Method for synthesizing L-ascorbyl palmitate

Abstract

The invention discloses a method for synthesizing L-ascorbyl palmitate, which comprises the following steps: grinding L-ascorbyl palmitate into fine powder; at 25 to 20 DEG C, slowly adding the L-ascorbyl palmitate fine powder into pure sulfuric acid so that the L-ascorbyl palmitate fine powder dissolves in the sulfuric acid; adding L-ascorbyl palmitate in an amount which is 0.95 times the molar number of L-ascorbyl palmitate into the reaction solution, adding dehydrating agent into the reaction solution, and continuing reaction for 6 to 7 hours; pouring the generated reaction solution into broken ice, filtering out coarse product, drying and washing with water; heating the prepared coarse L-ascorbyl palmitate, dissolving the coarse L-ascorbyl palmitate in ethyl acetate, and decolorizing and purifying the solution by particle active carbon; and subjecting the obtained solution to reduced-pressure distillation and concentration, cooling feed liquid to 0 DEG C and discharging to obtain L-ascorbyl palmitate white powder. When the method disclosed by the invention is used, the production efficiency can be improved greatly, the production period is shortened, the product yield is increased, the product quality is improved, and the dose of palmitic acid is reduced (only 5 percent more is required).

Description

technical field [0001] The present invention relates to the synthetic method of organic compound, specifically a kind of synthetic method of L-ascorbyl palmitate. Background technique [0002] With the development of the economy and the improvement of living standards, people have higher and higher requirements for the quality of oil and oily food. Using antioxidants to delay the oxidation of fats and oily foods is the most effective means of storing fats and oily foods. L-ascorbyl palmitate is a new, fat-soluble, non-toxic and harmless multifunctional nutritional antioxidant received widespread attention. L-ascorbyl palmitate is also a new type of food additive recognized internationally in recent years, so it is widely used in grain, oil, food, medicine, health care products, cosmetics and other fields. [0003] L-ascorbyl palmitate is L-ascorbyl-6-palmitate, abbreviation: L-AP or AP; English name: L-ascorbyl palmitate; molecular formula: C 22 h 38 o 7 , Molecular wei...

AI Technical Summary

Problems solved by technology

But this method still has many deficiencies, such as low production efficiency (the total reaction time is as long as 22 hours, and the total product yield is only 80%); in the reaction process, an excess of 50% raw material palmitic acid is required, which increases the purification process. The difficulty of the steps also greatly increases the production cost; the wet balls precipitated from the reaction solution are easily emulsified when extracted with ethyl acetate and washed with water, which brings great difficulties to the subsequent acid washing process , and the organic phase will damage the material during the vacuum distillation process, affecting product quality