Medical ultrasonic couplant capable of disinfection and sterilization and preparation technology thereof

Abstract

The invention relates to a medical ultrasonic couplant capable of disinfection and sterilization and a preparation technology thereof. The couplant comprises ingredients of, by weight, 0.2-0.6% of carbomer, 0.0-5% of sodium polyacrylate, 2-20% of glycerol, 0.2-6% of polyethylene glycol, 0.3-5% of bactericide, 0.1-5% of trichloroethanolamine and the balance of deionized water. The technology mainly comprises the following steps: weighing components according to a formula and completely dissolving a bactericide in a polyethylene glycol solution; then adding the polyethylene glycol solution of the bactericide into glycerol, and stirring uniformly; then respectively dispersing carbomer and sodium polyacrylate in a mixture of the bactericide, the polyethylene glycol and the glycerol to obtain an alcohol phase mixture of carbomer and sodium polyacrylate; at last, slowly adding the alcohol phase mixture into the deionized water with stirring, then adding a proper amount of trichloroethanolamine to adjust a pH to 5.5-8.0 to obtain a white or colorless transparent gel, and loading to obtain the medical ultrasonic couplant capable of disinfection and sterilization. The product has the functions of an ultrasonic couplant and the effect of disinfection and sterilization at the same time.

Description

technical field [0001] The invention relates to a medical ultrasonic coupling agent, in particular to a medical ultrasonic coupling agent which has the function of disinfecting and sterilizing an ultrasonic probe and an examination site of a patient and a preparation process thereof. Background technique [0002] The advent of medical ultrasonography is a major breakthrough in the medical field. However, since the propagation of sound waves in different media will cause attenuation, especially in the air, in order to obtain a satisfactory ultrasonic image, there needs to be a coupling substance between the ultrasonic probe and the detected part. The function of the medical ultrasonic couplant is to strengthen the ultrasonic probe. and the coupling between the human body surface. The 2008 version of the "Medical Ultrasonic Coupling Agent Industry Standard" stipulates that medical ultrasonic coupling agent is a water-soluble gel, which is defined as: in ultrasonic diagnosis a...

AI Technical Summary

Problems solved by technology

Patent CN100542615C dissolves 2,4,4-trichloro-2-hydroxydiphenyl ether in glycerol, and found 2,4,4-trichloro-2-hydroxydiphenyl ether from Modern Disinfection Science edited by Xue Guangbo The total solubility of glycerol is 0.15 (Xue Guangbo, Modern Disinfection (first sampan), People's Military Medical Press. 2002, p434), the content of glycerol is 4-7% calculation in this patent, so 2,4 , the highest content of 4-trichloro-2-hydroxydiphenyl ether in this patent is 1.05%, it is impossible to reach the maximum content of 2%, the higher part will be precipitated, it is not easy to completely dissolve, and there are defects

The coupling agent disclosed in the patent CN1108956A can play a role in sterilization and disinfection, avoid cross-infection, and damage the probe and body objects, but the preparation process is complicated, and it needs to be added with water to stir and stand still, which is inconvenient to use