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Traditional Chinese medicine composition for improving anoxia endurance as well as preparation method and application thereof

A composition and tolerance technology, which is applied in the direction of drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve the problems of inconvenient taking, large toxic and side effects, etc., to improve hypoxia tolerance, compatibility Rigorous, well-designed effects

Inactive Publication Date: 2013-02-20
XINXIANG MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] There are many drugs and supplements that are clinically used to improve hypoxia tolerance, but these varieties have relatively large toxic and side effects, and are inconvenient to take. So far, people are looking for a traditional Chinese medicine that is simple to make and easy to take to improve hypoxia tolerance.

Method used

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  • Traditional Chinese medicine composition for improving anoxia endurance as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Embodiment 1: the preparation of granule

[0027] Take 30g of Astragalus membranaceus, 20g of Xiantao grass, 25g of Codonopsis pilosula, 10g of Tribulus terrestris, 30g of iron leech, and 10g of Jiulixiang. Add water for 6 times the weight of the medicinal material, decoct for 1 hour, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.10 (65°C), add an appropriate amount of ethanol to make the alcohol content (volume fraction) reach 65%, stir, and statically Set aside for 24 hours, filter, recover ethanol from the filtrate and concentrate to extract with a relative density of 1.10 (65°C), and spray dry (conditions are that the inlet air temperature is 100°C, the outlet air temperature is 80°C, and the material temperature is 70°C. Atomization pressure is 0.2 MPa, spray speed is 5ml / s.), crushed into dry extract powder, then add appropriate amount of dextrin, moisten with appropriate amount of 80% ethanol, make soft material, granulate...

Embodiment 2

[0028] Embodiment 2: the preparation of tablet

[0029] Take 20g of astragalus, 30g of fairy peach grass, 20g of Codonopsis pilosula, 20g of Tribulus terrestris, 20g of iron leech, and 20g of Jiulixiang medicinal materials, add water to decoct twice, add water for the first time to 10 times the weight of the medicinal materials, decoct for 2 hours, Add water to 8 times the weight of the medicinal material, decoct for 1 hour, combine the decoction, filter, concentrate the filtrate to a relative density of 1.15 (65°C), add an appropriate amount of ethanol to make the alcohol content (volume fraction) reach 75%, stir, and let stand After 24 hours, filter, recover ethanol from the filtrate and concentrate it to an extract with a relative density of 1.25 (65°C), spray dry (conditions are that the inlet air temperature is 120°C, the outlet air temperature is 90°C, the material temperature is 80°C, and the mist The pressure is 0.3 MPa, the spray speed is 7.5 / s.), crushed into dry ext...

Embodiment 3

[0031] Take 10g of Astragalus membranaceus, 40g of Xiantao grass, 15g of Codonopsis pilosula, 30g of Tribulus terrestris, 10g of iron leech, and 30g of Jiulixiang medicinal materials, add water to boil twice, add water for the first time to 12 times the weight of the medicinal materials, boil for 2 hours, and the second time Add water to 10 times the weight of the medicinal material, decoct for 2 hours, combine the decoction, filter, and concentrate the filtrate to a relative density of 1.20 (65°C), add an appropriate amount of ethanol to make the alcohol content (volume fraction) reach 85%, stir, and let stand After 24 hours, filter, recover ethanol from the filtrate and concentrate to extract with a relative density of 1.30 (65°C), add water, sucrose, and 0.1% sodium benzoate to obtain a finished oral liquid.

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Abstract

The invention discloses a traditional Chinese medicine composition for improving anoxia endurance. The traditional Chinese medicine composition comprises the following components: 10 to 30 parts of astragalus mongholicus, 20 to 40 parts of purslane speedwell herb, 15 to 25 parts of codonopsis pilosula, 10 to 30 parts of caltrop, 10 to 30 parts of asplenium antiquum makino, and 10 to 30 parts of murraya paniculata. The traditional Chinese medicine composition is in form of granula, tablet, oral liquid and capsula. The invention also discloses a preparation method of the traditional Chinese medicine composition. The preparation method comprises the following steps: adding water to decoct; concentrating; implementing alcohol precipitation; carrying out spray drying; crushing the obtained particles into dried extract powder; and adding auxiliary materials to prepare into the requested preparation. The invention also discloses application of the traditional Chinese medicine composition in preparation of medicine for improving anoxia endurance.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine composition for improving hypoxia tolerance, a preparation method and application thereof. Background technique [0002] Oxygen is the key substance for human body to carry out metabolism, and it is the first need of human life activities. Oxygen inhaled by the lungs is transformed into available blood oxygen in the human body, and the blood carries blood oxygen to the whole body to input the energy required for biological oxidation. Therefore, oxygen is an indispensable and important substance in normal life activities. Adults consume about 250ml of oxygen per minute in a resting state, and the oxygen consumption increases significantly when they are active. The normal oxygen reserve in the body (including the oxygen stored in the alveoli and combined with hemoglobin and globin) is only about 1.5L. When breathing...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/75A61P39/00A61K35/64
Inventor 不公告发明人
Owner XINXIANG MEDICAL UNIV
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