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Application of cinnamon oil for preparing medicine for treating arrhythmia and medicine prepared by cinnamon oil

A technology for arrhythmia and anti-arrhythmia, applied in drug combinations, pharmaceutical formulas, plant raw materials, etc., can solve the problems of lack of systematic research, screening and expanding the number of clinical research cases, failure to follow the research ideas of evidence-based medicine, etc. To achieve the effect of prolonging the survival time, improving the dissolution time limit, and large specifications

Inactive Publication Date: 2013-03-06
陕西中药研究所
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In recent years, single traditional Chinese medicines have achieved certain clinical curative effects and experimental results in the treatment of arrhythmias, but there is still a lack of systematic research, and it has not been possible to screen and expand the scope of clinical research from the aspects of the meridian distribution of the medicine, the four qi and five flavors, and the dismantling of classic prescriptions. The number of cases failed to follow the research ideas of evidence-based medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] The preparation method of cinnamon oil dripping pills comprises the following steps:

[0036] (1) The ratio of drug to matrix is ​​1:9. Take 1 part of cinnamon oil raw material and mix it with 9 parts of matrix. The matrix is ​​made by mixing polyethylene glycol 6000: stearic acid (8.5:0.5).

[0037] (2) Melt the matrix in a water bath at 80°C, then add the raw material of cinnamon oil, and stir clockwise continuously until evenly.

[0038] (3) Put the uniformly stirred liquid medicine into the dripping tank of the dropping pill machine, control each parameter according to the dripping pill making conditions, fully stir evenly in the dripping tank, and wait until each control index chassis of the dropping pill machine After the temperature is 80°C, the oil bath temperature is 80°C, the liquid temperature is 80°C, and the dripping temperature is 80°C, the dripping starts after the parameters are stable.

[0039] (4) The preparation of dripping pills is prepared on a dri...

Embodiment 2

[0042] A method for preparing cinnamon oil dripping pills, comprising the following steps:

[0043] (1) The ratio of drug to matrix is ​​1:8. Take 1 part of cinnamon oil raw material and mix it with 8 parts of matrix, where the matrix is ​​polyethylene glycol 4000.

[0044] (2) Melt the matrix in a 70°C water bath, then add the cinnamon oil raw material, and stir clockwise continuously until evenly.

[0045] (3) Put the uniformly stirred liquid medicine into the dripping tank of the dropping pill machine, control each parameter according to the dripping pill making conditions, fully stir evenly in the dripping tank, and wait until each control index chassis of the dropping pill machine After the temperature is 70°C, the oil bath temperature is 70°C, the liquid temperature is 70°C, and the dripping temperature is 70°C, etc. meet the requirements, the dripping starts after the parameters are stable.

[0046] (4) The preparation of dripping pills is prepared on a dripping pill p...

Embodiment 3

[0049] A method for preparing cinnamon oil dripping pills, comprising the following steps:

[0050] (1) The ratio of drug to matrix is ​​1:4. Take one part of cinnamon oil raw material and mix it with 4 parts of matrix, where the matrix is ​​polyethylene glycol 6000.

[0051] (2) Melt the matrix in a water bath at 75°C, then add the raw material of cinnamon oil, and stir clockwise continuously until evenly.

[0052] (3) Put the uniformly stirred liquid medicine into the dripping tank of the dropping pill machine, control each parameter according to the dripping pill making conditions, fully stir evenly in the dripping tank, and wait until each control index chassis of the dropping pill machine After the temperature is 75°C, the oil bath temperature is 75°C, the liquid temperature is 75°C, and the dripping temperature is 75°C, etc. meet the requirements, the dripping starts after the parameters are stable.

[0053] (4) The preparation of dripping pills is prepared on a drippin...

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Abstract

The invention discloses an application of cinnamon oil for preparing a medicine for treating arrhythmia and the medicine prepared by the cinnamon oil. The main component cinnamyl aldehyde in the cinnamon oil can improve the perfusion pressure of the coronary artery and the cerebral artery correspondingly to accelerate the collateral circulation of the cardiac muscle to be opened, so that blood supply of the cardiac muscle is changed to protect the cardiac muscle, therefore, the cinnamon oil has the effect of preventing arrhythmia. The cinnamon oil dropping pill provided by the invention has the effect of preventing arrhythmia, improving myocardial ischemia and resisting hypoxia, and the cinnamon oil can be applied to preparing the medicine for treating arrhythmia.

Description

technical field [0001] The invention belongs to the technical field of drugs for treating arrhythmia, and relates to the application of cinnamon oil in the preparation of drugs for treating arrhythmia and the prepared drugs. Background technique [0002] Arrhythmia is a common clinical disease, frequently-occurring disease. Cardiac arrhythmia refers to a type of disease that results in tachycardia, bradycardia, arrhythmia or ectopic heart rhythm caused by abnormal heart self-discipline or excitation conduction disorder. 11%. According to statistics, about 600,000 people die of sudden cardiac death in my country every year, 90% of which are caused by malignant arrhythmia. Therefore, the treatment of arrhythmia has become the focus of attention of medical workers. [0003] Clinically, the Western medicine treatment of arrhythmia has the characteristics of rapid action and definite curative effect, but its side effects are relatively large, and it is easy to relapse and cause...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/54A61K9/20A61P9/10A61P9/06
Inventor 同卓斌朱爱华王四旺张丽军秦永刚原燕胡少婷倪亚会
Owner 陕西中药研究所
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