Color contact lens with colloidal crystal hydrogel as pigment and preparation method thereof

A technology for colloidal crystals and contact lenses, applied in the field of colored contact lenses and their preparation, can solve the problems of foreign body sensation, uneven surface, low biocompatibility of contact lenses, etc., and achieve brilliant colors and biocompatibility. Good, good usability effect

Inactive Publication Date: 2011-12-21
SOUTHEAST UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to provide a kind of colored contact lens with colloidal crystal hydrogel as pigment, which solves the problem of low biocompatibility and uneven surface of contact lens caused by the injection of colored pigment in the prior art, which makes the patient wear it Severe foreign body sensation and other problems

Method used

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  • Color contact lens with colloidal crystal hydrogel as pigment and preparation method thereof
  • Color contact lens with colloidal crystal hydrogel as pigment and preparation method thereof
  • Color contact lens with colloidal crystal hydrogel as pigment and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1 is the color contact lens that takes colloidal crystal hydrogel as pigment

[0030]

[0031]

[0032] 1. Preparation of colloidal crystal hydrogel pigment solution:

[0033] Monodisperse silica spherical nanoparticles with a diameter of 100 nanometers are uniformly dispersed in a mixed solution of acrylamide and methylenebisacrylamide, polymerized to obtain a colloidal crystal film, and the film is cut into tiny granular pigment units, which are micro-corroded. Nanoparticles in the unit, and after drying, the product is dispersed into a hydrogel solution (hydroxyethyl methacrylate (HEMA) and ethylene glycol dimethacrylate (EGDMA) The mixed solution (molar ratio 20:1), initiator azoisodibutylcyanide mass volume ratio 0.1%).

[0034] 2. Curing treatment of the hydrogel solution in the mold:

[0035] Add 100 microliters of the above-mentioned hydrogel solution into the mold used for contact lens preparation, and irradiate with a high-pressure mercury l...

Embodiment 2

[0038] Embodiment 2 is the colored contact lens that takes colloidal crystal hydrogel as pigment

[0039]

[0040] 1. Preparation of colloidal crystal hydrogel pigment solution:

[0041] Monodisperse silica spherical nanoparticles with a diameter of 100 nanometers are uniformly dispersed in a mixed solution of acrylamide and methylenebisacrylamide, polymerized to obtain a colloidal crystal film, and the film is cut into tiny granular pigment units, which are micro-corroded. Nanoparticles in the unit, and after drying, the product is dispersed into a hydrogel solution (siloxane methacrylate (SMA) and ethylene glycol dimethacrylate (EGDMA) for contact lens preparation ) mixed solution (mass ratio 20:1), initiator azoisodibutylcyanide mass volume ratio 0.1%).

[0042] 2. Curing treatment of the hydrogel solution in the mold:

[0043] Add 100 microliters of the above-mentioned hydrogel solution into the mold used for contact lens preparation, and irradiate with a high-pressur...

Embodiment 3

[0046] Embodiment 3 is the performance test of the colored contact lens that takes colloidal crystal hydrogel as pigment

[0047] (1) Light transmission test:

[0048] The color contact lens with colloidal crystal hydrogel as pigment was selected as the test object, and the light transmittance test was carried out on it, and the result showed that the transmittance of white light reached more than 94%;

[0049] (2) Water content test:

[0050] The water content test of colored contact lenses with colloidal crystal hydrogel as pigment by drying method shows that the water content is higher than 60%;

[0051] (3) Cytotoxicity test:

[0052] Since the cytotoxicity test can prepare an objective reaction to the potential toxicity of the test sample, the commonly used ISO9363-1 test method is used to investigate the cytotoxicity of the contact lens and accurately reflect its safety. In this method, the cytotoxicity reaction is divided into 0- Level 4 rating, the lower the level, th...

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Abstract

The invention discloses a color contact lens with colloid crystal aquogel serving as a pigment. The color contact lens disclosed by the invention is characterized by comprising a contact lens body (12), wherein the colloid crystal aquogel (11) serving as a pigment component of color elements is mixed in the contact lens body (12); and the colloid crystal aquogel and the aquogel of the contact lens body (12) form interpenetrating grids. The contact lens disclosed by the invention is bright in color, is elegant in appearance and has the advantages of good biocompatibility and good practicality.

Description

technical field [0001] The invention belongs to the technical field of contact lens material research, in particular to a colored contact lens using colloidal crystal hydrogel as a pigment and a preparation method thereof. Background technique [0002] In the past 30 years, the total number of people wearing contact lenses in the world has increased by 35 times, and colored contact lenses have gradually become popular due to the drive of the global fashion industry. According to incomplete statistics, my country's colored contact lenses currently account for more than 35% of the contact lens market. [0003] Colored contact lenses can be divided into two categories: the first category is a contact lens with transparent or opaque colored patterns only in the iris area of ​​the contact lens, which can reveal special colors and patterns in the iris area of ​​the contact lens; the second category Colored contact lenses use transparent colors to enhance the color of contact lens...

Claims

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Application Information

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IPC IPC(8): G02C7/04
Inventor 顾忠泽赵远锦谢卓颖金露李婷婷
Owner SOUTHEAST UNIV
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