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Chinese medicine for treating women dysmenorrhea and preparation method of external patch of Chinese medicine

A technology for women and traditional Chinese medicine, applied in the field of medicine, can solve the problems of treating the symptoms but not the root cause, reducing drug sensitivity, weakening the curative effect, etc., and achieving the effects of high absorption efficiency, large drug loading, and improved therapeutic effect.

Active Publication Date: 2013-04-24
XIAN MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a traditional Chinese medicine for treating female dysmenorrhea, which solves the problem that the existing chemical pharmaceutical preparations treat the symptoms but not the root cause, and long-term medication tends to reduce the sensitivity of patients to the medicine and weaken the curative effect.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Step 1: Weigh 800g of Artemisia argyi leaves, 1,500g of fenugreek, 600g of dogwood, 900g of cassia twig, 600g of Rhizoma Cyperi, 300g of Rhizoma Rhizoma Rhizoma, and 900g of cassia; For 1 hour, the two extracts were combined and concentrated to obtain the drug extract;

[0040] Step 2: Weigh 95g of sodium polyacrylate, 72g of ceramic powder, 8.71g of aluminum glycylate, and 2.62g of disodium edetate into 1540g of glycerin, and stir for 5 minutes under the condition that the vacuum degree is not lower than -0.06MPa. Obtain the glycerol phase and set aside;

[0041] Step 3: Take 1400ml of purified water, add 9.50g of tartaric acid and 215g of povidone, stir until it dissolves evenly, and obtain the water phase, set aside;

[0042] Step 4: Dissolve 7.28g of paraben preservative in 10ml of 95% ethanol, stir until it dissolves evenly, and obtain the ethanol phase;

[0043] Step 5: Add the ethanol phase obtained in step 4, 350 g of the drug extract obtained in step 1, and t...

Embodiment 2

[0046] Step 1: Weigh 1100g of Artemisia argyi leaves, 1200g of Jiyateng, 900g of dogwood, 600g of cassia twig, 800g of Rhizoma Cyperi, 600g of Rhizoma Rhizoma Rhizome, 600g of cinnamon; coarsely grind, and reflux extraction twice with 80% ethanol 10 times the mass of the medicinal material mixture, each time After 1.5 hours, the two extracts were combined and concentrated to obtain the drug extract;

[0047] Step 2: Weigh 126g of sodium polyacrylate, 80g of ceramic powder, 9.15g of aluminum glycylate, and 2.70g of disodium edetate into 1590g of glycerin, and stir for 8 minutes under the condition that the vacuum degree is not lower than -0.06MPa. Obtain the glycerol phase and set aside;

[0048] Step 3: Take 1600ml of purified water, add 10.15g of tartaric acid and 246g of povidone, stir until it dissolves evenly, and obtain the water phase for later use;

[0049] Step 4: Dissolve 7.68g of paraben preservative in 12ml of 95% ethanol, stir until it dissolves evenly, and obtain...

Embodiment 3

[0053] Step 1: Weigh 1500g of Artemisia argyi leaves, 1000g of sage vine, 1200g of dogwood, 300g of cassia twigs, 900g of Cyperus cyperi, 900g of Peucedanum chinensis, and 300g of cinnamon; coarsely crush them, and reflux extract twice with 85% ethanol that is 12 times the mass of the medicinal material mixture. After 2 hours, the two extracts were combined and concentrated to obtain the drug extract;

[0054] Step 2: Weigh 142g of sodium polyacrylate, 98g of ceramic powder, 9.75g of aluminum glycylate, and 2.75g of disodium edetate into 1650g of glycerin, and stir for 10 minutes under the condition that the vacuum degree is not lower than -0.06MPa. Obtain the glycerol phase and set aside;

[0055] Step 3: Take 1800ml of purified water, add 11.00g of tartaric acid and 275g of povidone, stir until it dissolves evenly, obtain the water phase, and set aside;

[0056] Step 4: Dissolve 7.70 g of paraben preservative in 15 ml of 95% ethanol, stir until it dissolves evenly, and obta...

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Abstract

The invention discloses a Chinese medicine for treating women dysmenorrhea. The Chinese medicine comprises the following compositions in percentage by weight: 10.25-39.48% of folium artemisiae argyi, 12.78-39.48% of paederia scandens, 7.69-31.58% of dogwood, 3.84-23.68% of cassia twig, 7.69-23.68% of rhizoma cyperi, 3.84-23.68% of rhizoma corydalis and 2.56-23.68% of cinnamon. The preparation method of an external patch of the Chinese medicine comprises the steps of: mixing the medicinal herbs extract with the accessory preparing a hydrogel patch to obtain a carrier cream, and coating, cutting, standing, moisture absorbing, quality testing, packaging, etc. According to the therapeutic formula of warming channel and expelling cold, activating blood and eleminating stasis, dredging meridian and relieving pain, as well as tonifying essence and blood, the invention selects Chinese herbal medicines on the basis of the reasons of women dysmenorrhea and the body physiological characteristics, combined with clinical application experiences, and the research results of pathology and modern Chinese medicine pharmacology, which improves treatment effect. The Chinese medicine for treating women dysmenorrhea and the preparation method of the external patch of the Chinese medicine disclosed by the invention have the advantages of large medicine loading capacity of external patches, high medicine transdermal absorption efficiency, and no irritating and allergic effects for skins.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine for treating female dysmenorrhea, and also relates to a preparation method of the traditional Chinese medicinal patch for external use. Background technique [0002] Dysmenorrhea is a common and frequently-occurring disease in gynecology. It is a menstrual disease mainly manifested by periodic lower abdominal pain during menstruation or before and after menstruation, or painful lumbosacral pain or even severe pain and fainting. The incidence of dysmenorrhea among women in my country is about 3.1%. Dysmenorrhea occurs with the menstrual cycle. In severe cases, it may be accompanied by nausea and vomiting, cold sweat, cold hands and feet or even fainting, which seriously affects daily work, study and life. According to clinical statistics, more than 30% of breast hyperplasia diseases are caused by dysmenorrhea, and the probability of deve...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8905A61K9/70A61P15/00
Inventor 李伟泽赵宁
Owner XIAN MEDICAL UNIV
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