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Preparation method of traditional Chinese medicine preparation Jinshuibaojin oral liquid

The technology of Jinshuibaojin oral liquid and oral liquid, which is applied in the field of oral liquid, can solve the problems of unfavorable drug dissolution and absorption, 15-20 minutes, and long disintegration time, and achieve the advantages of dissolution and absorption, good taste, The effect of high content of active ingredients

Inactive Publication Date: 2012-05-02
JIANGXI JEMINCARE GRP CO LTD +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The usage and dosage are oral, 6 capsules at a time, twice a day; however, Jinshuibao Gold Capsules are ordinary capsules, made into capsules, and the disintegration time limit is 30 minutes, usually 15-20 minutes. Long, it is not conducive to the dissolution and absorption of drugs, and the onset of effect is slow, which is also not conducive to the exertion of drug efficacy.

Method used

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  • Preparation method of traditional Chinese medicine preparation Jinshuibaojin oral liquid

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0021] Experimental example 1: the choice of flavoring agent

[0022] The oral liquid of the present invention contains fermented Cordyceps fungus powder and American ginseng. As an oral preparation, the mouthfeel is important, and flavoring agents must be added to be accepted by people who need to take it. Commonly used flavoring agents in oral liquids include sucrose, honey, starch syrup, protein sugar, etc. At present, sucrose is the commonly used flavoring agent, because sucrose is sweet in taste and cold in nature, it has the effects of moistening lungs and promoting body fluid, harmonizing lungs, and soothing liver qi. Efficacy, according to the above situation, select sucrose to prepare as flavoring agent.

experiment example 2

[0023] Experimental example 2: Selection of extraction method

[0024] method one,

[0025] Take 400g of fermented Cordyceps powder, 400g of American ginseng, add 6 times the amount of water and decoct twice, the first time for 2 hours, the second time for 2 hours, combine the decoction liquid and filter, the filtrate is concentrated to a specific gravity of 1.1 (80°C), and let it cool Add 80% ethanol to the final clear ointment, stir well to make the alcohol content reach 60%, let it stand for 48 hours, take the alcohol precipitation supernatant and heat to recover the ethanol until there is no alcohol smell, concentrate until the specific gravity is 1.30 (60°C), add 8 times the amount of water and 3g of sodium benzoate, stir well, let stand for 48 hours, take the supernatant and filter it with a stainless steel plate frame machine, add honey 150g, ethylparaben 0.3g to the filtrate (use 4 times the amount of 95% Dissolved in ethanol), heated and boiled for 30 minutes, allowe...

Embodiment 4

[0043] Embodiment 4: oral liquid of the present invention

[0044] Fermented Cordyceps Powder 400g

[0045] American ginseng 400g

[0046] Sucrose 150g

[0047] Sodium Benzoate 3g

[0048] Ethylparaben 0.3g

[0049] 95% ethanol 1.2g

[0050] Above-mentioned raw material is mixed with oral liquid 1000ml as follows;

[0051] Take 400g of fermented Cordyceps powder, 400g of American ginseng, add 6 times the amount of water and decoct twice, the first time for 2 hours, the second time for 2 hours, combine the decoction liquid and filter, the filtrate is concentrated to a specific gravity of 1.1 (80°C), and let it cool Add 80% ethanol to the final clear ointment, stir well to make the alcohol content reach 60%, let it stand for 48 hours, take the alcohol precipitation supernatant and heat to recover the ethanol until there is no alcohol smell, concentrate until the specific gravity is 1.30 (60°C), add 8 times the amount of water and 3g of sodium benzoate, stir well, let stand...

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Abstract

The invention belongs to the pharmaceutical field, in particular relates to Jinshuibaojin oral liquid and a preparation method thereof. The oral liquid provided by the invention is prepared by the following raw materials in part by weight: 300-700 parts of fermented cordyceps fungus powder, 300-700 parts of ginseng, 130-170 parts of sucrose, 1-7 parts of sodium benzoate and 0.1-0.7 part of ethylparaben.

Description

technical field [0001] The invention relates to an oral liquid, in particular to a Jinshuibaojin oral liquid and a preparation method thereof. Background technique [0002] Jinshuibao Gold Capsule is a capsule made of fermented Cordyceps fungus powder and appropriate amount of excipients. It is recorded in the enterprise standard of Jiangxi Jiminxin Pharmaceutical Co., Ltd. The health function of physical fatigue is suitable for the crowd: those with low immunity, those in an oxygen-deficient environment, and those who are prone to fatigue. Dosage is oral, 6 capsules at a time, 2 times a day; however, Jinshuibao Gold Capsules are ordinary capsules, made into capsules, and the disintegration time limit is 30 minutes. Generally, it takes 15-20 minutes. Long, not conducive to the dissolution and absorption of drugs, slow onset of action, which is also not conducive to the performance of the drug. Contents of the invention [0003] The object of the present invention is to p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/258A61K9/08A61P37/04A61P39/00
Inventor 彭启华邹武斌
Owner JIANGXI JEMINCARE GRP CO LTD
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