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Rhizoma dryopteris crassirhizomae and fructus crataegi composition, preparation method and application of composition

A technology for absorbing all kinds of ingredients and compositions, which is applied in the field of medicine and achieves the effects of low cost, making up for insufficient immune protection and improving competitiveness.

Active Publication Date: 2012-12-12
CHINA AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are no reports about the combination of Mianma Guanzhong and Hawthorn, and the compatibility of the extracts of the two formulations at home and abroad, and there is no report on the efficacy of compatibility in the prevention and treatment of viral diseases in livestock and poultry

Method used

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  • Rhizoma dryopteris crassirhizomae and fructus crataegi composition, preparation method and application of composition
  • Rhizoma dryopteris crassirhizomae and fructus crataegi composition, preparation method and application of composition
  • Rhizoma dryopteris crassirhizomae and fructus crataegi composition, preparation method and application of composition

Examples

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Effect test

Embodiment 1

[0035] The following examples are used to illustrate the present invention, but not to limit the scope of the present invention. Example 1 Preparation of granules of the present invention

[0036] (1) Weigh 4g of Mianmaguanzhong and 6g of hawthorn, and crush them into coarse powder.

[0037] (2) Take the Mianma Guanzhong coarse powder prepared in step (1), soak it in 4 times the volume of ethyl acetate for 24 hours, collect the extract, and recover the ethyl acetate to obtain the extract; add 4 times 75% ethanol to the medicine residue Soak for 2h, boil for 1h, extract twice, combine the filtrate, rotary evaporate the filtrate, and concentrate under reduced pressure to obtain the extract. Mix the extract collected twice for use.

[0038] (3) Take the hawthorn coarse powder prepared in step (1), soak it with 4 times the volume of ethyl acetate for 24 hours, then recover the ethyl acetate to obtain an extract; the medicine residue is soaked with 4 times the volume of 75% ethanol for ...

Embodiment 2

[0041] Example 2 Preparation of the soluble powder of the present invention

[0042] (1) Weigh 4g of Mianmaguanzhong and 6g of hawthorn, and crush them into coarse powder.

[0043] (2) Take the Mianma Guanzhong coarse powder prepared in step (1), soak it in 6 times the volume of ethyl acetate for 48 hours, collect the extract, and recover the ethyl acetate to obtain the extract; add 4 times 85% ethanol to the medicine residue Soak for 4 hours, boil for 2 hours, extract twice, combine the filtrate, rotary evaporate the above filtrate, and concentrate under reduced pressure to obtain an extract. Mix the extract collected twice for use.

[0044] (3) Take the hawthorn coarse powder prepared in step (1), soak it with 6 times the volume of ethyl acetate for 48 hours, then recover the ethyl acetate to obtain an extract; the medicine residue is soaked with 4 times the volume of 95% ethanol for 4 hours, and then boiled for extraction 2h, pour out the extract and filter with suction to obtai...

Embodiment 3

[0046] Example 3 Preparation of tablets of the invention

[0047] (1) Weigh 5g of Mianmaguanzhong and 5g of hawthorn, and crush them into coarse powder.

[0048] (2) Take the Mianma Guanzhong coarse powder prepared in step (1) and soak it in 8 times the volume of ethyl acetate for 24 hours, collect the extract and recover the ethyl acetate to obtain the extract; add 8 times of 95% ethanol to the medicine residue Soak for 2h, boil for 1h, extract twice, combine the filtrate, rotary evaporate the filtrate, and concentrate under reduced pressure to obtain the extract. Mix the extract collected twice for use.

[0049] (3) Take the hawthorn coarse powder prepared in step (1), soak it in 8 times the volume of ethyl acetate for 24 hours, then recover the ethyl acetate to obtain the extract; the medicine residue is soaked in 8 times the volume of 95% ethanol for 2 hours, and then boil for extraction 2h, pour out the extract and filter with suction to obtain a supernatant for use, combine t...

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Abstract

The invention relates to a rhizoma dryopteris crassirhizomae and fructus crataegi composition, a preparation method and an application of the composition. The effective components of the composition provided by the invention are prepared from the following raw materials by weight: 10-90 parts of rhizoma dryopteris crassirhizomae and 10-90 parts of fructus crataegi. The rhizoma dryopteris crassirhizomae and fructus crataegi composition provided by the invention is good in effect of preventing and treating poulty viral diseases, in particular to the poultry diseases caused by bursal disease viruses, the poultry kidney diseases caused by renal type infectious bronchitis viruses, the influenza virus A diseases of mammals caused by avian influenza viruses and the poultry avian influenza virus diseases; and the rhizoma dryopteris crassirhizomae and fructus crataegi composition provided by the invention has the characteristics of being more liable to obtain the raw materials, good in curative effect, free of residues, green and environment-friendly and the like, so that the composition can replace the chemical antiviral drugs.

Description

Technical field [0001] The invention belongs to the field of medicine, and relates to a Mianma Guanzhong hawthorn composition, a preparation method and application thereof. Background technique [0002] There are many types of animal diseases and widespread epidemics in our country. The frequent occurrence of viral diseases has a serious impact on the social economy and people's lives. According to relevant data, my country's annual direct economic losses caused by viral diseases are as high as 20-25 billion yuan, which is about 2.5%-3.1% of the total output value of animal husbandry. From the perspective of indirect losses, the resulting reduction in animal production performance, decline in the quality of livestock products, increase in feed consumption, artificial waste, increase in prevention and control costs, environmental damage, and economic losses in related industries are even greater. It is estimated that the loss caused by illness and death 3 to 5 times of that. The...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/734A61P31/12A61P31/14A61P31/16A61K36/11
Inventor 何诚杨群辉张钰
Owner CHINA AGRI UNIV
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