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Device for preventing and treating posterior capsule opacification

A cataract, post-occurrence technology, applied in ophthalmic surgery and other directions, can solve problems such as overflow into aqueous humor or other tissues, reduce the incidence of post-occurrence cataract, cannot avoid post-occurrence cataract, etc., achieve less complications, Good practical value, avoid the effect of other cells and important structures

Inactive Publication Date: 2013-05-15
BEIJING TONGREN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, improvements have been made in the design of intraocular lenses to reduce the incidence of post-cataract, mainly including: (1) improving the biocompatibility of intraocular lens materials and reducing the fibrosis of the posterior capsule; The edge design prevents LEC from migrating to the visual axis, but it still cannot avoid the occurrence of posterior cataract
[0007] Among these methods, there is a kind of method that perfuses trypsin solution into the lens capsule through various instruments to kill the lens epithelial cells on the inner surface of the lens capsule. However, the disadvantage of this method is that the trypsin solution may damage the lens in advance. The hole formed by capsulorhexis overflows into the aqueous humor or other tissues, thereby damaging other tissues in the eye

Method used

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  • Device for preventing and treating posterior capsule opacification
  • Device for preventing and treating posterior capsule opacification
  • Device for preventing and treating posterior capsule opacification

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0036] Preparation Example

[0037] Trypsin (Sigma Company); silica gel (Qingdao Ocean Chemical Factory); glutaraldehyde (Chengdu Huaxi Biochemical Products Factory); BSA (bovine serum albumin, Sigma Company); PBS (phosphate buffer solution, pH7.0) was Prepared by the laboratory itself.

[0038] (1) Take a beaker, wash it with Wujie powder and double-distilled water, add double-distilled water, put the silicone elastic film into it and ultrasonically clean it for 5min*3, pay attention to the fact that all the silicone must sink to the bottom of the water.

[0039] (2) Take PBS (phosphate buffer solution) with pH 7, and adjust the pH value to 7.4 by adding KOH. Take 50mg of trypsin + 1ml of the above PBS (pH7.4) to make a 50mg / ml enzyme solution.

[0040] (3) Take 10mg BSA + 990μl double distilled water to prepare 1% BSA solution.

[0041] (4) Take 20 μl 50% glutaraldehyde solution + 980 μl double distilled water to prepare 1% glutaraldehyde solution.

[0042](5) Cross-link...

Embodiment 1

[0046] refer to figure 1 and figure 2 , The device for preventing and treating post-cataract of the present invention consists of a container 1, a piston 6, a heat insulating tube 2 and an elastic membrane 3, the piston 6 is arranged in the container 1, and the container 1 has an outlet port 11. Wherein, both ends of the heat insulating pipe 2 are open, one end of the heat insulating pipe 2 is connected to the outlet port 11, the elastic film 3 is arranged on the heat insulating pipe 2 and closes the other end of the heat insulating pipe 2, and the material of the elastic film 3 is rubber , The piston 6 and the container 1 form a closed device 7 with an adjustable volume, and the closed device 7 shown in this embodiment constitutes the structure of a syringe. Pressing down on the piston 6 reduces the volume of the volume-adjustable closure device 7, and the elastic film 3 expands from the other end of the heat-insulating tube 2 in an ellipsoidal shape to form a blister 31, t...

Embodiment 2

[0049] refer to Figure 5 to Figure 8 , The device for preventing and treating post-cataract of the present invention is made up of container 1, piston 6, heat insulation tube 2 and test tube-shaped elastic film 4, and piston 6 is arranged in container 1, and container 1 has outlet port 11. Wherein, both ends of the heat insulating tube 2 are open, and one end is connected to the outlet port 11. The test tube-shaped elastic membrane 4 is located in the heat insulating tube 2, and the piston 6 and the container 1 form a closed device 7 with an adjustable volume. The test tube-shaped elastic membrane 4 The material is rubber, and one end of the test tube-shaped elastic membrane 4 is a closed blind end, and the other end has an open end. The open end of the test tube-shaped elastic membrane 4 communicates with the outlet end 11 of the container 1 , and the blind end is located in the heat insulating tube 2 . Pressing down on the piston 6 reduces the volume of the closed containe...

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Abstract

The invention provides a device for preventing and treating posterior capsule opacification. The device for preventing and treating the posterior capsule opacification comprises a container, a heat insulation pipe and an elastic membrane. An outlet end is arranged on the container. A piston which is used for squeezing out contents in the container from the output end is arranged inside the container. Two ends of the heat insulation pipe are open, wherein one end is connected with the output end of the container. The heat insulation pipe is outside sealed, the elastic membrane is arranged at the other end of the heat insulation pipe, or the elastic membrane is a test-tube-shaped elastic membrane which is arranged inside the heat insulation pipe. The test-tube-shaped elastic membrane bulges out of the heat insulation pipe to form a bubble under the action of the piston, wherein trypsin is fixed on the outer surface of the bubble which is formed by the elastic membrane. The device for preventing and treating the posterior capsule opacification can selectively remove crystalline lens epithelial cells in extracapsular cataract extraction, and therefore occurring of posterior capsular opacification is avoided.

Description

technical field [0001] The present invention relates to a device, and more particularly, to a device for prevention and treatment of posterior cataract, which is capable of selectively removing lens epithelial cells to prevent posterior capsule opacity during extracapsular cataract extraction surgery of happening. Background technique [0002] Cataract removal surgery is one of the most common operations in ophthalmology. The cataract lens is located in a lens capsule. To access the cataract lens, an incision is made in the edge of the eye to allow a surgical instrument to be inserted into the anterior chamber of the eye. In extracapsular cataract extraction, a capsulorhexis procedure is performed, that is, a surgical cutting instrument is used to create a hole in the anterior lens capsule to allow direct access from the anterior chamber to the cataract lens. Next, the cataract lens is removed by various existing methods, for example, phacoemulsification and the like. In ...

Claims

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Application Information

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IPC IPC(8): A61F9/007
Inventor 赵阳朱思泉李霄
Owner BEIJING TONGREN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV
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