relatively atrophy of the vaginal wall, thinning of the mucous membrane, reduction of glycogen content in epithelial cells, increase of Ph value in the vagina, decrease of local resistance, pathogenic bacteria Easy to invade and reproduce and cause inflammation
The magnesium sulfate and potassium permanganate flushing solution is also a kind of stimulation to the mucous membrane, which can solve the problem of early mucous membrane edema, but it is not good for the long-term prognosis.
[0004] There are many perineal wet compresses in traditional Chinese medicine, but most of them are aimed at women of childbearing age. The prescriptions often contain dehumidification drugs such as Sophora flavescens, Cnidium chinensis, Kochia chinensis, and Smilax smilax. Thinning caused by external application of the above bitter cold and dampness medicines will irritate the mucous membranes and lead to aggravation of the disease
And the bitter cold of the above-mentioned drugs is not conducive to postpartum recovery

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Example 1, the weight ratio of raw materials: Pittogonia bark 20g, triangle grass 10g, bobbin 6g, mountain ginger 10g, mulberry 6g, cat's claw grass 10g, burnt malt 10g, burnt Shenqu 10g, ephedra root 10g, saponins Thorn 2g, peach gum 6g, calamus 20g.

[0031] The preparation method of Example 1 is: mix Pittogonia bark, trigonum chinensis, bobbin, mountain ginger, mulberry, cat's claw, burnt malt, burnt Shenqu, ephedra root, saponin thorn, peach gum, and iris calamus, and add water Decoct, take the filtrate after 30 minutes, add water to the dregs of the medicine and continue to decoct for 20 minutes, then take the filtrate, combine the two times of filtrate for wet compress, once a day.

Embodiment 2

[0032] Example 2, the weight ratio of raw materials: 10 parts of Pittogonia bark, 6 parts of triangular grass, 3 parts of bobbin, 6 parts of mountain ginger, 3 parts of mulberry, 6 parts of cat's claw, 6 parts of Jiaomaiya, 6 parts of Jiao Shenqu 3 parts, 6 parts of ephedra root, 1 part of saponins, 3 parts of peach gum, and 10 parts of calamus calamus.

Embodiment 3

[0033] Example 3, the weight ratio of raw materials: 20 parts of Pittogonia bark, 10 parts of triangular grass, 6 parts of bobbin, 10 parts of mountain ginger, 6 parts of mulberry, 10 parts of cat's claw grass, 10 parts of burnt malt, 10 parts of Jiao Shenqu 10 parts, 10 parts of ephedra root, 2 parts of saponins, 6 parts of peach gum, 20 parts of iris calamus.

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating postpartum perineal mucosal lesions, so as to solve the problem of treatment of postpartum perineal mucosal lesions. The pharmaceutical composition is characterized by being prepared from the following crude drugs: bark of himalayan coralbean, smallflower bracketplant herb, bobbin, alpinia japonica, parasitic loranthus, radix ranunculi ternate, dark malt, burnt medicated leaven, Chinese ephedra root, spina gleditsiae, peach gum, and rhizome anemones altaicae. The clinical test shows that the pharmaceutical composition has the characteristics of good curative effect and high safety on treatment of the postpartum perineal mucosal lesions, and is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a pharmaceutical composition for treating postpartum perineal mucosal lesions. Background technique [0002] The postpartum uterus, cervix, vagina, and perineum will undergo a series of changes due to the rapid decline in hormone levels. For the perineum, during childbirth, the fetus squeezes the outer opening of the vagina. It often causes perineal congestion, edema, or varying degrees of laceration, which gradually disappear within 7 days thereafter. At the same time, due to the reduction of the surrounding folds in the perineum, the mucous membrane in the vagina is flat, and the defense of the mucous membrane is reduced, which is easy to cause symptoms such as vulvar itching and vaginal dryness. Generally speaking, in a short period of time, the vaginal mucosa is not easy to fully recover to the situation before pregnancy. Only after the cessation of breastfeeding...

Claims

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Application Information

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IPC IPC(8): A61K36/9062A61P15/00
Inventor 丁霄雁冯涛耿慧
Owner 朱月英
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