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Postoperative drug for chronic peptic ulcer and esophagitis syndrome

A technology for peptic ulcer and esophagitis, which is applied in the field of postoperative medication for chronic peptic ulcer and esophagitis syndrome, can solve the problems that the pathological process cannot be terminated, the clinical effect is not obvious, and the recurrence rate is reduced, so as to reduce the types of drugs and Dosage, increase the burden on the liver and kidney, and increase the effect of curative effect

Inactive Publication Date: 2015-03-11
QINGDAO CENT HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the clinical effect is not obvious
Most of them ultimately rely on surgical treatment, but after surgical treatment, the pathological process of gastric columnar esophageal transition cannot be terminated in some cases, resulting in a relatively high recurrence rate
Therefore, there is currently a lack of a drug for improving the abnormal proliferation of mucosal cells and reducing the recurrence rate after endoscopic treatment of chronic peptic ulcer and esophagitis syndrome, as well as after surgical treatment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Example 1, the weight ratio of raw materials: litchi core 20g, upland grass 10g, water safflower 6g, platycodon 10g, genus 6g, terrazzo vine 10g, kudzu root 10g, aescin 10g, loofah 12g, pangolin 2g, burnt malt 6g, burnt grain sprouts 20g.

[0030] The preparation method of Example 1 is: mix lychee core, dry field grass, water safflower seeds, platycodon grandiflorum, genus stalks, terrazzo vine, kudzu root, aescin, luffa, pangolin, burnt malt, burnt grain buds, add water and decoct, Take the filtrate after 30 minutes, add water to the dregs of the medicine and continue to decoct for 20 minutes, then take the filtrate, combine the two filtrates, divide into two parts and take it in the morning and evening.

Embodiment 2

[0031] Example 2, the weight ratio of raw materials: 10 parts of litchi core, 6 parts of upland grass, 3 parts of water safflower, 6 parts of Platycodon grandiflorum, 3 parts of stalk grass, 6 parts of terrazzo, 6 parts of kudzu root, and Aescin 6 parts, 6 parts of loofah, 1 part of pangolin, 3 parts of burnt malt, 10 parts of burnt grain sprouts.

Embodiment 3

[0032] Example 3, the weight ratio of raw materials: 20 parts of lychee core, 10 parts of upland grass, 6 parts of water safflower, 10 parts of platycodon grandiflorum, 6 parts of stalk grass, 10 parts of genus vine, 10 parts of kudzu root, and aescin 10 parts, loofah 10 parts, pangolin 2 parts, burnt malt 6 parts, burnt grain sprouts 20 parts.

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PUM

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Abstract

The invention discloses a postoperative drug for chronic peptic ulcer and esophagitis syndrome. The drug is applied to the postoperative treatment of chronic peptic ulcer and esophagitis syndrome. The drug is characterized by being prepared from the following raw pharmaceutical materials in proportioning ratio by weight: litchi chinensis Sonn., lindernia ruellioides (Colsm.)Pennell, polygonum orientale L., radix platycodi, aeschynomene indica L., trachelospermum jasminoides (Lindl.) Lem., radix puerariae, paris polyphylla Sm., luffa cylindrica (L.) Roem., manis pentadactyla Linnaeus, hordeum vulgare L. and setaria italica (L.) Beauv.. Proved by clinical trials, the drug has the characteristics of low recurrence rate and high safety in the postoperative treatment of chronic peptic ulcer and esophagitis syndrome, so that the method is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to postoperative medication for chronic peptic ulcer and esophagitis syndrome. Background technique [0002] Chronic peptic ulcer and esophagitis syndrome refers to the replacement of the lower esophageal mucosa by the gastric columnar epithelium. Intrinsic can be congenital, but often secondary to reflux esophagitis, esophagitis and ulcers occur on the basis of gastroesophageal reflux. The pathological feature is that the acid-resistant squamous epithelium is damaged, and the acid-resistant columnar epithelium regenerates and gradually spreads upwards to involve the lower esophagus. Ulcers can penetrate the wall of the esophagus, causing mediastinal tissue fibrosis and lymphadenitis. If blood vessels are damaged, they can cause bleeding, and there may be purulent lesions in the mediastinum and pleura. Microscopic examination of the mucosal lining shows abnormalities an...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8998A61K9/48A61P1/00A61P1/04A61K35/36
Inventor 张淑玲纪雪梅于德洋李莉
Owner QINGDAO CENT HOSPITAL
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