Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Water-soluble cyclized metal iridium complex with sugary ligand and application of complex

A technology of iridium complexes and complexes, which is applied in the direction of sugar derivatives, chemiluminescence/bioluminescence, and analysis by making materials undergo chemical reactions, can solve the problems of insoluble metal iridium luminescent probes in aqueous solution, and achieve luminescence quantum The effect of high yield

Inactive Publication Date: 2012-06-20
FUZHOU UNIV
View PDF1 Cites 8 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The luminescent probe of the cyclized metal iridium complex synthesized by the invention can be dissolved in water, which solves the problem that the metal iridium luminescent probe is insoluble in aqueous solution, and can be applied to the analysis test in aqueous solution

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Water-soluble cyclized metal iridium complex with sugary ligand and application of complex
  • Water-soluble cyclized metal iridium complex with sugary ligand and application of complex
  • Water-soluble cyclized metal iridium complex with sugary ligand and application of complex

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Synthesis of sugar-containing ligand I: 0.75 g of 1-thio-β-D-glucose tetraacetate and 0.71 g of sodium carbonate were added to 0.32 g of 4,4'-dibromomethyl-2,2'-linked pyridine in DMF solution, stirred at room temperature for two days and 48 hours, spin-dried, added about 20 ml of water to dissolve, the mixture was extracted three times with ethyl acetate, the organic layer was retained, dried with sodium sulfate, and purified by column chromatography (ethyl acetate / n-hexane). , volume ratio=3:1) to obtain a white solid; dissolve the white solid in about 20 ml of methanol, add 150 mg of sodium methoxide, stir at room temperature for 12 hours, filter, precipitate and wash with methanol, and dry to obtain a white powder (yield 84%) ), which is sugar-containing ligand I.

Embodiment 2

[0032] The process or method of using the product:

[0033] (1) Metal iridium complex [(ppy) 2 Ir(I)]Cl, [(pq) 2 Ir(I)]Cl and [(pzq) 2 Detection of tripropylamine in Ir(I)]Cl aqueous solution: prepare 0.05mmol / L iridium(III) complex with 50mmol / L phosphate buffer solution (pH=7.5), use Ag / AgCl electrode as reference electrode, Pt wire As the counter electrode, a Pt disk (2 mm in diameter, Shanghai Chenhua) was used as the working electrode, and the cyclic voltammogram was scanned in the range of 0-1.4 V to obtain the corresponding electrochemiluminescence signal. Adding the same concentration of tripropylamine to various metal iridium complex solutions, the electrochemiluminescence of the system is greatly enhanced. Under the same conditions, [(pq) 2 Ir(I)]Cl has the strongest electrochemiluminescence, followed by [(bzq) 2 Ir(I)]Cl and [(ppy) 2 Ir(I)]Cl as figure 1 . Based on the relationship between the electrochemiluminescence intensity and the concentration of ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention provides a water-soluble cyclized metal iridium complex with a sugary ligand and application of the complex, wherein the cyclized metal iridium complex is generated by means of reaction between the sugary ligand and a chlorendic dikaryon iridium complex, can serve as an electrochemical luminescence and photoluminescence probe and is applied to detecting amine drugs in an aqueous solution system or used for biological markers. The cyclized metal iridium complex serving as the luminous probe is water-soluble and high in luminous quantum yield, solves the problem of a metal iridium luminous probe is insoluble in aqueous solution, and can be applied to analysis and test in aqueous solution.

Description

technical field [0001] The invention relates to the fields of electrochemiluminescent materials and biological analysis, and more specifically relates to a water-soluble cyclized metal iridium complex containing sugar ligands and applications thereof. Background technique [0002] The currently published luminescent probes of cyclic metal iridium complexes mainly include neutral complexes and cationic complexes. Polycyclic metal ligands contain a neutral coordinating moiety and an anionic moiety. The neutral coordination moiety usually contains N^N neutral bidentate ligands (such as bipyridyl or o-phenanthroline derivatives). The anion part is a C^N-containing ligand such as phenylpyridine (ppy), in which the phenyl ring acts as the anion part, and the Ir-C bond formed between the metal Ir(III) and the ppy ligand is very strong, comparable to a covalent bond . Therefore, the iridium complex has good thermal stability and extensive electronic interactions between the d or...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C07H15/26C07H23/00C09K11/06G01N21/76G01N21/64
Inventor 李梅金焦鹏冲林敏何伟文吴昭珍陈曦
Owner FUZHOU UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com