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Medicinal granule with whitening effect and preparation method thereof

A granule and efficacy technology, which is applied in the field of granules and preparations with whitening effect, can solve the problems such as the appearance of spots and the inability to effectively inhibit the re-growth of melanin, and achieve the effect of removing pigment spots, reducing skin pigmentation, and good taste

Active Publication Date: 2012-12-26
ANHUI YANZHIFANG FOOD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The current whitening products are mainly for external use. Although external whitening products can eliminate the melanin on the surface, because the whitening ingredients have not penetrated into the inner layer of the skin, they cannot effectively inhibit the re-growth of melanin, so the spots will reappear after a period of time

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Prepare the following raw materials in parts by weight

[0047]White peony 70, rose 10, saponins thorn 75, windproof 30, sealwort 60, licorice 20, mulberry 70, ginseng flower 20, heterophylla 30, jujube seed 60, rose fruit extract 10, vitamin C20, vitamin E10, Arbutin 20, grape seed extract 20, excipients 30.

[0048] Its preparation method comprises the following steps:

[0049] 1) Extract Twice of Radix Paeoniae Alba, Rose, Saponin, Fangfeng, Polygonatum, Licorice, Angelica, Mulberry, Ginseng Flower, Pseudostellaria Pseudostellariae, add 40% ethanol 7 times the amount of the raw material for the first extraction for 1 hour, filter , to obtain the filtrate; for the second time, add 8 times the amount of water of the crude drug and extract for 1 hour, filter to obtain the filtrate; combine the two filtrates, filter through 100 mesh, concentrate under reduced pressure to a relative density of 0.9, and spray with a spray drier After drying, the inlet air temperature ...

Embodiment 2

[0054] Prepare the following raw materials in parts by weight:

[0055] White peony 80, rose 12, saponins thorn 12, windproof 38, sealwort 70, licorice 30, mulberry 90, ginseng flower 30, heterophylla 30, jujube seed 50, rose fruit extract 15, vitamin C30, vitamin E35, Arbutin 30, grape seed extract 20, excipients 20.

[0056] Its preparation method comprises the following steps:

[0057] 1) Extract twice the Radix Paeoniae Alba, Rose, Saponaria thorn, Fangfeng, Polygonatum, Licorice, Angelica, Mulberry, Ginseng Flower, Pseudostellaria Pseudostellariae, add 8 times the amount of raw material 40% ethanol for the first extraction for 1.5 hours, filter , to obtain the filtrate; the second time, add 8 times the amount of water to extract the raw material drug for 2 hours, filter to obtain the filtrate; combine the two filtrates, filter through 100 mesh, concentrate under reduced pressure to a relative density of 1.1, and spray with a spray drier After drying, the inlet air tempe...

Embodiment 3

[0062] Prepare the following raw materials in parts by weight

[0063] White peony 90, rose 15, saponins thorn 15, windproof 50, sealwort 90, licorice 30, mulberry 90, ginseng flower 60, heterophylla 50, jujube seed 90, rose fruit extract 15, vitamin C40, vitamin E40, Arbutin 30, grape seed extract 40, excipients 30.

[0064] Its preparation method comprises the following steps:

[0065] 1) Extract Twice of Radix Paeoniae Alba, Rose, Saponin, Fangfeng, Polygonatum, Licorice, Angelica, Mulberry, Ginseng Flower, Pseudostellaria Pseudostellariae, add 40% ethanol 8 times the amount of the raw material for the first extraction for 2 hours, filter , to obtain the filtrate; for the second time, add 9 times the amount of water to extract the raw material drug for 3 hours, filter to obtain the filtrate; combine the two filtrates, filter through 100 mesh, concentrate under reduced pressure to a relative density of 1.2, and spray with a spray drier After drying, the inlet air temperatu...

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Abstract

The invention discloses a medicinal granule with a whitening effect and a preparation method thereof. The medicinal granule comprises the following raw materials in parts by weight: 70-90 parts of white paeony root, 9-15 parts of rose, 7-15 parts of Chinese honeylocust spine, 30-50 parts of divaricate saposhnikovia root, 60-90 parts of sealwort, 20-30 parts of liquoric root, 70-90 parts of mulberry, 20-60 parts of ginseng flower, 10-50 parts of heterophylly falsestarwort root, 40-90 parts of spina date seed, 10-15 parts of fruit of rosa davurica pall extract, 10-50 parts of vitamin C, 10-50 parts of vitamin E, 20-30 parts of arbutin, 20-40 parts of grape seed extract and 10-30 parts of auxiliary materials. Due to the adoption of the medicinal granule, the defects of external whitening products are overcome, and the growth of melanin is inhibited radically; moreover, unique Chinese medicinal materials are selected, raw materials are combined in a compatible way, and active ingredients such as vitamins and the like are adopted, so that a good synergic action is achieved; and the medicinal granule has good mouthfeel, the problem of poor mouthfeel of the conventional health-care beverage is solved, and the aim of whitening through the medicinal granule in daily life is fulfilled.

Description

technical field [0001] The invention relates to a granule and a preparation method thereof, in particular to a granule with whitening effect and a preparation method thereof. Background technique [0002] Asians like to pursue healthy and fair skin. The skin tissue is the first protective barrier of the human body. It is broadly divided into three parts: epidermis, dermis and subcutaneous tissue. The color of the skin is mainly determined by the quantity, size and distribution of melanin contained in the skin cells. For skin whitening, we need to start with cell whitening. For intracellular whitening, we should first prevent the synthesis of melanin. In this regard, there are many studies on the inhibition of tyrosinase activity. Tyrosinase is a polyphenolase that belongs to the class of oxidoreductases, which can catalyze the oxidation of tyrosine into dopa and dopaquinone and the formation of 5,6-dihydroxyindole carboxylic acid from dopachrome , producing melanin. Beca...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61K9/16A61P17/00A61K31/7034A61K31/375A61K31/355
Inventor 张丽琍祁斌吴雷张超
Owner ANHUI YANZHIFANG FOOD
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