Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Production process of secoisolariciresinol diglucoside

A technology of flax lignans and production process, which is applied in the field of phytochemistry, and can solve the problems that cannot be directly applied to the column for adsorption

Inactive Publication Date: 2012-07-11
西安天一生物技术股份有限公司
View PDF7 Cites 10 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] ①Traditional crafts generally use linseed, less directly use pressed linseed oil residue
[0011] ③ Generally, a sedimentation step is required, and it cannot be directly adsorbed on the column

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Production process of secoisolariciresinol diglucoside
  • Production process of secoisolariciresinol diglucoside

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0042] ①Crush flaxseed dregs, pass through a 100-mesh sieve, add 5 times the amount of 70% ethanol and 0.015 times the amount of 98% sodium hydroxide to the oil residue, and extract under reflux for 2 hours at a temperature of 80°C, and filter the extract with a suction filter bottle .

[0043] ② Concentrate the alkali-alcohol extract obtained in ① to a specific gravity of 1.05-1.1 and adjust the pH to 6.5 with acetic acid.

[0044] ③Put the concentrated solution adjusted in ② directly on the macroporous adsorption resin D101, wash the resin with purified water at 10°C, then elute with 20-50% ethanol, concentrate the eluent, and spray dry to obtain 40-60% flax Lignans.

[0045] ④ Dissolve the crude flax lignans obtained in ③ with 5 times the amount of acetone and stir for 1 hour, filter with suction, concentrate the filtrate, and spray dry to obtain 98% flax lignans.

Embodiment 2

[0047] ① Grind linseed medicinal residues, pass through a 20-mesh sieve, add 20 times the amount of 99.9% ethanol and 0.02 times the amount of 95% sodium hydroxide to the oil residues, and extract under reflux for 4 hours at a temperature of 70°C, and filter the extract with a suction filter bottle .

[0048] ② Concentrate the alkali-alcohol extract obtained in ① to a specific gravity of 1.05-1.1 and adjust the pH to 7 with hydrochloric acid.

[0049] ③Put the concentrated solution adjusted in ② directly on the macroporous adsorption resin AB-8, wash the resin with purified water at 5°C, then elute with 20-50% ethanol, concentrate the eluent, and spray dry to obtain 40-60% of flax lignans.

[0050] ④ Dissolve the crude flax lignans obtained in ③ with 5 times the amount of n-butanol and stir for 1 hour, filter with suction, concentrate the filtrate, and spray dry to obtain ≥97.3% flax lignans.

Embodiment 3

[0052] ①Crush the linseed medicinal residue, pass through a 40-mesh sieve, add 20 times the amount of 80% ethanol and 0.03 times the amount of 95% sodium hydroxide to the oil residue, and extract under reflux for 3 hours at a temperature of 80°C, and filter the extract with a suction filter bottle .

[0053] ② Concentrate the alkali-alcohol extract obtained in ① to a specific gravity of 1.05-1.1 and adjust the pH to 7 with sulfuric acid.

[0054] ③Put the concentrated solution adjusted in ② directly on the macroporous adsorption resin DM130, wash the resin with purified water at 20°C, then elute with 20-50% ethanol, concentrate the eluent, and spray dry to obtain 40-60% flax Lignans.

[0055] ④ Dissolve the crude flax lignans obtained in ③ with 5 times the amount of ethyl acetate and stir for 1 hour, filter with suction, concentrate the filtrate, and spray dry to obtain ≥98.6% flax lignans.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a production process of secoisolariciresinol diglucoside and the production process is characterized by comprising the following steps of: extracting secoisolariciresinol diglucoside from linseed oil residue, and performing extraction, concentration and acidity adjustment, loading on a column, drying and refining, so as to obtain secoisolariciresinol diglucoside with concentration being not less than 95%. The product is stable in properties and can be applied to the fields such as healthcare foods, medicines, healthcare products and drinks. According to the process, the linseed oil residue after oil is squeezed can be directly used, and the steps of extracting and then hydrolyzing, as well as concentrating and then adjusting pH value are avoided. The filtrate is directly load on the column without the need of sedimentation after concentration and pH value adjustment are performed; and the process is simple and practicable.

Description

technical field [0001] The invention relates to a plant extract, in particular to a production process of flax lignans, belonging to the technical field of phytochemistry. Background technique [0002] Flax (Linum usitatissimum L.), also known as flax, belongs to the family Linaceae and is one of the oldest crops. Flaxseed, also known as flaxseed, is an important economic oil crop, which is widely planted in Gansu, Shaanxi, Shanxi and other places in my country. Especially in Gansu, the output is large and the quality is good. The content of flax pignin in the raw material is as high as 1.8%-4%, which has high development and utilization value. [0003] Flax lignans are an active ingredient in flaxseeds, which exist in the form of chelation in plants, and can be hydrolyzed and extracted with fat-soluble solvents to obtain free flax lignans. [0004] The structure of flax lignans is very similar to the female structure of the human body. Flax lignans extracted from plants a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C07H15/18C07H1/00C07H1/08
Inventor 李凡叶涛田艳娜
Owner 西安天一生物技术股份有限公司
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com