Application of bauhinia championii general flavone to preparation of medicament for treating rheumatoid arthritis

A rheumatoid, total flavonoid technology, applied in the directions of drug combination, antipyretic, anti-inflammatory agent, etc., to achieve the effects of clear efficacy, controllable quality and stable preparation method

Active Publication Date: 2012-07-18
广州高泰生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For the use of total flavonoids of Astragalus chinensis, there is no relevant literature report at present

Method used

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  • Application of bauhinia championii general flavone to preparation of medicament for treating rheumatoid arthritis
  • Application of bauhinia championii general flavone to preparation of medicament for treating rheumatoid arthritis
  • Application of bauhinia championii general flavone to preparation of medicament for treating rheumatoid arthritis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] The extraction of the total flavonoids of the vine of embodiment 1

[0019] 1.1 Reflux extraction method Weigh 20g of asparagus coarse powder, add 200ml of 70% ethanol to soak for 30min, then heat and reflux on a water bath to extract twice. Each time for 1h, filter while hot, and wash the residue with the corresponding solvent for 2-3 times , the combined filtrate was recovered until there was no alcohol smell, dissolved in water to contain 0.5g crude drug per 1mL, centrifuged (4000r / min) for 15min, filtered, and set aside. Take 1.0mL and put it in a 25mL measuring bottle, add 6.0mL of water; add 1.0mL of 5% (mass fraction) sodium nitrite solution, mix well, and let stand for 6min; add 10% (mass fraction) aluminum nitrate 1.0mL, shake Mix well and let stand for 6 minutes; then add 10.0 mL of 4% (mass fraction) NaOH solution, add water to the mark, shake well, let stand for 15 minutes; measure the absorbance A at a wavelength of 500 nm according to spectrophotometry (Ap...

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Abstract

The invention provides an application of a bauhinia championii general flavone to the preparation of a medicament for treating rheumatoid arthritis. The invention further provides a medicinal composition for treating rheumatoid arthritis. The bauhinia championii general flavone provided by the invention is used for treating rheumatoid arthritis, and has a definite curative effect and controllable quality; a preparation method of the medicinal composition is stable, and is suitable for mass production; and a novel option is provided for clinic treatment.

Description

technical field [0001] The present invention relates to a new application of total flavonoids of Ascaria sinensis. It belongs to the field of medicine. Background technique [0002] Longxuteng is the vine of Bauhinia championii Benth., also known as Jiulongteng and Meihuarugudan. It is mainly distributed in Fujian, Jiangxi, Guangxi, Zhejiang, etc., and has the effect of dispelling rheumatism and promoting blood qi. Modern pharmacological studies have proved that the active ingredients of Astragalus chinensis have the functions of expelling wind and dampness, promoting blood circulation and relieving pain, invigorating spleen and regulating qi, and are used to treat rheumatoid arthritis, waist and leg pain, bruises, stomach pain, and malnutrition in children. According to the prescription of Huang Jingang, a well-known doctor in southern Fujian, Kangmeifu Burn Ointment with Longxuteng as the main ingredient has a good clinical effect on treating burns and scalds. The chemic...

Claims

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Application Information

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IPC IPC(8): A61K36/48A61P19/02A61P29/00
Inventor 徐伟陈立典褚克丹李煌郑海音张玉琴
Owner 广州高泰生物科技有限公司
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