Full-sealing process for preparing azamethiphos cleanly

Abstract

The invention provides a full-sealing process for preparing azamethiphos cleanly. The process comprises the following steps: providing a reaction device; preparing a branch-chain chloro-product: introducing chlorine gas into a rotational flow kettle, which comprises a first body, wherein the first body is arranged in a hollow manner, so that a first reaction cavity with an inverted cone structure is formed; mixing raw materials such as oxazole [4,5-b] pyridine-2(3H) ketone, N, N-dimethylformamide, paraformaldehyde, sulfoxide chloride and the like, and injecting into the rotational flow kettle, so that the raw materials have a reaction in the first reaction cavity and the branch-chain chloro-product is obtained; preparing phosphorothioate in a second reaction unit; and preparing azamethiphos in a third reaction unit. According to the full-sealing process for preparing azamethiphos cleanly, azamethiphos can be prepared cleanly under a full-sealing environment.

Description

technical field [0001] The invention relates to a production process of picoline, in particular to a process for fully sealed and clean preparation of picoline. Background technique [0002] Pyridophos-methyl, also known as pyridophos-methyl, is an excellent insecticide, and its chemical name is S-[6-chloro-oxazole(4,5-b)pyridin-2(3hydrogen)-one group -Methyl]-O,O-dimethyl phosphorothioate with the formula C 9 h 10 ClN 2 o 5 PS, the molecular weight is 324.68. Pyridophos is an excellent acaricide with insecticidal activity. It is a contact and stomach poison with good long-lasting effect and wide insecticidal spectrum. It can be used in cotton, fruit trees, vegetables and livestock, public health and family , prevent and control various mites and moths, aphids, leaf lice, small borers, potato beetles, flies, cockroaches, etc. This agent has low toxicity to humans and animals, and is a safe agent with high efficiency, low toxicity, and low residue. Therefore, picophos B...

AI Technical Summary

Problems solved by technology

[0005] However, when the branched-chain chlorinated product is prepared by the traditional process, it is difficult to achieve complete sealing, and the first reaction unit 100 is prone to running, popping, dripping, and leaking during the preparation process.

The gas (such as hydrogen chloride) produced by the branched chlorinated product in the preparation process is highly toxic and corrosive, and leakage will easily affect the production environment and human health, which is not conducive to environmental protection.

There are two reasons: the first, because the oxazol[4,5-b]pyridin-2(3H) ketone is a solid raw material, it needs manual feeding every time, and the first reaction must be opened for manual feeding. kettle 10, affecting the sealing of the first reaction kettle 10

Second, since the first reactor 10 has a first stirring device 50, the sealing point between the first stirring device 50 and the first reactor 10 is easily affected by the raw materials for preparing the branched chlorinated products such as chlorination. The corrosion of sulfoxide and the gas produced in the reaction, such as hydrogen chloride, affects the sealing of the first reaction kettle 10 and becomes a hidden danger that cannot prevent the leakage of harmful gases

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