Compound florfenicol injection and preparation method and application thereof
A technology of compound florfenicol and florfenicol, which is applied in the direction of medical formulas, medical preparations containing active ingredients, respiratory diseases, etc., can solve the problems of poor bioavailability and inconvenient use, and achieve convenient clinical use , Saving production costs, the effect of reasonable composition
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Embodiment 1
[0027] Take 250g of N-methyl-2-pyrrolidone, add 100g of florfenicol injection-grade raw material, stir to dissolve it, and set aside; take another 400g of propylene glycol, heat it to 60~80°C, add the prescribed amount of flunixin glucagon Mix 9 g of amine and 10 g of local analgesic benzyl alcohol, stir to dissolve, cool to about 40°C, mix with the stock solution, add polyethylene glycol 200 to the full amount, filter, pot, and sterilize at 100°C for 30 minutes to obtain.
Embodiment 2
[0029] Take 250g of N-methyl-2-pyrrolidone, add 100g of florfenicol injection-grade raw material, stir to dissolve, set aside; take another 400g of glycerin formal, heat to 60~80℃, add the prescribed amount of flunixin Mix 9g of meglumine and 10g of local analgesic benzyl alcohol, stir to dissolve, cool to about 40°C, mix with the reserve solution, add polyethylene glycol 200 to the full amount, filter, pot, sterilize at 100°C for 30 minutes, and obtain .
Embodiment 3
[0031] Take 250g of N-methyl-2-pyrrolidone, add 250g of florfenicol injection-grade raw materials, stir to dissolve, and set aside; take another 400g of propylene glycol, heat to 60~80°C, add the prescribed amount of flunixin glucagon Mix 23 g of amine and 10 g of local analgesic benzyl alcohol, stir to dissolve, cool to about 40°C, mix with the reserve solution, add polyethylene glycol 300 to the full amount, filter, pot, and sterilize at 100°C for 30 minutes to obtain the product.
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