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Pharmaceutical composition for treating ischemic cerebrovascular diseases and preparation method and applications thereof

A cerebrovascular disease and composition technology, applied in the field of pharmaceutical compositions for the treatment of ischemic cerebrovascular disease, can solve problems such as increasing the medical burden of patients, and achieve the effects of treating and preventing cerebral thrombosis, reducing volume, and reducing thrombosis

Inactive Publication Date: 2013-11-20
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

These traditional Chinese medicine compounds have greatly increased the medical burden of patients

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The preparation of embodiment 1 pharmaceutical composition of the present invention

[0025] Take astragalus 30g, ginseng 12g, angelica 12g, chuanxiong 12g, blood-sucking leech 6g, white peony root 15g, Cyperus cyperi 12g, and Achyranthes bidentata 20g. Weigh each herbal flavor according to the amount, decoct in strong fire and water, after boiling, change to simmer and decoct for 30 minutes to get it.

Embodiment 2

[0026] The preparation of embodiment 2 pharmaceutical composition of the present invention

[0027] Astragalus 21g, ginseng 15.6g, angelica 15.6g, Chuanxiong 15.6g, blood-sucking leech 7.8g, white peony root 19.5g, Cyperus cyperi 15.6g, Achyranthes bidentata 26g, add water and boil 3 times, each time use 6-10g of the weight of the material Double the water, decoct for 15-30 minutes each time, and combine the decoction; then take 3g of blood-sucking leech, crush it, add it to the medicinal liquid and stir well, and you get it.

Embodiment 3

[0028] The preparation of embodiment 3 pharmaceutical composition of the present invention

[0029] Astragalus 36g, Ginseng 8.4g, Angelica 8.4g, Chuanxiong 8.4g, Leech 4.2g, Paeoniae Alba 10.5g, Cyperus cyperi 8.4g, Achyranthes bidentata 14g, add water to decoct twice, each time use 8-12 times the weight of the material , decocting for 20-40 minutes each time, combining the decoction, concentrating, adding dextrin and soluble starch, wet granulation, and drying to obtain.

[0030] The beneficial effects of the present invention will be specifically described below through test examples.

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Abstract

The invention discloses a pharmaceutical composition for treating ischemic cerebrovascular diseases, which relates to a preparation prepared from the following crude drugs in proportioning by weight: 21-36 parts of Astragalus mongholicus, 8.4-15.6 parts of ginseng, 8.4-15.6 parts of Angelica sinensis, 8.4-15.6 parts of Ligusticum wallichii, 4.2-7.8 parts of leech, 10.5-19.5 parts of radix paeoniae alba, 8.4-15.6 parts of rhizoma cyperi and 14.26 parts of twotooth achyranthes. The invention also discloses a preparation method for the pharmaceutical composition and applications of the pharmaceutical composition. According to the pharmaceutical composition disclosed by the invention, thrombopoiesis can be reduced; the brain infarct volume can be reduced; and the ischemic cerebrovascular diseases can be effectively treated and prevented, such as cerebral thrombosis, cerebral embolism, cerebral apoplexy and the like; and a new selection is provided for clinical medication.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating ischemic cerebrovascular disease, its preparation method and application. Background technique [0002] Ischemic cerebrovascular disease is a multiple disease that causes focal damage due to blood supply disturbance to the brain, including transient ischemic attack (TIA), cerebral thrombosis, cerebral embolism, and cerebral apoplexy. Western medicine has no specific medicine for ischemic cerebrovascular disease, and its treatment is mainly to control diet and strengthen physical exercise, supplemented by drug treatment. Its drug treatment mainly adopts dilating blood vessels (using Naoyizine, Nimodipine, Flunarizine and other calcium ion antagonists) and reducing blood lipid concentration (using Niacinate Inositol Lipid, Duoxekang, Zhibituo, and noninositol). Norbert, etc.) and other measures are sometimes supplemented with activation of nerve cells (with gamma-amino acid, brain fuxin,...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8905A61P7/02A61P9/10A61K35/62
Inventor 李戎梁繁荣
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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