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A preparation method of medicine for treating Barrett's syndrome

A syndrome and Barrett technology, applied in the field of drug preparation, to achieve the effects of being easy to carry, easy to take, and preventing regeneration and migration

Inactive Publication Date: 2015-09-30
毛从俊 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Traditional Chinese medicine also often confuses the two treatments, and starts with liver qi invading the stomach, stagnant heat in the liver and stomach, and spleen and stomach yin deficiency. The treatment can improve gastrointestinal motility and solve symptoms such as epigastric pain and belching, but it cannot fundamentally solve the "columnar stomach" Epithelial esophagus transition" is a pathological factor, so once eating cold or hot food, especially acidic food, it will relapse
Therefore, at present, patients with Barrett's syndrome often undergo surgery due to frequent attacks, and surgical resection of the transitional part of the gastric columnar epithelium and esophagus is performed.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Example 1, the weight ratio of raw materials: 10 parts of litchi core, 6 parts of holy basil, 3 parts of poria cocos, 6 parts of tangerine peel, 3 parts of stalked grass, 6 parts of terrazzo, 6 parts of kudzu root, 6 parts of aescin, 6 parts of loofah, 1 part of provincial bird flower, 3 parts of burnt malt, 10 parts of burnt grain bud.

Embodiment 2

[0035] Embodiment 2, raw material drug weight ratio: 20 parts of litchi cores, 10 parts of holy basil, 6 parts of Poria cocos, 10 parts of dried tangerine peel, 6 parts of stalks, 10 parts of terrazzo, 10 parts of kudzu root, 10 parts of Aescin, 10 parts of loofah, 2 parts of provincial bird flower, 6 parts of burnt malt, 20 parts of burnt grain bud.

Embodiment 3

[0036] Embodiment 3, raw material drug weight ratio: 30 parts of litchi cores, 12 parts of holy basil, 10 parts of poria cocos, 12 parts of dried tangerine peel, 10 parts of stalks, 12 parts of terrazzo, 12 parts of kudzu root, 12 parts of aescin, 12 parts of loofah, 5 parts of provincial bird flower, 10 parts of burnt malt, 25 parts of burnt grain bud.

[0037]The Chinese medicine of embodiment 1~3 can be prepared by the following method:

[0038] (1) Extract the volatile oils from Pueraria lobata, holy basil, and cassia basil powder by steam distillation, and collect them and mix them for later use;

[0039] (2) Grind burnt grain buds and burnt malt through a 150-mesh sieve to form fine powder for later use;

[0040] (3) Mix lychee core, Poria cocos, tangerine peel, scorpion vine, loofah, aescin, and parsley, add 10 times the amount of water, add water to decoct twice, each time for 1 hour, combine the decoction, and let it stand; Then add 3 to 4 times of 95% ethanol to th...

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PUM

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Abstract

The invention discloses a medicament for treating balintss syndrome so as to solve the problem of treating balintss syndrome. The medicament is characterized by being prepared from the following raw materials: lichee seeds, ocimum tenuiflorum, poria cocos, dried orange peel, aeschynomene indica, trachelospermum jasminoides, radix puerariae, paris polyphylla, vegetable sponge of luffa, common exbucklandia stem, coking malt and coking millet sprouts. The preparation method of the medicament comprises: (1) extracting volatile oil from coarse powder of radix puerariae, ocimum tenuiflorum and aeschynomene indica for reservation; (2) crushing coking millet sprouts into fine powder for reservation; (3) performing water extraction and alcohol precipitation on lichee seeds, poria cocos, dried orange peel, trachelospermum jasminoides, vegetable sponge of luffa, paris polyphylla, common exbucklandia stem, coking malt and coking millet sprouts, drying to obtain primary materials; and (4) spraying the volatile oil into the primary materials, mixing uniformly with coking millet sprouts, sieving by a sieve of 60 meshes and performing tabletting. Clinical experiments confirm that the medicament for treating balintss syndrome has the characteristics of good treatment effect and relatively high safety, and is worth clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a preparation method of a medicine for treating Barrett's syndrome. Background technique [0002] Barrett's syndrome (Barrett's syndrome), also known as Barrett's ulcer, refers to the replacement of the lower esophageal mucosa by the gastric columnar epithelium. It was first described by Barrett in 1950, so it is called Barrett syndrome. Intrinsic can be congenital, but often secondary to reflux esophagitis, esophagitis and ulcers occur on the basis of gastroesophageal reflux. The pathological feature is that the acid-resistant squamous epithelium is damaged, and the acid-resistant columnar epithelium regenerates and gradually spreads upwards to involve the lower esophagus. Ulcers can penetrate the wall of the esophagus, causing mediastinal tissue fibrosis and lymphadenitis. If blood vessels are damaged, they can cause bleeding, and there may be purulent lesions in ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8998A61K9/20A61P1/04
Inventor 毛从俊杨修方邢金山
Owner 毛从俊
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