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Chinese herbal compound, as well as preparation method and application thereof

A technology of compound preparations and traditional Chinese medicines, applied in the directions of medical formulas, antipyretics, drug combinations, etc., can solve the problems of not being able to cope with the treatment needs of clinical critically ill patients with influenza

Inactive Publication Date: 2012-05-30
SHANGHAI SHYNDEC PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Since influenza virus vaccines and existing antiviral drugs cannot cope with the variation of influenza and the treatment needs of clinical critically ill patients, it is urgent to find new anti-influenza drugs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1: the preparation of the active component of medicine of the present invention

[0029] (1) Weigh the raw materials of traditional Chinese medicine according to the following weight ratio (taking 10 times the ratio of raw materials as an example): 120 parts of Notopterygium, 60 parts of Angelica dahurica, 180 parts of Folium Folium, 180 parts of Scutellaria baicalensis, 60 parts of Sophora flavescens, and Fructus Cnidii 60 servings.

[0030] (2) Weigh notopterygium, Angelica dahurica, Folium Folium, Scutellaria baicalensis, Sophora flavescens, Cnidium chinensis in the above weight ratio, add 10 times the amount of water to decoct for 1 hour, filter; add 8 times the amount of water to decoct for 1 hour, filter the residue . Combine the filtrates, concentrate to a relative density of 1.25, add 95% ethanol to make the solution alcohol content 70%, and ethanol precipitation for 24 hours. The ethanol is recovered and concentrated to an extract with a specific g...

Embodiment 2

[0031] Embodiment 2: the preparation of the active component of medicine of the present invention

[0032] (1) Weigh the raw materials of traditional Chinese medicine according to the following weight ratio (take 10 times the ratio of raw materials as an example): 100 parts of Notopterygium, 50 parts of Angelica dahurica, 150 parts of Daqing Ye, 150 parts of Scutellaria baicalensis, 50 parts of Sophora flavescens, Cnidium chinensis 50 servings.

[0033] (2) Take notopterygium, Angelica dahurica, Folium Folium, Scutellaria baicalensis, Sophora flavescens, Fructus Cnidii by weighing the above-mentioned weight proportions, and the preparation steps are the same as in Example 1 to prepare extracts and obtain the active components of the medicine of the invention.

Embodiment 3

[0034] Embodiment 3: the preparation of the active component of medicine of the present invention

[0035] (1) Weigh the raw materials of traditional Chinese medicine according to the following weight ratio (taking 10 times the ratio of raw materials as an example): 400 parts of Notopterygium, 200 parts of Angelica dahurica, 500 parts of Daqing Ye, 500 parts of Scutellaria baicalensis, 200 parts of Sophora flavescens, Cnidium chinensis 200 copies.

[0036] (2) Take notopterygium, Angelica dahurica, Folium Folium, Scutellaria baicalensis, Sophora flavescens, Fructus Cnidii by weighing the above-mentioned weight proportions, and the preparation steps are the same as in Example 1 to prepare extracts and obtain the active components of the medicine of the invention.

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PUM

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Abstract

The invention belongs to the technical field of Chinese herbal compound preparations for preventing or treating cold. A Chinese herbal compound disclosed by the invention comprises the following Chinese medicine raw materials in parts by weight: 1-40 parts of incised notopterygium rhizome, 1-20 parts of dahurian angelica root, 1-50 parts of indigowoad leaves, 1-50 parts of baical skullcap root, 1-30 parts of lightyellow sophora root and 1-30 parts of common cnidium fruit. The Chinese herbal compound preparation disclosed by the invention integrates the effects of dispelling exopathogens with pungent, relieving the exterior syndrome with drugs pungent in flavor and cool in property and clearing fever and detoxicating into a whole, is different from a single exterior-resolving or fever-clearing agent in the past, advocates defending the exterior by firstly sweating and expelling pathogenic factors and combining cold with warm, is good in defervescence effect and has significant clinical effects when being clinically used for treating symptoms of influenza and common cold, including symptoms, such as fever or high fever, aversion to cold, muscular soreness, nasal congestion, runny nose, sore throat, itchy throat, red tongue with thin and white or thin and yellow fur and the like.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine compound preparations for preventing or treating influenza and common cold. Background technique [0002] Clinically, colds are divided into two categories: influenza and common cold. [0003] Influenza (flu for short) is an acute respiratory infection caused by influenza virus. The typical clinical symptoms are: sudden onset of high fever, general pain, significant fatigue and mild respiratory symptoms. Influenza has always been one of the most frequent infectious diseases in the world, and about 10% of the world's population is infected with influenza every year. In the 20th century alone, three worldwide influenza pandemics broke out, causing hundreds of millions of people to be infected. The 2009 Influenza A (H1N1) global pandemic once again aroused the attention of various countries to influenza. [0004] The main measure to prevent influenza is vaccination. However, ...

Claims

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Application Information

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IPC IPC(8): A61K36/539A61P11/00A61P29/00A61P31/16
Inventor 颜德馨颜乾麟
Owner SHANGHAI SHYNDEC PHARMA CO LTD
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