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Chinese medicine extract composition with whitening skin care function and application of Chinese medicine extract composition

An extract and composition technology, applied in the field of compound traditional Chinese medicine compositions, can solve the problems of instability of vitamin C and SOD, single action of arbutin, large irritation of hydroquinone, etc. Whitening effect, less skin irritation effect

Inactive Publication Date: 2012-04-11
GUANGDONG IND TECHN COLLEGE +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But there are many defects in these whitening agents, such as hydroquinone is very irritating, vitamin C and SOD are very unstable, kojic acid also has certain irritation and easy discoloration, arbutin has a single effect and poor effect, etc.

Method used

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  • Chinese medicine extract composition with whitening skin care function and application of Chinese medicine extract composition
  • Chinese medicine extract composition with whitening skin care function and application of Chinese medicine extract composition
  • Chinese medicine extract composition with whitening skin care function and application of Chinese medicine extract composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Example 1 Experimental method and results of whitening skin care effect evaluation

[0019] 1. Preparation of sample

[0020] The above-mentioned traditional Chinese medicine extract composition was dissolved in dimethyl sulfoxide to prepare a sample solution with a concentration of 0.1%, and the following experiment was performed. At the same time, arbutin was used as a control sample.

[0021] 2. Evaluation test of the effect of inhibiting tyrosinase activity

[0022] Accurately draw the sample solution, phosphate buffer solution (PBS) with pH 6.8 and Dopa solution with a mass fraction of 0.1% according to Table 2, mix them thoroughly, incubate at 30°C for 5 minutes, and add phenol with an activity of 110 U / mL The amino acid enzyme solution was incubated at 30°C for 10 minutes, and then quickly transferred to a cuvette, and the absorbance was measured at 475nm. Kojic acid, hydroquinone, ascorbic acid, and arbutin were used as controls.

[0023] Table 2

[0024]

[0025] Calcu...

Embodiment 2

[0046] Example 2 Chinese medicine extract composition

[0047] The traditional Chinese medicine extract composition (I) with whitening and skin care functions is composed as follows in weight percentage:

[0048]

[0049]

[0050] The Chinese medicine extract composition (II) with whitening and skin care functions is composed as follows in weight percentage:

[0051]

[0052] The Chinese medicine extract composition (III) with whitening and skin care functions is composed as follows in weight percentage:

[0053]

Embodiment 3

[0054] Example 3 Preparation of whitening skin care lotion

[0055] Table 5 shows the whitening skin care milk formula containing the Chinese medicine extract composition, and the dosage of each substance is expressed by mass fraction.

[0056] table 5

[0057]

[0058] The preparation method of whitening skin care lotion: add dimethyl siloxane, isopropyl palmitate, glyceryl caprylate, monoglyceride, stearic acid, methyl paraben, propyl paraben in the formula table Mix, heat to 80°C, melt and stir evenly, as the oil phase; mix 1,2-propanediol, Chinese medicine extract composition, triethanolamine, and deionized water in the formula table, heat to 85°C, stir and dissolve evenly, as water box. Add the oil phase and the water phase to the emulsifying pot, stir evenly, emulsify and homogenize for 6 minutes, stir and cool to 50°C, add the essence, stir evenly, and cool to 38°C, which is the whitening skin care lotion.

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PUM

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Abstract

The invention discloses a Chinese medicine extract composition with a whitening skin care function and application of the Chinese medicine extract composition. The medicine extract composition is prepared by compounding a grape seed extract, a shatian pomelo seed extract, a glycyrrhiza glabra extract, a white muscardine silkworm extract, a Szechuan lovage rhizome extract, a litchi pericarp extract, a spina date seed extract and a chickpea extract. The Chinese medicine extract composition can be used for whitening skin care cosmetics, can effectively inhibit tyrosinase activity and melanin synthesis, has effects of eliminating free radicals and resisting ultraviolet rays, and is a safe and high-efficiency whitening skin care agent.

Description

Technical field [0001] The invention relates to a compound Chinese medicine composition, which has skin whitening and care functions and can be applied to skin whitening and skin care cosmetics. Background technique [0002] Skin whitening and care is the theme of cosmetics, and cosmetics with skin whitening and skin care functions are one of the best-selling cosmetics. Modern scientific research has proved that skin aging is a very complex process, which is affected by many factors, among which the production of melanin and the degeneration of skin elastic fibers caused by free radicals are the two main factors. The formation process of melanin is: tyrosine in the melanocytes of human skin is oxidized to dopa and dopaquinone under the catalysis of tyrosinase, which are further oxidized after rearrangement Dopachrome, 5,6-dihydroxyindole (5,6-dihydroxyindole), indole-5,6-quinone, and finally synthesis of melanin (melanin), the reaction is figure 1 Shown. [0003] The main factor...

Claims

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Application Information

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IPC IPC(8): A61K8/99A61K8/97A61Q19/02
Inventor 龚盛昭
Owner GUANGDONG IND TECHN COLLEGE
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