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Blood lipid-lowering, AS-resisting and platelet aggregation-inhibiting drug and its preparation method

A technology for reducing blood lipids and drugs, which is applied in the field of blood lipid-lowering anti-AS anti-blood aggregation drugs and its preparation, which can solve the problems of not inhibiting blood aggregation, inhibiting blood aggregation without lowering blood lipids, and side effects

Inactive Publication Date: 2013-03-13
吴新治
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Currently used drugs for lowering blood lipids and inhibiting blood aggregation include statins, aspirin, dipyridamole, etc. Although they are very effective, they all have a single effect of lowering blood lipids, not inhibiting blood aggregation, and inhibiting blood aggregation does not lower blood lipids. Then it rises again, and long-term use has side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] (1) Preparation: Weigh 4g red ginseng silk according to the weight ratio of active ingredients, 24g fleece-flower root, 12g steamed Ligustrum lucidum, 12g salvia miltiorrhiza, 15g Ligusticum chuanxiong, 18g astragalus complanatus, 95% ethanol, 60% liquor, antiseptic Reagent and distilled water are reserved.

[0059] (2) Extraction and refining: Use the "alcohol extraction method" to extract the active ingredients from the raw materials ①red ginseng silk and Polygonum multiflorum, specifically ①Red ginseng silk and Polygonum multiflorum use 70% ethanol as the solvent, and use the "re-impregnation method" second Law group can mention. Prepare 4 steam filter tanks first, and install an electric stirrer in each tank for "fully enclosed" operation. First, grind the red ginseng silk and polygonum multiflorum into the No. 1 sieve, and then pass the No. 7 sieve to obtain fine powder and coarse powder for use. Put the ginseng powder into a can, add 70% ethanol and 10 times the we...

Embodiment 2

[0061] Example 2: Party A

[0062] (1) Preparation: Weigh 4g red ginseng silk according to the weight ratio of active ingredients, 18g fleece-flower root, 12g steamed Ligustrum lucidum, 12g salvia miltiorrhiza, 15g Ligusticum chuanxiong, 18g Astragalus complanatus, 50g garlic, 95% ethanol, 60% concentration Liquor, preservatives, and distilled water are reserved.

[0063] (2) Extraction and refining: The active ingredients are extracted from the raw materials ① red ginseng silk and Polygonum multiflorum with "alcohol extraction method", specifically according to the method of Example 1 [2] item 1 to obtain thick ointment A or powder A for use. ②Ligustrum lucidum, Danshen, Ligusticum chuanxiong and Astragalus complanatus were extracted with the "water extraction and alcohol precipitation method" to extract the active ingredients, and the thick ointment B or powder B was obtained according to the method in item 2 of Example 1 [2]. ③The effective ingredients of garlic are extracted b...

Embodiment 3

[0065] Embodiment 3: Party B

[0066] (1) Preparation: Weigh 4g red ginseng silk according to the weight ratio of the active ingredients, 18g fleece-flower root, 12g steamed Ligustrum lucidum, 12g salvia miltiorrhiza, 15g chuanxiong, 15g astragalus root, 12g cooked aconite, 15g astragalus, 15g peach kernel, garlic 50g and 95% ethanol, 60% liquor, preservatives, and distilled water are available for later use.

[0067] (2) Extraction and refining: Extract the active ingredients from the raw materials ①Red ginseng silk, Polygonum multiflorum and Astragalus extract, and obtain thick ointment A or powder A according to the method in item 1 of Example 1 [2]. ②Ligustrum lucidum, Salvia miltiorrhiza , Ligusticum chuanxiong and Astragalus complanatus were extracted with the "water extraction and alcohol precipitation method" to extract the active ingredients, and the thick paste B or powder B was obtained according to the method in item 2 of Example 1 [2]. ③The first extraction of the cook...

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Abstract

The invention discloses a blood lipid-lowering, AS (atherosclerosis)-resisting and platelet aggregation-inhibiting drug and its preparation method. The drug mainly adopts red ginseng tails, Radix Polygonum Multiflorum preparata, steamed Fructus Ligustri Lucidi, Salvia Miltiorrhiza, ligusticum wallichii, and Astragalus complanatus as raw materials, which are prepared into effective components respectively by an ''alcohol extraction method'' and an ''water extraction and alcohol precipitation method'', and then a pharmaceutically acceptable carrier or excipient is added to form the drug for oral administration. The drug and its preparation method provided in the invention are unique. The drug integrates the efficacy of blood lipid lowering, AS resisting, platelet aggregation inhibiting, fibrinolysis promoting and brain blood vessel dredging. Being able to lower blood lipid, resist AS and inhibit platelet aggregation, the drug is able to be used for blood lipid-lowering and platelet aggregation-inhibiting of the middle-aged and elderly people. Clinical experiments prove that the drug has good curative effects and has no toxic or side effect on the human body and internal organs.

Description

Technical field [0001] The present invention relates to the field of traditional Chinese medicine, in particular to a medicine for reducing blood lipids, resisting AS and inhibiting blood aggregation and a preparation method thereof. Background technique [0002] Stroke is a common and frequently-occurring disease of blood vessels in the elderly. Hyperlipidemia and platelet aggregation form thrombosis are important factors in the occurrence of stroke. Hypertension is the main risk factor in causing brain rate. The cause of hypertension is: long-term deviation of blood lipids High blood pressure, high blood lipids and platelet aggregation adhere to the blood vessel wall, proliferate vascular endothelial cells, produce atherosclerosis in arteries and sinuses, harden the arterial tube and lose its buffering effect, increasing blood pressure. The reason for the increase in blood lipids is that after people reach middle age (40-50 years old), the functions of the five internal organs ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/704A61K36/73A61K36/8962A61P3/06A61P39/06A61K35/62A61K35/64
Inventor 吴新治
Owner 吴新治
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