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Method for preparing capsules containing prepared rehmannia root, white paeony root, Chinese angelica and szechuan lovage rhizome and application

A technology of capsules and soup recipes, which is applied in the preparation and application of Siwu Capsules, can solve the problems of low extraction rate and achieve the effects of safe production environment, good application effect and increased yield

Active Publication Date: 2011-09-14
YOUCARE PHARMA GROUP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The conventional extraction methods used in the preparation of traditional Chinese medicine mainly include decoction, reflux, dipping, percolation, etc. They are easy to use, but have the disadvantage of low extraction rate.

Method used

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  • Method for preparing capsules containing prepared rehmannia root, white paeony root, Chinese angelica and szechuan lovage rhizome and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] 1. Put 1 kg of raw materials of Angelica sinensis and 1 kg of raw materials of Chuanxiong Rhizoma Rhizoma Chuanxiong into a traditional Chinese medicine grinder to crush to an average particle size of 200 mesh, and filter through a 180-mesh sieve to obtain Angelica and Ligusticum Chuanxiong with an average particle size of 200 mesh;

[0027] 2. Put the obtained angelica and chuanxiong into the extraction tank, add 14L of water, put 700g of immobilized cellulase and immobilized hemicellulase purchased from Zhuhai Baikang Biotechnology Co., Ltd. into the extraction tank, immobilized cellulose Enzyme pellets and immobilized hemicellulase pellets have an enzyme activity of 100IU / g, a particle size of 700μm, and are hydrolyzed for 2 hours at 55°C;

[0028] 3. After enzymolysis, filter the enzymolysis solution through a 60-mesh sieve to obtain immobilized cellulase pellets and immobilized hemicellulase pellets, collect the filtrate, immobilize cellulase, and immobilize hemicel...

Embodiment 2

[0038] 1. Put 2 kg of raw materials of Angelica sinensis and 1 kg of raw materials of Rhizoma Chuanxiong into a traditional Chinese medicine pulverizer to pulverize to an average particle size of 200 mesh, and filter through a sieve of 180 mesh to obtain Angelica and Rhizoma Chuanxiong with an average particle size of 200 mesh;

[0039] 2. Put the obtained angelica and chuanxiong into the extraction tank, add 21 L of water, put 1.5 kg of immobilized cellulase and immobilized hemicellulase purchased from Zhuhai Baikang Biotechnology Co., Ltd. into the extraction tank, and immobilize the fiber The enzymatic activity of both the enzymatic bead and the immobilized hemicellulase bead is 100IU / g, the particle size is 700μm, and the enzymolysis is carried out at 55°C for 2 hours;

[0040] 3. After enzymolysis, filter the enzymolysis solution through a 60-mesh sieve to obtain immobilized cellulase pellets and immobilized hemicellulase pellets, collect the filtrate, immobilize cellulase...

Embodiment 3

[0050] 1. Put 1kg of angelica raw material and 1kg of Chuanxiong raw material into the extraction tank, add 18L of water, distill for 3 hours, extract 20g of volatile oil of angelica and Chuanxiong, and the rest is medicine residue and water;

[0051] 2. Combine the above remaining medicinal residues and water with 1 kg of Radix Paeoniae Alba and 1 kg of Rehmannia glutinosa, add water to extract: add 10 L of water for the first time and decoct for 2 hours, add 6 L of water for the second time and decoct for 2 hours, heat until boiling and start timing. The two extracts were combined and concentrated to a relative density of 1.25;

[0052] 3. Dry under the condition of 80°C. When the water content of the extract is dried to 2.5%, stop drying to obtain 0.48kg of extract of Siwutangfang extract;

[0053] 4. The obtained extract is crushed to an average particle size of 30 mesh, and passed through a 40 mesh sieve to obtain Siwu Decoction extract particles with a uniform size and a...

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Abstract

The invention relates to a method for preparing a Chinese medicinal composition and application, in particular to a method for preparing capsules containing prepared rehmannia root, white paeony root, Chinese angelica and szechuan lovage rhizome and application, and aims to provide a method for preparing a high-yield capsules containing prepared rehmannia root, white paeony root, Chinese angelica and szechuan lovage rhizome and application of the capsules in the preparation of medicaments for treating alopecia and leukotrichia. The method for preparing the capsules containing prepared rehmannia root, white paeony root, Chinese angelica and szechuan lovage rhizome comprises the following steps of: preparing content granules, and filling into capsules, wherein a method for preparing the content granules comprises the following steps of: crushing, performing enzymolysis, filtering, washing, distilling to extract volatile oil, adding water to extract extract of decoction containing prepared rehmannia root, white paeony root, Chinese angelica and szechuan lovage rhizome, drying to prepare extract granules of the decoction containing prepared rehmannia root, white paeony root, Chinese angelica and szechuan lovage rhizome, mixing the volatile oil and the extract granules of the decoction containing prepared rehmannia root, white paeony root, Chinese angelica and szechuan lovage rhizome, and preparing the content granules. The invention also relates to the application of the capsules containing prepared rehmannia root, white paeony root, Chinese angelica and szechuan lovage rhizome in the preparation of the medicaments for treating alopecia and leukotrichia.

Description

technical field [0001] The present invention relates to a preparation method and application of a plant-derived composition, in particular to a preparation method of a composition derived from four traditional Chinese medicines of Rehmannia glutinosa, Radix Paeoniae Alba, Angelica Sinensis, and Chuanxiong Rhizoma and its use in the preparation of medicines for treating alopecia and white hair Applications. Background technique [0002] Siwu Decoction comes from the "Taiping Huimin Heji Bureau Prescription" in the Song Dynasty, and is composed of four traditional Chinese medicines: rehmannia glutinosa, white peony root, angelica, and chuanxiong. It has the functions of nourishing blood, promoting blood circulation, and regulating menstruation. Siwu Decoction is used for dysmenorrhea, irregular menstruation, miscarriage, infertility, abnormal fetal position, pelvic inflammatory disease, angioneurotic headache, hypocalcemic convulsions, nephritis and other diseases. The treatm...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61K9/48A61P17/00A61P17/14
Inventor 徐为公
Owner YOUCARE PHARMA GROUP
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