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Bitter glossy ganoderma composition for oncotherapy and preparation method of bitter glossy ganoderma composition

A composition and technology of Ganoderma lucidum, applied in the field of bitter Ganoderma lucidum composition and its preparation for tumor treatment, can solve the problems of human body toxicity and side effects, and achieve the effects of prolonging the life span, improving the quality of life, and widening the anti-cancer spectrum

Active Publication Date: 2012-11-14
朱卫
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Cancer is a disease that seriously threatens human life and health. Chemotherapy drugs, while acting on tumor cells, can also significantly inhibit the growth or kill normal human cells, especially fast-growing cells, resulting in extremely toxic side effects on the human body.

Method used

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  • Bitter glossy ganoderma composition for oncotherapy and preparation method of bitter glossy ganoderma composition
  • Bitter glossy ganoderma composition for oncotherapy and preparation method of bitter glossy ganoderma composition
  • Bitter glossy ganoderma composition for oncotherapy and preparation method of bitter glossy ganoderma composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0119] Embodiment 1 bitter Ganoderma lucidum capsule I every 1g

[0120] prescription:

[0121] Ganoderma lucidum 30g Astragalus 50g Poria cocos 50g Motherwort 50g Salvia 50g

[0122] Half branch lotus 50g White flower tongue snake grass 50g Dragon bud grass 50g Pueraria 50g

[0123] Preparation method: take each of the above-mentioned raw materials, mix them, dry them and grind them finely, pass them through a 100-mesh sieve for 4 times, sterilize them, and put 1g of each capsule into capsules.

Embodiment 2

[0124] Example 2 Bitter Ganoderma Lucidum Capsule II 0.5g per capsule

[0125] prescription:

[0126] Ganoderma lucidum 200g Astragalus 300g Poria cocos 300g Motherwort 300g Salvia 300g

[0127] Half branch lotus 300g White flower tongue snake grass 300g Dragon bud grass 300g Pueraria 700g

[0128] Preparation method:

[0129] Take each of the above-mentioned raw materials, crush them into coarse powder, soak them in 75% ethanol, heat and reflux for extraction for 5 hours, filter, recover the ethanol from the filtrate until the alcohol is tasteless, mix it with medicinal residues, add water to the mixture and decoct for 4 hours, filter , concentrating the filtrate into a liquid extract to obtain the bitter ganoderma composition, adding dextrin and starch to granulate, adding a lubricant, and putting it into capsules to obtain.

Embodiment 3

[0130] Example 3 Bitter Ganoderma Lucidum Capsule III 0.25g per capsule

[0131] prescription:

[0132] Ganoderma lucidum 400g Astragalus 700g Poria cocos 700g Motherwort 700g Salvia 700g

[0133] Half branch lotus 700g White flower tongue snake grass 700g Dragon bud grass 700g Pueraria 300g

[0134] Preparation method: take each of the above-mentioned raw materials, soak in water for 2 hours, then decoct with 8 times the amount of water for 3 times, 25 minutes each time, filter the decoctions and combine them, concentrate to obtain a concentrated solution; add ethanol to the concentrated solution Carry out alcohol precipitation, filter, recover ethanol from the filtrate until there is no alcohol smell, and then fine filter and sterilize the recovered solution to obtain the bitter Ganoderma lucidum composition, add dextrin and starch to granulate, add lubricant, and put it into capsules. .

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Abstract

The invention relates to a bitter glossy ganoderma composition for oncotherapy and a preparation method of the bitter glossy ganoderma composition. The composition is prepared by raw materials of 10-50 of glossy ganoderma, 10-100 of milkvetch roots, 10-100 of Indian buead, 10-100 of brittle falsepimpernel herbs, 10-100 of red-rooted salvia roots, 10-100 of barbated skullcup herbs, 10-100 of spreading hedyotis herbs, 10-100 of agrimonies, 10-100 of kudzuvine roots and the like. The invention further provides a plurality of methods of alcohol extraction, water extraction and alcohol precipitation, raw powder medicining and the like for preparing the bitter glossy ganoderma. The glossy ganoderma composition has anti-cancer, anti-tumor, anti-inflammatory, heat-clearing and detoxicating effects; and according to clinical and pharmacological pesticide effects and experiments, inhibition ratios of the glossy ganoderma composition on s180 sarcomas, H22 tumors and EL_4 lymphomas are 48.9%, 58.5% and 51.9% respectively, and an anti-inflammatory ratio of the glossy ganoderma composition is 65.0%.

Description

technical field [0001] The invention relates to the field of malignant tumor treatment, in particular to a bitter ganoderma composition for tumor treatment and a preparation method thereof. Background technique [0002] Cancer is a disease that seriously threatens human life and health. Chemotherapy drugs, while acting on tumor cells, can also significantly inhibit the growth or kill normal human cells, especially fast-growing cells, resulting in extremely toxic side effects on the human body. . Therefore, finding new drugs with strong anti-tumor effect and safety has become a topic of concern all over the world. Plant-derived antitumor drugs are diverse in their chemical structures and also in their mechanisms of action. Therefore, finding anti-tumor active substances that act on various targets from plants has great potential, and finding this type of botanical drugs has become a hot spot in the research of anti-tumor drugs. Contents of the invention [0003] The inve...

Claims

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Application Information

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IPC IPC(8): A61K36/748A61P35/00
Inventor 谢瑜谢世发王薪川
Owner 朱卫
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