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Method for acquiring geometric correction parameter of PET (positron emission tomography) system

A geometric correction and parameter technology, applied in the field of obtaining PET system geometric correction parameters, can solve the problems of inflexibility, complicated operation process, economic cost, time and manpower consumption, etc., to ensure accuracy, speed up design, and simple process Effect

Active Publication Date: 2012-11-21
SHANGHAI RES CENT OF BIOMEDICAL ENG
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  • Claims
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Problems solved by technology

[0006] Because the acquisition method of the above-mentioned known geometric correction parameters needs to establish an actual measurement environment (such as needing a set of actual PET system that can work normally, need to customize a special measured physical model, etc.), the operation process is complicated when measuring data, economic cost, time and manpower consumption are large, not flexible enough
In addition, the measured data contains scattering events and random events, and the actual system cannot accurately distinguish these events, and the geometric correction is only for the real event data, so the obtained geometric correction parameters will not be accurate enough

Method used

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  • Method for acquiring geometric correction parameter of PET (positron emission tomography) system
  • Method for acquiring geometric correction parameter of PET (positron emission tomography) system
  • Method for acquiring geometric correction parameter of PET (positron emission tomography) system

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Embodiment 1

[0029] This embodiment provides a method for obtaining the geometric correction parameters of the PET system. The method is based on computer simulation, and a virtual PET system identical to the actual PET system is constructed by software, and a specially designed virtual object under test is performed in the virtual PET system. Scan to obtain the relevant coincidence event data, and then go through the difference comparison analysis to obtain the geometric correction parameters.

[0030] The flow of the method for obtaining the geometric correction parameters of the PET system is as follows: figure 1 shown, including the following steps:

[0031] Step 102, constructing a virtual PET system environment by writing a set of computer software based on Monte Carlo simulation technology. The principle of Monte Carlo simulation technology is well known, and its accuracy and reliability have been confirmed by many scientific literatures. The computer software written in this embo...

Embodiment 2

[0042] The difference between the present embodiment and the first embodiment is that in step 102, a virtual PET system environment is constructed through open-source computer software, such as GATE (Geant4 Application for Tomographic Emission).

Embodiment 3

[0044] This embodiment verifies the effect of the method for obtaining geometric correction parameters of the PET system described in the first embodiment, and the verification process is as follows:

[0045] In an actual PET system, first scan the uniform cylindrical object to obtain the measured coincidence event data; then reconstruct the image according to the measured coincidence event data, and obtain the PET image map of the measured uniform cylinder. The gray value in the figure represents the radioactivity intensity. The larger the gray value of the area (white and bright image), the stronger the radioactive intensity of the area; the smaller the gray value of the area (dark image), the weaker the radioactive intensity of the area. Theoretically, the gray values ​​in the cross-sectional image of a uniform cylinder PET image are almost equal in a circular area. In other words, a circular area in the cross-sectional view is uniformly light and dark.

[0046] Such as ...

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Abstract

The invention discloses a method for acquiring a geometric correction parameter of a PET (positron emission tomography) system. The method comprises the steps of 1) building a virtual PET system environment by using computer software; 2) inputting the related parameter of a real PET system of which the geometric correction parameter needs to be measured into the virtual PET system environment; 3) designing a specific virtual measured object in the virtual PET system environment; 4) scanning the specific virtual measured object in the virtual PET system environment to acquire coincidence data; and 5) performing difference analysis to the coincidence data to obtain the geometric correction parameter. According to the method, preparation for object PET equipment and a measured object model is eliminated, and the process of acquiring the geometric correction parameter is simple, economical, quick and free from the limit of environment factor, and therefore, the accuracy of the geometric correction parameter is ensured. In addition, the method can be executed before or after development and production of the PET system, so that the design, development and production period of the PET system is accelerated.

Description

technical field [0001] The invention belongs to the technical field of medical imaging equipment, and relates to a method for obtaining geometric correction parameters of a PET system. Background technique [0002] Positron Emission Tomography (PET) system is a radionuclide tracer imaging system. Usually the detected object contains radionuclide-labeled tracer substances. Radionuclides emit positrons upon decay. The positron annihilates with a neighboring electron, producing a pair of 511KeV gamma (γ) photons flying in opposite directions. When the gamma photon is collected by a pair of PET detection units within a certain time window, an event mark is generated, which is called a coincidence event. The coincidence event records information such as the spatial position of the pair of PET detection units. Therefore, it can be determined that annihilation has occurred at a certain position on the connection line (referred to as coincidence line) between the pair of PET det...

Claims

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Application Information

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IPC IPC(8): G06F17/50A61B6/03
Inventor 张晓俞王新谢舒平
Owner SHANGHAI RES CENT OF BIOMEDICAL ENG
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