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Eyedrops for treating presbyopia and preparation method thereof

A technology of eye drops and water for injection, which is applied in medical formulas, medical preparations containing active ingredients, drug combinations, etc., can solve the problems of lack of eye drops for treating presbyopia, etc., and achieve non-toxic side effects, stable drug effects, and quick results Effect

Active Publication Date: 2012-03-14
于 强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Clinically, there are treatments for glaucoma, cataract, etc., but there is still a lack of eye drops or similar products for the treatment of presbyopia

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] Get the purchased raw materials and grind them into powder, and weigh them according to 10 grams of xuanming powder, 20 grams of borax, 15 grams of mirabilite, 25 grams of calamine, and 40 grams of borneol.

[0031] Mix Xuanming powder, borax and Glauber's salt, add 180ml of water for injection, stir and dissolve at 80°C for 45 minutes. Add calamine to 180 ml of 0.1 mol / l boric acid solution (wherein the solvent is water for injection), heat and stir at 80° C. for 45 minutes. The borneol was firstly mixed with Tween-80, then water for injection at 50°C was added, and heated and stirred at 80°C for 45 minutes. Mix the supernatant after heating and dissolving the above raw materials, adjust the pH value to 7.4 with 0.1mol / l boric acid solution, add water for injection to 1000ml, add sodium chloride to adjust the osmotic pressure, so that the eye drops are equivalent to 0.9% sodium chloride Concentration, finely filtered until clear, sterilized with circulating steam at 1...

Embodiment 2

[0033] Get each raw material that buys and grind into powder, and according to 13 grams of Xuanming powder, 24 grams of borax, 17 grams of Glauber's salt, 30 grams of calamine, 16 grams of borneol are weighed for future use.

[0034] Mix Xuanming powder, borax and Glauber's salt, add 200ml of water for injection, stir and dissolve at 85°C for 30 minutes. Add calamine to 200ml of 0.1mol / l boric acid solution (wherein the solvent is water for injection), heat and stir at 85°C for 30 minutes. The borneol was firstly mixed with Tween-80, then water for injection at 50°C was added, and heated and stirred at 80°C for 30 minutes. Mix the supernatant after heating and dissolving the above raw materials, adjust the pH value to 7.4 with 0.1mol / l boric acid solution, add water for injection to 1000ml, add sodium chloride to adjust the osmotic pressure, so that the eye drops are equivalent to 1.0% sodium chloride Concentration, finely filtered until clear, sterilized with circulating ste...

Embodiment 3

[0036] Get the purchased raw materials and grind them into powder, and weigh them according to 15 grams of Xuanming powder, 27 grams of borax, 20 grams of mirabilite, 10 grams of calamine, and 22 grams of borneol.

[0037]Mix Xuanming powder, borax and Glauber's salt, add 180ml of water for injection, stir and dissolve at 85°C for 35 minutes. Add calamine to 180 ml of 0.1 mol / l boric acid solution (wherein the solvent is water for injection), and heat and stir at 85° C. for 35 minutes. The borneol was firstly mixed with Tween-80, then water for injection at 55°C was added, and heated and stirred at 85°C for 35 minutes. Mix the supernatant after heating and dissolving the above raw materials, adjust the pH value to 8.4 with 0.1mol / l boric acid solution, add water for injection to 1000ml, add sodium chloride to adjust the osmotic pressure, so that the eye drops are equivalent to 0.95% sodium chloride Concentration, finely filtered until clear, sterilized with circulating steam ...

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PUM

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Abstract

The invention relates to eyedrops for treating presbyopia, which comprise the following effective components proportioned according to parts by weight: 1 to 2 parts of natrii sulfas exsiccatus, 1.6 to 3 parts of borax, 1 to 2 parts of Glauber's salt, 1 to 3 parts of calcined calamine and 1.6 to 4 parts of borneol. The eyedrops for treating the presbyopia also contain an amount of water as a solvent. The invention also discloses a preparation method of the eyedrops. The eyedrops disclosed by the invention not only have an obvious curative effect on the presbyopia, but also have a good curativeeffect on dry eyes.

Description

technical field [0001] The invention relates to an eye drop, especially an eye drop for treating presbyopia. The invention also provides a preparation method of the eye drops. Background technique [0002] Presbyopia, also known as presbyopia, is a manifestation of the aging of the eyes of the elderly. Everyone knows that everyone has an aging process, such as the graying of the hair, loose skin, and muscle atrophy of the elderly. The adjustment function of the eyes will also age. With the increase of age, the elasticity of the lens gradually decreases, and the function of the ciliary body gradually weakens. When looking at nearby objects, the lens cannot become convex, and the image cannot be focused on the retina. Objects are very clear. When reading a book, you should hold the book farther away, or require sufficient light to see clearly. These conditions are presbyopia. [0003] The etiology and pathology of presbyopia: presbyopia is a natural physiological aging pheno...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/30A61P27/10A61K31/045A61K33/04A61K33/22
Inventor 于强
Owner 于 强
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