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Chinese medicinal composition for treating dermatosis and preparation method and application thereof

A composition and technology for skin diseases, applied in the directions of skin diseases, drug combinations, pharmaceutical formulations, etc., can solve the problems of easy recurrence, heavy economic burden on patients, strong drug dependence, etc., and achieve the effect of simple preparation

Active Publication Date: 2013-02-06
山东新宝医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At the same time, due to the recurrent outbreak of the disease, repeated treatment is often required, which also brings a heavy economic burden to the patient.
[0004] Nowadays, there are many medicines for the treatment of vitiligo and psoriasis, both traditional Chinese medicine and western medicine. Although they can all play a certain role, they cannot be cured, and they are prone to relapse and strong drug dependence.

Method used

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  • Chinese medicinal composition for treating dermatosis and preparation method and application thereof
  • Chinese medicinal composition for treating dermatosis and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Take 36 parts of vernonia, 36 parts of psoralen, 18 parts of angelica, 18 parts of schisandra (wine) and 12 parts of plumbago, and make capsules according to the following method:

[0038] (1) Crush the insect repellent Vernonia into fine powder, set aside;

[0039] (2) The rest of the medicinal materials were extracted 3 times with 8 times the amount of 75vol% ethanol, the first time was 2 hours, the second time was 1 hour, the second time was 1 hour, the extracts were combined, filtered, and the filtrate was concentrated to a relative density of 1.20~ 1.30 (70°C) thick paste;

[0040] (3) Mix the insect repellent Vernonia fine powder with the above-mentioned thick paste, and dry to obtain a dry paste;

[0041] (4) Grind the dry paste into fine powder, add appropriate amount of pharmaceutical excipients, mix evenly, granulate, dry, add 1% magnesium stearate, mix evenly, pack into capsules, that is, 0.5g per capsule.

Embodiment 2

[0043] Take 30 parts of vernonia, 60 parts of psoralen, 15 parts of angelica, 20 parts of schisandra (wine) and 10 parts of plumbago, and make capsules according to the following method:

[0044] (1) Crush the insect repellent Vernonia into fine powder, set aside;

[0045] (2) The remaining medicinal materials were extracted twice with 6 times the amount of 80vol% ethanol, each time for 2 hours, the extracts were combined, filtered, and the filtrate was concentrated to a thick paste with a relative density of 1.25-1.35 (60°C);

[0046] (3) Mix the medicinal material fine powder with the above-mentioned thick ointment, and dry to obtain a dry ointment;

[0047] (4) Grind the dry paste into fine powder, add appropriate amount of pharmaceutical excipients, mix well, granulate, dry, add 0.5% magnesium stearate, mix well, pack into capsules, and get it, each capsule contains 0.5g.

Embodiment 3

[0049] Take 60 parts of vernonia, 30 parts of psoralen, 30 parts of angelica, 10 parts of schisandra (wine) and 20 parts of plumbago, and make capsules according to the following method:

[0050] (1) Crush the insect repellent Vernonia into fine powder, set aside;

[0051] (2) The remaining medicinal materials were extracted twice with 12 times the amount of 65vol% ethanol, each time for 2 hours, the extracts were combined, filtered, and the filtrate was concentrated to a thick paste with a relative density of 1.30-1.35 (80°C);

[0052] (3) Mix the medicinal material fine powder with the above-mentioned thick ointment, and dry to obtain a dry ointment;

[0053] (4) Grind the dry paste into fine powder, add appropriate amount of pharmaceutical excipients, mix well, granulate, dry, add 0.8% magnesium stearate, mix well, pack into capsules, and get it, each capsule contains 0.5g.

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Abstract

The invention discloses a Chinese medicinal composition for treating dermatosis. The Chinese medicinal composition comprises the following raw materials in parts by weight: 30-60 parts of vernonia anthelmintica, 30-60 parts of malaytea scurfpea fruit, 15-30 parts of Chinese angelica, 10-20 parts of Chinese magnoliavine fruit (alcohol-treated) and 10-20 parts of plumbago zeylanica. The invention further provides a preparation method and an application of the Chinese medicinal composition. The medicament is easy to prepare, is prepared from vernonia anthelmintica and malaytea scurfpea fruit serving as major raw materials and other medicinal components, and has the effects of activating blood, cooling blood, expelling wind, clearing away cold, dissipating blood stasis, killing parasites and curing ringworms; and pathogenesis of vitligo and psoriasis are eliminated fundamentally, focuses of infection are eliminated directly, and the aim of curing is fulfilled.

Description

Technical field [0001] The invention involves a drug for skin diseases, which specifically involves a traditional Chinese medicine composition that treats vitiligo and psoriasis, which belongs to the field of pharmaceutical technology. Background technique [0002] Vitiligo (Vitiligo) is an acquired melanin loss of skin disease. It is clinically manifested as pigmentation with different sizes and different shapes. The number is uncertain and the edges are clear.The white spots of vitiligo can occur in any part of the body, but the skin of the skin such as the exposed parts such as the face, the neck, the back of the hand and the external genitals is more common. Because the exposure of the white spots to the visual part will affect the patient's appearance, and then it will affect the appearance of the patient, and then it will affect the appearanceThe normal life of patients has caused a lot of psychological pressure, so there are a lot of people who seeks, and they are very urg...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/57A61K36/8945A61K36/9062A61K36/90A61K36/736A61K36/804A61K36/704A61P17/00A61P17/06A61K35/56A61K35/618
Inventor 许东升韩丽丽马全龙谢晓燕刘永霞王庆生王浩骅孙山
Owner 山东新宝医药有限公司
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