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Application of elaeagnus conferta roxb

A technology of goat milk fruit and application, applied in the field of traditional Chinese medicine, can solve the problems of liver damage to the nervous system, many adverse reactions, skin allergies, etc.

Inactive Publication Date: 2013-06-26
盛艳
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these drugs have many adverse reactions. Benzbromarone can cause severe liver damage and adverse reactions to the nervous system. Allopurinol can cause skin allergies, liver damage, and hypersensitivity allergic syndrome, which can be life-threatening in severe cases.

Method used

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  • Application of elaeagnus conferta roxb

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Goat's Milk Fruit for Kidney Stones

[0031] experimental method:

[0032] Get 50 Wistar rats (male, body weight 180-220g, SPF grade, China Pharmaceutical and Biological Products Identification Institute provides), be divided into five groups at random, namely control group, model group, positive control group, high-dose group, low-dose group . Rats in each group were fed with normal diet and distilled water. Rats in the model group, the positive control group, the high-dose group, and the low-dose group were given 2 mL / rat by intragastric administration of 1% ethylene glycol (EG)+2% ammonium chloride (AC) every day. Drugs were administered at the beginning of modeling, once a day for 8 consecutive weeks. As the positive control group, the traditional Chinese medicine Shenshitong Granules was selected as the positive control drug, and 3g / kg was intragastrically administered every day. After the goat milk fruit is crushed, a suspension is prepared with 0.5% sodium ca...

Embodiment 2

[0071] Preparation of Goat's Milk Fruit Water Extract

[0072] Goat milk fruit is selected and cleaned, 2500g is taken, crushed on a masher, added with 10L of water, decocted and extracted for 30 minutes, filtered, and the filtrate is concentrated to 500mL to obtain the goat milk fruit aqueous extract.

[0073] Goat's milk fruit water extract in the treatment of kidney stones

[0074] experimental method:

[0075] Get 50 Wistar rats (male, body weight 180-220g, SPF grade, China Pharmaceutical and Biological Products Identification Institute provides), be divided into five groups at random, namely control group, model group, positive control group, high-dose group, low-dose group . Rats in each group were fed with normal diet and distilled water. Rats in the model group, the positive control group, the high-dose group, and the low-dose group were given 2 mL / rat by intragastric administration of 1% ethylene glycol (EG)+2% ammonium chloride (AC) every day. Drugs were administ...

Embodiment 3

[0114] Preparation of Dehydrated Goat's Milk Fruit

[0115] The goat milk fruit is selected, cleaned, and the peel is needled, and dehydrated with a sugar-salt mixture at normal temperature and pressure for 24 hours. After the water is filtered, it is dried by hot air convection at 65°C for 3-5 hours, and the dehydrated goat is obtained after ventilation and cooling. milk fruit.

[0116] Dehydrated Goat's Milk Fruit for Kidney Stones

[0117] experimental method:

[0118] Get 50 Wistar rats (male, body weight 180-220g, SPF grade, China Pharmaceutical and Biological Products Identification Institute provides), be divided into five groups at random, namely control group, model group, positive control group, high-dose group, low-dose group . Rats in each group were fed with normal diet and distilled water. Rats in the model group, the positive control group, the high-dose group, and the low-dose group were given 2 mL / rat by intragastric administration of 1% ethylene glycol (E...

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Abstract

The invention discloses an application of elaeagnus conferta roxb, namely the application of the elaeagnus conferta roxb in preparation of drugs for treating kidney stones, gall-stone and hyperuricemia. In the treatment of the kidney stones, the drug is used for reducing the rate of the kidney stones, improving kidney coefficient, reducing calcium content of the kidney, reducing serum urea nitrogen and reducing serum creatinine. In the treatment of the gall-stone, the elaeagnus conferta roxb is used for treating bile pigment gallstones and cholesterol gallstones; preferably in the treatment of bilirubin gallstones, the elaeagnus conferta roxb is used for reducing the rate of the gallbladder stones, calcium ion content in bile, total bilirubin concentration and free bilirubin concentration in the treatment of the bile pigment gallstones; in the treatment of the cholesterol gallstones, the elaeagnus conferta roxb is used for reducing the rate of the gallbladder stones and the cholesterol content in the bile; and in the treatment of hyperuricemia, the elaeagnus conferta roxb is used for reducing uric acid content in serum. The application of the elaeagnus conferta roxb can be spread to related products of the elaeagnus conferta roxb; and the related product includes a fruit aqueous extract of the elaeagnus conferta roxb, dewatered elaeagnus conferta roxb, capsules, troches, granulas, fruit vinegar, jam and fruit juice.

Description

technical field [0001] The present invention relates to the use of a kind of goat's milk fruit. Specifically, the invention relates to the use of a kind of goat's milk fruit in the preparation of medicines for treating kidney stones, gallstones and hyperuricemia, and belongs to the field of traditional Chinese medicine. Background technique [0002] Goat milk fruit (Elaeagnus conferta Roxb), also known as dense flower conferta Roxb, southern conferta Roxb, large fruit conferta, vine conferta, marang fruit, maluan fruit, is a wild medicinal and edible plant , widely distributed in the tropical rain forests of Vietnam, Malaysia, India and other places, as well as southern Yunnan and southern Guangxi of my country. It is very rich in nutrients. According to reports, every 100g of fresh fruit contains 12-30 mg of vitamin C, 3.15 mg of carotene, and 0.4-0.7 mg of vitamin B; the pulp contains 5.11% sugar, 1.45% total acid, 2.46% crude protein, and 2.88% crude fat; The content of ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P13/04A61P1/16A61P19/06A23L2/38A23L2/02A23L1/06A61K131/00A23L21/10
Inventor 盛艳
Owner 盛艳
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