High-field asymmetric waveform ion mobility spectrometry (FAIMS) based on ion wind pumping systems

Abstract

The invention discloses a FAIMS based on ion wind pumps, which comprises an electrical system and an ion mobility tube, wherein the ion mobility tube comprises an ion source, a separation detection system and an ion wind pumping system; a tube body of the ion mobility tube is composed of two substrates which are plated with electrodes and connected tightly with supporting beams to form air flow channels, and the electrodes comprise separation electrodes, detection electrodes, discharge electrodes and traction electrodes; wherein the separation electrodes, the detection electrodes and airflow channels among the separation electrodes and the detection electrodes form the separation detection system, the discharge electrodes, and the traction electrodes and airflow channels among the discharge electrodes and the traction electrodes form the ion wind pumping system; and the ion source is arranged on the inner side of an air inlet end of the substrate. A gaseous sample enters the ion mobility tube under the drive of the ion wind and is separated and detected by the separation detection system after being ionized by the ion source. According to the FAIMS based on ion wind pumping systems, monolithic integration can be achieved, the FAIMS based on ion wind pumping systems has the advantages of being high in integration, having no movable parts, and being simple in structure and easy to control, and highly integrated and stable FAIMS detections can be achieved.

Description

[0001] technical field [0002] The invention relates to the field of on-site analysis and detection instruments, in particular to a high-field asymmetric waveform ion mobility spectrometer. [0003] Background technique [0004] High-Field Asymmetry Ion Mobility Spectrometry (FAIMS) is a new type of ion mobility spectrometer. A high-low asymmetric waveform high-frequency electric field (high field>10000V / cm, frequency 0.5MHz~20MHz, high field duty ratio<0.5) is added to the longitudinal direction of the ion forward direction, and the longitudinal migration behavior of different material ions under this electric field is used. separate them by difference. Compared with conventional ion mobility spectrometers, high-field asymmetric waveform ion mobility spectrometers have the following advantages. First, the core component ion transfer tube is small in size and can be miniaturized; second, the ion loss is small, resulting in higher sensitivity; Third, the separation ...

AI Technical Summary

Problems solved by technology

[0008] Aiming at the defects of the existing high-field asymmetric waveform ion mobility spectrometer (FAIMS) based on an air pump, which has large volume, large interference, and low integration, the present invention discloses a high-field asymmetric waveform ion mobility spectrometer based on an ion wind pumping system, To meet the highly integrated needs of FAIMS on-site detection and the high stability of FAIMS

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