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Tilianin microemulsion composition

A technology of microemulsion and stellin, which is applied in the field of stellin microemulsion composition, can solve problems such as increasing solubility, and achieve the effect of simple preparation method

Inactive Publication Date: 2013-01-09
石河子大学医学院第一附属医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The Chinese patent announcement number is CN10178345A discloses the preparation method of stellin, but, the shortcoming of this method is, does not provide a kind of increase to meet the requirement of preparation for the disclosed stellin according to the water-insoluble property. Solubility method

Method used

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Examples

Experimental program
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Effect test

Embodiment 1

[0011] Stellin: 0.2 parts, polyoxyethylene hydrogenated castor oil: 5 parts, polyethylene glycol-400: 10 parts, isopropyl myristate: 10 parts, water: 30 parts

Embodiment 2

[0013] Stellin: 0.2 parts, lecithin: 9 parts, ethanol: 9 parts, ethyl oleate: 10 parts, water: 20 parts

Embodiment 3

[0015] Tianjiin: 0.4 parts, Tween-80: 10 parts, Propylene Glycol: 5 parts, Ethyl Oleate: 10 parts, Water: 10 parts

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PUM

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Abstract

The invention discloses a microemulsion composition containing tilianin. The microemulsion composition comprises tilianin, an emulsifier, a co-emulsifier, oil and water. The microemulsion composition can greatly enhance the solubility of the tlianin.

Description

technical field [0001] The invention relates to a stellin microemulsion composition capable of significantly increasing the solubility of scinnamon. Background technique [0002] Tintin is an important flavonoid glycoside compound extracted from the Lamiaceae plant Cymbidium chinensis, which has biological activities such as anti-atherosclerosis, anti-hypertension, and myocardial protection. Stinin is a weak acid drug, insoluble in water, easily soluble in acetonitrile, dimethyl sulfoxide, methanol, chloroform, ethyl acetate and other organic solvents. The poor water solubility of stellin limits the effective development and utilization of its preparations. [0003] The Chinese patent announcement number is CN10178345A discloses the preparation method of stellin, but, the shortcoming of this method is, does not provide a kind of increase to meet the requirement of preparation for the disclosed stellin according to the insoluble property of stellin Solubility method. Cont...

Claims

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Application Information

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IPC IPC(8): A61K9/107A61K31/7048A61K47/44A61K47/24A61K47/34A61P9/10A61P9/12
Inventor 王新春邢建国袁勇韩博李静王晓义
Owner 石河子大学医学院第一附属医院
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