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Experimental animal sign information collection and analysis system and collection and analysis method

A technology for collecting and analyzing animals, used in image analysis, medical science, image data processing, etc., it can solve problems such as difficulty in implementing diagnostic methods, achieve objectivity and accuracy, reduce human errors, and solve image distortion. Effect

Inactive Publication Date: 2012-03-28
GUANGXI UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

TCM itself is summed up through the experience of clinical practice. "Looking, smelling, asking, and feeling" is an important basis for TCM syndrome differentiation and diagnosis. ", cut" diagnostic method is difficult to implement in experimental animals

Method used

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  • Experimental animal sign information collection and analysis system and collection and analysis method
  • Experimental animal sign information collection and analysis system and collection and analysis method
  • Experimental animal sign information collection and analysis system and collection and analysis method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Example 1: Collection and Analysis of Rat Tongue Color

[0015] ①Turn on the power of the system; ②Turn on each instrument, start the rat sign collection and analysis system software; ③Photometer, calibrate the ruler and standard color card, and correct the instrument and system; ④Turn on the tongue image dynamic observation and collection module; ⑤Anesthetize the rat Finally, pull out the rat’s tongue with non-invasive tweezers, observe and take pictures of the front and back sides of the tongue; ⑥ save the image; Draw a line, the software will automatically cut out the tongue part to be analyzed, and delete the background), and then remove the background (use the mouse to draw a line on the wrongly selected part of the image by the computer, and the computer will automatically delete the redundant background part by mistake), After you are satisfied, click the "Finish" button, the system will automatically analyze the displayed data, and export the analysis results of...

Embodiment 2

[0016] Example 2: Collection and Analysis of Rat Tail Congestion Ratio

[0017] ①Turn on the power of the system; ②Turn on each instrument, start the rat sign collection and analysis system software; ③Photometry, calibrate the ruler and standard color card, correct the instrument and system; ④Turn on the rat tail collection and analysis module; ⑤After anesthetizing the rat , straighten the tail of the rat, and take a tail image; ⑥ save the image; ⑦ start the analysis module, load the image, click the "two-point method" button, and first measure the length of the tail blood stasis (use the mouse to place the starting point of the tail blood stasis position and Click each end point, the software will automatically measure the actual length of the blood stasis site, and display the result), then measure the total length of the tail (the method is the same as before), click the "Finish" button, the system will automatically analyze and display the data, and the large The analysis ...

Embodiment 3

[0018] Example 3: Color collection and analysis of rat paws

[0019] ①Turn on the power of the system; ②Turn on each instrument, start the rat sign collection and analysis system software; ③Photometer, calibrate the ruler and standard color card, correct the instrument and system; ④Open the paw dynamic observation and collection module; ⑤Anesthetize the rat Finally, make the rat in a supine position, observe and take images of the four paws of the rat; ⑥ save the image; ⑦ start the analysis module, load the image, click the "cutout analysis" button, and first select the foreground (draw on the tongue with the mouse). One line, the software will automatically cut out the tongue part to be analyzed and delete the background), and then remove the background (use the mouse to draw a line on the wrongly selected part of the image by the computer, and the computer will automatically delete the wrongly selected redundant background part), satisfied Finally, click the "Finish" button,...

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Abstract

The invention relates to an experimental animal sign information acquisition and analysis system and a collection and analysis method thereof, which are characterized by comprising a hardware system, a software system and an implementation method. The hardware system comprises a light source, a shading component, a digital camera, a stepper motor for controlling the digital camera to move, a connecting device and a computer. The software system comprises a digital camera moving and shooting control program, a database program, and an image analysis program. The implementation method is that: experimenters operate the system to complete the collection and analysis of data according to instructions. The image analysis program also comprises a tongue image automatic collection and analysis module, a whole hair color collection and analysis module, an ear collection and analysis module, a claw collection and analysis module, and a tail collection and analysis module. The analysis method comprises the following steps of automatic image storage, smart-cut of analysis target images, and automatic extraction and storage of sign data. The system has a scientific design and high degree of automation, is convenient to use, and can be used for a collection and analysis research of various experimental animal sign images, and the obtained experimental data is objective, scientific, and reliable.

Description

Technical field: [0001] The invention relates to a system for collecting and analyzing image information of experimental animal signs, in particular to a combination design of a hardware system for digital image collection and a method for analyzing and processing images by a software system. Background technique: [0002] To realize the true integration of traditional Chinese medicine with modern science and technology, major basic research such as the replication of animal models of TCM syndromes is essential, but animal models of TCM syndromes are different from pathological models of Western medicine, and the simulation from etiology to syndromes should conform Theory of Traditional Chinese Medicine. TCM itself is summed up through the experience of clinical practice. "Looking, smelling, asking, and feeling" is an important basis for TCM syndrome differentiation and diagnosis. , cut" diagnostic method is difficult to implement in experimental animals. Therefore, it is ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/00G06T7/00
Inventor 邓家刚杜正彩郝二伟
Owner GUANGXI UNIV OF CHINESE MEDICINE
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